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Corynoxine B derivative CB6 prevents Parkinsonian toxicity in mice by inducing PIK3C3 complex-dependent autophagy
Journal article
Zhu, Zhou, Liu, Liang feng, Su, Cheng fu, Liu, Jia, Tong, Benjamin Chun Kit, Iyaswamy, Ashok, Krishnamoorthi, Senthilkumar, Sreenivasmurthy, Sravan Gopalkrishnashetty, Guan, Xin jie, Kan, Yu xuan, Xie, Wen jian, Zhao, Chen liang, Cheung, King ho, Lu, Jia hong, Tan, Jie qiong, Zhang, Hong jie, Song, Ju xian, Li, Min. Corynoxine B derivative CB6 prevents Parkinsonian toxicity in mice by inducing PIK3C3 complex-dependent autophagy[J]. Acta Pharmacologica Sinica, 2022, 43(10), 2511-2526.
Authors:
Zhu, Zhou
;
Liu, Liang feng
;
Su, Cheng fu
;
Liu, Jia
;
Tong, Benjamin Chun Kit
; et al.
Favorite
|
TC[WOS]:
25
TC[Scopus]:
21
IF:
6.9
/
7.6
|
Submit date:2022/05/17
Autophagy
Corynoxine b
Dopaminergic Neuron
Cascaded Parsing of Human-Object Interaction Recognition
Journal article
Zhou, Tianfei, Qi, Siyuan, Wang, Wenguan, Shen, Jianbing, Zhu, Song Chun. Cascaded Parsing of Human-Object Interaction Recognition[J]. IEEE Transactions on Pattern Analysis and Machine Intelligence, 2022, 44(6), 2827-2840.
Authors:
Zhou, Tianfei
;
Qi, Siyuan
;
Wang, Wenguan
;
Shen, Jianbing
;
Zhu, Song Chun
Favorite
|
TC[WOS]:
100
TC[Scopus]:
85
IF:
20.8
/
22.2
|
Submit date:2022/05/31
Cascaded Parsing
Fine-grained Relation Segmentation
Human-object Interaction Recognition
TFEB, a master regulator of autophagy and biogenesis, unexpectedly promotes apoptosis in response to the cyclopentenone prostaglandin 15d-PGJ2
Journal article
Yang, Chuan bin, Liu, Jia, Tong, Benjamin Chun Kit, Wang, Zi ying, Zhu, Zhou, Su, Cheng fu, Sreenivasmurthy, Sravan Gopalkrishnashetty, Wu, Jia xi, Iyaswamy, Ashok, Krishnamoorthi, Senthilkumar, Huang, Shi ying, Cheung, King ho, Song, Ju xian, Tan, Jie qiong, Lu, Jia hong, Li, Min. TFEB, a master regulator of autophagy and biogenesis, unexpectedly promotes apoptosis in response to the cyclopentenone prostaglandin 15d-PGJ2[J]. Acta Pharmacologica Sinica, 2022, 43(5), 1251-1263.
Authors:
Yang, Chuan bin
;
Liu, Jia
;
Tong, Benjamin Chun Kit
;
Wang, Zi ying
;
Zhu, Zhou
; et al.
Favorite
|
TC[WOS]:
18
TC[Scopus]:
19
IF:
6.9
/
7.6
|
Submit date:2022/05/13
15-deoxy-∆-12,14-prostaglandin J2 (15d-pgJ2)
Apoptosis
Atf4
Autophagy And Lysosome Biogenesis
Er Stress
Transcriptional Factor Eb (tfEb)
Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models
Journal article
Iyaswamy, Ashok, Wang, Xueli, Krishnamoorthi, Senthilkumar, Kaliamoorthy, Venkatapathy, Sreenivasmurthy, Sravan G., Kumar Durairajan, Siva Sundara, Song, Ju Xian, Tong, Benjamin Chun kit, Zhu, Zhou, Su, Cheng Fu, Liu, Jia, Cheung, King Ho, Lu, Jia Hong, Tan, Jie Qiong, Li, Hung Wing, Wong, Man Shing, Li, Min. Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models[J]. Redox Biology, 2022, 51, 102280.
Authors:
Iyaswamy, Ashok
;
Wang, Xueli
;
Krishnamoorthi, Senthilkumar
;
Kaliamoorthy, Venkatapathy
;
Sreenivasmurthy, Sravan G.
; et al.
Favorite
|
TC[WOS]:
47
TC[Scopus]:
51
IF:
10.7
/
11.7
|
Submit date:2022/05/13
Theranostic
Alzheimer’s Disease
Aβ-targeting
Aβ-aggregate Inhibition
3xtg-ad
5xfad
Molecular mechanism of Spatholobi Caulis in treatment of ovarian cancer based on network pharmacology and experimental verification 基于网络药理学和实验验证分析鸡血藤治疗卵巢癌的分子机制
Journal article
Zhu, Shi Chun, Cai, Jun, Wu, Cheng Yu, Cheng, Chun Song. Molecular mechanism of Spatholobi Caulis in treatment of ovarian cancer based on network pharmacology and experimental verification 基于网络药理学和实验验证分析鸡血藤治疗卵巢癌的分子机制[J]. Zhongguo Zhongyao Zazhi, 2022, 47(3), 786-795.
Authors:
Zhu, Shi Chun
;
Cai, Jun
;
Wu, Cheng Yu
;
Cheng, Chun Song
Favorite
|
TC[Scopus]:
3
|
Submit date:2023/01/30
Molecular docking
Network pharmacology
Ovarian cancer
Prunetin
Spatholobi Caulis
Lysosomal TPCN (two pore segment channel) inhibition ameliorates beta-amyloid pathology and mitigates memory impairment in Alzheimer disease
Journal article
Tong, Benjamin Chun Kit, Wu, Aston Jiaxi, Huang, Alexis Shiying, Dong, Rui, Malampati, Sandeep, Iyaswamy, Ashok, Krishnamoorthi, Senthilkumar, Sreenivasmurthy, Sravan Gopalkrishnashetty, Zhu, Zhou, Su, Chengfu, Liu, Jia, Song, Juxian, Lu, Jia Hong, Tan, Jieqiong, Pan, Weidong, Li, Min, Cheung, King Ho. Lysosomal TPCN (two pore segment channel) inhibition ameliorates beta-amyloid pathology and mitigates memory impairment in Alzheimer disease[J]. Autophagy, 2021, 18(3), 624-642.
Authors:
Tong, Benjamin Chun Kit
;
Wu, Aston Jiaxi
;
Huang, Alexis Shiying
;
Dong, Rui
;
Malampati, Sandeep
; et al.
Favorite
|
TC[WOS]:
30
TC[Scopus]:
30
IF:
14.6
/
16.8
|
Submit date:2022/05/17
Alzheimer Disease
Autophagy-lysosomal Pathway
Calcium Ion
Presenilin-1
Two Pore Segment Channel 2
A curcumin derivative activates TFEB and protects against parkinsonian neurotoxicity in vitro
Journal article
Wang,Ziying, Yang,Chuanbin, Liu,Jia, Tong,Benjamin Chun Kit, Zhu,Zhou, Malampati,Sandeep, Sreenivasmurthy,Sravan Gopalkrishnashetty, Cheung,King Ho, Iyaswamy,Ashok, Su,Chengfu, Lu,Jiahong, Song,Juxian, Li,Min. A curcumin derivative activates TFEB and protects against parkinsonian neurotoxicity in vitro[J]. International Journal of Molecular Sciences, 2020, 21(4), 1515.
Authors:
Wang,Ziying
;
Yang,Chuanbin
;
Liu,Jia
;
Tong,Benjamin Chun Kit
;
Zhu,Zhou
; et al.
Favorite
|
TC[WOS]:
33
TC[Scopus]:
40
IF:
4.9
/
5.6
|
Submit date:2021/03/02
Curcumin Derivatives
Mtorc1
Parkinson’s Disease
Tfeb
Α-synuclein
A small molecule transcription factor EB activator ameliorates beta-amyloid precursor protein and Tau pathology in Alzheimer's disease models
Journal article
Ju-Xian Song, Sandeep Malampati, Yu Zeng, Siva Sundara Kumar Durairajan, Chuan-Bin Yang, Benjamin Chun-Kit Tong, Ashok Iyaswamy, Wen-Bin Shang, Sreenivasmurthy,Sravan Gopalkrishnashetty, Zhou Zhu, King-Ho Cheung, Jia-Hong Lu, Chunzhi Tang, Nenggui Xu, Min Li. A small molecule transcription factor EB activator ameliorates beta-amyloid precursor protein and Tau pathology in Alzheimer's disease models[J]. AGING CELL, 2020, 19(2).
Authors:
Ju-Xian Song
;
Sandeep Malampati
;
Yu Zeng
;
Siva Sundara Kumar Durairajan
;
Chuan-Bin Yang
; et al.
Favorite
|
TC[WOS]:
104
TC[Scopus]:
113
IF:
8.0
/
9.7
|
Submit date:2021/03/02
Alzheimer's Disease
Beta-amyloid
Curcumin Analog C1
Mapt/tau
Tfeb
Targeting Aggrephagy for the Treatment of Alzheimer's Disease
Journal article
Malampati, Sandeep, Song, Ju Xian, Chun-Kit Tong, Benjamin, Nalluri, Anusha, Yang, Chuan Bin, Wang, Ziying, Gopalkrishnashetty Sreenivasmurthy, Sravan, Zhu, Zhou, Liu, Jia, Su, Chengfu, Krishnamoorthi, Senthilkumar, Iyaswamy, Ashok, Cheung, King Ho, Lu, Jia Hong, Li, Min. Targeting Aggrephagy for the Treatment of Alzheimer's Disease[J]. Cells, 2020, 9(2), 311.
Authors:
Malampati, Sandeep
;
Song, Ju Xian
;
Chun-Kit Tong, Benjamin
;
Nalluri, Anusha
;
Yang, Chuan Bin
; et al.
Favorite
|
TC[WOS]:
36
TC[Scopus]:
38
IF:
5.1
/
6.0
|
Submit date:2021/12/03
Aggregates
Aggrephagy
Alzheimer’s Disease
Selective Autophagy
Balancing mTOR signaling and autophagy in the treatment of Parkinson’s disease
Journal article
Zhu,Zhou, Yang,Chuanbin, Iyaswamy,Ashok, Krishnamoorthi,Senthilkumar, Sreenivasmurthy,Sravan Gopalkrishnashetty, Liu,Jia, Wang,Ziying, Tong,Benjamin Chun Kit, Song,Juxian, Lu,Jiahong, Cheung,King Ho, Li,Min. Balancing mTOR signaling and autophagy in the treatment of Parkinson’s disease[J]. International Journal of Molecular Sciences, 2019, 20(3), 728.
Authors:
Zhu,Zhou
;
Yang,Chuanbin
;
Iyaswamy,Ashok
;
Krishnamoorthi,Senthilkumar
;
Sreenivasmurthy,Sravan Gopalkrishnashetty
; et al.
Favorite
|
TC[WOS]:
165
TC[Scopus]:
172
|
Submit date:2021/03/02
Autophagy
Mtor
Parkinson’s Disease