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Discovery of potent LRRK2 inhibitors by ensemble virtual screening strategy and bioactivity evaluation Journal article
Gong, Xiaoqing, Li, Shuli, Huang, Junli, Tan, Shuoyan, Zhang, Qianqian, Tian, Yanan, Li, Qin, Wang, Lingling, Tong, Henry H.Y., Yao, Xiaojun, Chen, Chunxia, Lee, Simon Ming Yuen, Liu, Huanxiang. Discovery of potent LRRK2 inhibitors by ensemble virtual screening strategy and bioactivity evaluation[J]. European Journal of Medicinal Chemistry, 2024, 279, 116812.
Authors:  Gong, Xiaoqing;  Li, Shuli;  Huang, Junli;  Tan, Shuoyan;  Zhang, Qianqian; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:6.0/6.1 | Submit date：2024/10/10
Fingerprint  Lrrk2  Molecular Docking  Pharmacophore  Virtual Screening  Zebrafish  
Isoalantolactone/hydroxamic acid hybrids as potent dual STAT3/HDAC inhibitors and self-assembled nanoparticles for cancer therapy Journal article
Mo, Hualong, Liu, Jie Ying, Su, Zhengxi, Zhao, Deng Gao, Ma, Yan Yan, Zhang, Kun, Wang, Qi, Fu, Chun, Wang, Yao, Chen, Meiwan, Hu, Burong. Isoalantolactone/hydroxamic acid hybrids as potent dual STAT3/HDAC inhibitors and self-assembled nanoparticles for cancer therapy[J]. European Journal of Medicinal Chemistry, 2024, 277, 116765.
Authors:  Mo, Hualong;  Liu, Jie Ying;  Su, Zhengxi;  Zhao, Deng Gao;  Ma, Yan Yan; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:6.0/6.1 | Submit date：2024/09/03
Antitumor  Hdac  Isoalantolactone  Self-assembled Nanoparticles  Stat3  
Protective effects of Amauroderma rugosum on dextran sulfate sodium-induced ulcerative colitis through the regulation of macrophage polarization and suppression of oxidative stress Journal article
Li, Jingjing, Luo, Xi, Shiu, Polly Ho Ting, Cheng, Yanfen, Nie, Xin, Rangsinth, Panthakarn, Lau, Benson Wui Man, Zheng, Chengwen, Li, Xuebo, Li, Renkai, Lee, Simon Ming Yuen, Fu, Chaomei, Seto, Sai Wang, Zhang, Jinming, Leung, George Pak Heng. Protective effects of Amauroderma rugosum on dextran sulfate sodium-induced ulcerative colitis through the regulation of macrophage polarization and suppression of oxidative stress[J]. Biomedicine and Pharmacotherapy, 2024, 176, 116901.
Authors:  Li, Jingjing;  Luo, Xi;  Shiu, Polly Ho Ting;  Cheng, Yanfen;  Nie, Xin; et al.
Favorite | TC[WOS]:0 TC[Scopus]:1  IF:6.9/6.8 | Submit date：2024/07/04
Amauroderma Rugosum  Macrophage Polarization  Oxidative Stress  Ulcerative Colitis  
Rupatadine inhibits colorectal cancer cell proliferation through the PIP5K1A/Akt/CDK2 pathway Journal article
Jiang, Lei, Zhang, Zhibo, Luo, Zhaofeng, Li, Luan, Yuan, Shengtao, Cui, Min, He, Ke, Xiao, Jing. Rupatadine inhibits colorectal cancer cell proliferation through the PIP5K1A/Akt/CDK2 pathway[J]. Biomedicine and Pharmacotherapy, 2024, 176, 116826.
Authors:  Jiang, Lei;  Zhang, Zhibo;  Luo, Zhaofeng;  Li, Luan;  Yuan, Shengtao; et al.
Favorite | TC[WOS]:0 TC[Scopus]:1  IF:6.9/6.8 | Submit date：2024/07/04
Cell Cycle  Cell Proliferation  Colorectal Cancer  Pip5k1a  Rupatadine  
Upregulation of Nrf2 signaling: A key molecular mechanism of Baicalin's neuroprotective action against diabetes-induced cognitive impairment Journal article
Zheng, Yanfang, Wang, Chenxiang, Liu, Wenjing, Chen, Jiaying, Sun, Yibin, Chang, Dennis, Wang, Huan, Xu, Wen, Lu, Jin Jian, Zhou, Xian, Huang, Mingqing. Upregulation of Nrf2 signaling: A key molecular mechanism of Baicalin's neuroprotective action against diabetes-induced cognitive impairment[J]. Biomedicine and Pharmacotherapy, 2024, 174, 116579.
Authors:  Zheng, Yanfang;  Wang, Chenxiang;  Liu, Wenjing;  Chen, Jiaying;  Sun, Yibin; et al.
Favorite | TC[WOS]:3 TC[Scopus]:4  IF:6.9/6.8 | Submit date：2024/05/16
Baicalin  Diabetes-associated Cognitive Deficits  Keap1-nrf2  Neuroinflammation  Nlrp3 Inflammasome  Oxidative Stress  
Unveil the mechanism for EHMT – A novel triterpenoid inhibits proliferation and induces apoptosis in colon cancer through ROS-mediated JNK signaling pathway Journal article
Wu, Qiushuang, Song, Min, Luo, Siyuan, Guo, Libin, Zhang, Qingwen, Kwok, Hang Fai. Unveil the mechanism for EHMT – A novel triterpenoid inhibits proliferation and induces apoptosis in colon cancer through ROS-mediated JNK signaling pathway[J]. Biomedicine and Pharmacotherapy, 2024, 174, 116469.
Authors:  Wu, Qiushuang;  Song, Min;  Luo, Siyuan;  Guo, Libin;  Zhang, Qingwen; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:6.9/6.8 | Submit date：2024/05/16
Apoptosis  Colon Cancer  Jnk Pathways  Natural Products  Ros  Triterpenoid  
Oxyimperatorin attenuates LPS-induced microglial activation in vitro and in vivo via suppressing NF-κB p65 signaling Journal article
Lu, Changcheng, Huang, Chen, Qu, Shuhui, Lin, Huiyuan, Zhong, Hai Jing, Chong, Cheong Meng. Oxyimperatorin attenuates LPS-induced microglial activation in vitro and in vivo via suppressing NF-κB p65 signaling[J]. Biomedicine and Pharmacotherapy, 2024, 173, 116379.
Authors:  Lu, Changcheng;  Huang, Chen;  Qu, Shuhui;  Lin, Huiyuan;  Zhong, Hai Jing; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:6.9/6.8 | Submit date：2024/05/02
Microglia  Neuroinflammation  Nf-κb P65  Oxyimperatorin  Pro-inflammatory Cytokines  
Anti-breast cancer-induced cardiomyopathy: Mechanisms and future directions Review article
2023
Authors:  Chunping Liu;  Huiqi Chen;  Sien Guo;  Qiaojing Liu;  Zhijun Chen; et al.
Favorite | TC[WOS]:7 TC[Scopus]:9  IF:6.9/6.8 | Submit date：2023/09/22
Anthracycline  Breast Cancer  Cardiomyopathy  Cardiotoxicity  Chemotherapy  Trastuzumab  
A cell-impermeable luminogenic probe for near-infrared imaging of prostate-specific membrane antigen in prostate cancer microenvironments Journal article
Yang,Xifang, Nao,Sang Cuo, Lin,Chuankai, Kong,Lingtan, Wang,Jing, Ko,Chung Nga, Liu,Jinbiao, Ma,Dik Lung, Leung,Chung Hang, Wang,Wanhe. A cell-impermeable luminogenic probe for near-infrared imaging of prostate-specific membrane antigen in prostate cancer microenvironments[J]. European Journal of Medicinal Chemistry, 2023, 259, 115659.
Authors:  Yang,Xifang;  Nao,Sang Cuo;  Lin,Chuankai;  Kong,Lingtan;  Wang,Jing; et al.
Favorite | TC[WOS]:6 TC[Scopus]:6  IF:6.0/6.1 | Submit date：2023/08/03
Nir  Luminogenic Probe  Cell Impermeability  Wash-free  Iridium(Iii) Complex  Prostate Cancer  Prostate-specific Membrane Antigen  
The role of Sirtuin 1 and its activators in age-related lung disease Journal article
Chaoqun Sun, Shuyou Bai, Yanmei Liang, Dewei Liu, Jinyu Liao, Yujuan Chen, Xuanna Zhao, Bin Wu, Dan Huang, Min Chen, Dong Wu. The role of Sirtuin 1 and its activators in age-related lung disease[J]. Biomedicine and Pharmacotherapy, 2023, 162, 114573.
Authors:  Chaoqun Sun;  Shuyou Bai;  Yanmei Liang;  Dewei Liu;  Jinyu Liao; et al.
Favorite | TC[WOS]:13 TC[Scopus]:10  IF:6.9/6.8 | Submit date：2023/09/28
Age-related Lung Disease  Anti-aging  Chinese Herbal Medicine  Lung Aging  Sirt1