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Oxyphylla A exerts antiparkinsonian effects by ameliorating 6-OHDA-induced mitochondrial dysfunction and dyskinesia in vitro and in vivo Journal article
Shao, Min, Zhao, Chen, Pan, Zhijian, Yang, Xuanjun, Gao, Cheng, Kam, Gloria Hio Cheng, Zhou, Hefeng, Lee, Simon Ming Yuen. Oxyphylla A exerts antiparkinsonian effects by ameliorating 6-OHDA-induced mitochondrial dysfunction and dyskinesia in vitro and in vivo[J]. Chemico-Biological Interactions, 2024, 403, 111224.
Authors:  Shao, Min;  Zhao, Chen;  Pan, Zhijian;  Yang, Xuanjun;  Gao, Cheng; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:4.7/4.6 | Submit date：2024/10/10
6-ohda  Mitochondria  Neuroprotection  Oxyphylla a  Parkinson's Disease  Target Prediction  
J24335 exerts neuroprotective effects against 6-hydroxydopamine-induced lesions in PC12 cells and mice Journal article
Pan, Zhijian, Shao, Min, Zhao, Chen, Yang, Xuanjun, Li, Haitao, Cui, Guozhen, Liang, Xiaonan, Yu, Chao Wu, Ye, Qingqing, Gao, Cheng, Di, Lijun, Chern, Ji Wang, Zhou, Hefeng, Lee, Simon Ming Yuen. J24335 exerts neuroprotective effects against 6-hydroxydopamine-induced lesions in PC12 cells and mice[J]. European Journal of Pharmaceutical Sciences, 2024, 194, 106696.
Authors:  Pan, Zhijian;  Shao, Min;  Zhao, Chen;  Yang, Xuanjun;  Li, Haitao; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:4.3/4.2 | Submit date：2024/04/02
6-ohda  J24335  Mitochondria Dysfunction  Neurotoxicity  Parkinson's Disease  Target Prediction  
Artemisinin Confers Neuroprotection against 6-OHDA-Induced Neuronal Injury In Vitro and In Vivo through Activation of the ERK1/2 Pathway Journal article
Qin Li, Shuai Li, Jiankang Fang, Chao Yang, Xia Zhao, Qing Wang, Wenshu Zhou, Zheng WH(鄭文華). Artemisinin Confers Neuroprotection against 6-OHDA-Induced Neuronal Injury In Vitro and In Vivo through Activation of the ERK1/2 Pathway[J]. Molecules, 2023, 28(14).
Authors:  Qin Li;  Shuai Li;  Jiankang Fang;  Chao Yang;  Xia Zhao; et al.
Favorite | TC[WOS]:5 TC[Scopus]:5  IF:4.2/4.6 | Submit date：2023/08/14
Artemisinin  6-ohda  Mptp/mpp++  Apoptosis  Parkinson’s Disease  
Pinocembrin-7-Methylether Protects SH-SY5Y Cells Against 6-Hydroxydopamine-Induced Neurotoxicity via Modulating Nrf2 Induction Through AKT and ERK Pathways Journal article
Zou, Zhi Cong, Fu, Ji Jun, Dang, Yuan Ye, Zhang, Qian, Wang, Xiu Fen, Chen, Han Bin, Jia, Xue Jing, Lee, Simon Ming Yuen, Li, Chu Wen. Pinocembrin-7-Methylether Protects SH-SY5Y Cells Against 6-Hydroxydopamine-Induced Neurotoxicity via Modulating Nrf2 Induction Through AKT and ERK Pathways[J]. Neurotoxicity Research, 2021, 39(4), 1323-1337.
Authors:  Zou, Zhi Cong;  Fu, Ji Jun;  Dang, Yuan Ye;  Zhang, Qian;  Wang, Xiu Fen; et al.
Favorite | TC[WOS]:14 TC[Scopus]:16  IF:2.9/3.4 | Submit date：2021/12/08
6-ohda  Nrf2 Induction  Oxidative Stress  Parkinson’s Disease  Pinocembrin-7-methylether  
Schisantherin A protects against 6-OHDA-induced dopaminergic neuron damage in zebrafish and cytotoxicity in SH-SY5Y cells through the ROS/NO and AKT/GSK3β pathways Journal article
Lun Qing Zhang, Fei Sa, Cheong Meng Chong, Ying Wang, Zhong Yan Zhou, Raymond Chuen Chung Chang, Shun Wan Chan, Pui Man Hoi, Simon Ming Yuen Lee. Schisantherin A protects against 6-OHDA-induced dopaminergic neuron damage in zebrafish and cytotoxicity in SH-SY5Y cells through the ROS/NO and AKT/GSK3β pathways[J]. Journal of Ethnopharmacology, 2015, 8-15.
Authors:  Lun Qing Zhang;  Fei Sa;  Cheong Meng Chong;  Ying Wang;  Zhong Yan Zhou; et al.
Favorite | TC[WOS]:51 TC[Scopus]:60 | Submit date：2022/07/27
6-hydroxydopamine (6-ohda)  Oxidative Stress  Parkinson׳s Disease  Schisantherin a  
Schisantherin A protects against 6-OHDA-induced dopaminergic neuron damage in zebrafish and cytotoxicity in SH-SY5Y cells through the ROS/NO and AKT/GSK3 β pathways Journal article
Lun Qing Zhang, Fei Sa, Cheong Meng Chong, Ying Wang, Zhong Yan Zhou, Raymond Chuen Chung Chang, Shun Wan Chan, Pui Man Hoi, Simon Ming Yuen Lee. Schisantherin A protects against 6-OHDA-induced dopaminergic neuron damage in zebrafish and cytotoxicity in SH-SY5Y cells through the ROS/NO and AKT/GSK3 β pathways[J]. JOURNAL OF ETHNOPHARMACOLOGY, 2015, 170, 8-15.
Authors:  Lun Qing Zhang;  Fei Sa;  Cheong Meng Chong;  Ying Wang;  Zhong Yan Zhou; et al.
Favorite | TC[WOS]:51 TC[Scopus]:60  IF:4.8/4.8 | Submit date：2020/04/15
6-hydroxydopamine (6-ohda)  Oxidative Stress  Parkinson׳s Disease  Schisantherin a  
Indirubin-3-Oxime Effectively Prevents 6OHDA-Induced Neurotoxicity in PC12 Cells via Activating MEF2D Through the Inhibition of GSK3β Journal article
Shengquan Hu, Wei Cui, Zaijun Zhang, Shinghung Mak, Daping Xu, Gang Li, Yuanjia Hu, Yuqiang Wang, Mingyuen Lee, Karl Wahkeung Tsim, Yifan Han. Indirubin-3-Oxime Effectively Prevents 6OHDA-Induced Neurotoxicity in PC12 Cells via Activating MEF2D Through the Inhibition of GSK3β[J]. Journal of Molecular Neuroscience, 2015, 57(4), 561–570.
Authors:  Shengquan Hu;  Wei Cui;  Zaijun Zhang;  Shinghung Mak;  Daping Xu; et al.
Favorite | TC[WOS]:27 TC[Scopus]:30  IF:2.8/2.8 | Submit date：2018/10/30
6ohda  Gsk3β  Indirubin-3-oxime  Mef2d  Neuroprotection  Parkinson’s Disease  
Therapeutic effects of multifunctional tetramethylpyrazine nitrone on models of Parkinson's disease in vitro and in vivo Journal article
Baojian Guo, Daping Xu, Hongwei Duan, Jing Du, Zaijun Zhang, Simon MingYuen Lee, Yuqiang Wang. Therapeutic effects of multifunctional tetramethylpyrazine nitrone on models of Parkinson's disease in vitro and in vivo[J]. Biological and Pharmaceutical Bulletin, 2014, 37(2), 274-285.
Authors:  Baojian Guo;  Daping Xu;  Hongwei Duan;  Jing Du;  Zaijun Zhang; et al.
Favorite | TC[WOS]:37 TC[Scopus]:43 | Submit date：2018/11/06
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (Mptp)  6-hydroxydopamine (6-ohda)  Oxidative Stress  Parkinson's Disease  Tetramethylpyrazine Nitrone  
Danshensu protects against 6-hydroxydopamine-induced damage of PC12 cells in vitro and dopaminergic neurons in zebrafish Journal article
Cheong-Meng Chong, Zhong-Yan Zhou, Valentina Razmovski-Naumovski, Guo-Zhen Cui, Lun-Qing Zhang, Fei Sa, Pui-Man Hoi, Kelvin Chan, Simon Ming-Yuen Lee. Danshensu protects against 6-hydroxydopamine-induced damage of PC12 cells in vitro and dopaminergic neurons in zebrafish[J]. Neuroscience Letters, 2013, 543, 121-125.
Authors:  Cheong-Meng Chong;  Zhong-Yan Zhou;  Valentina Razmovski-Naumovski;  Guo-Zhen Cui;  Lun-Qing Zhang; et al.
Favorite | TC[WOS]:70 TC[Scopus]:71  IF:2.5/2.5 | Submit date：2018/11/06
6-ohda  Neurodegeneration  Ros  Zebrafish