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Small molecule deoxynyboquinone triggers alkylation and ubiquitination of Keap1 at Cys489 on Kelch domain for Nrf2 activation and inflammatory therapy
Journal article
Linghu, Ke-Gang, Zhang, Tian, Zhang, Guang-Tao, Lv, Peng, Zhang, Wenjun, Zhao, Guanding, Xiong, Shihong, Zhao, Mingming, Chen, Meiwan, HU YUANJIA, Zhang, Changsheng, Yu, Hua. Small molecule deoxynyboquinone triggers alkylation and ubiquitination of Keap1 at Cys489 on Kelch domain for Nrf2 activation and inflammatory therapy[J]. Journal of Pharmaceutical Analysis, 2024, 14(3), 401-415.
Authors:
Linghu, Ke-Gang
;
Zhang, Tian
;
Zhang, Guang-Tao
;
Lv, Peng
;
Zhang, Wenjun
; et al.
Favorite
|
TC[WOS]:
6
TC[Scopus]:
9
IF:
6.1
/
6.8
|
Submit date:2024/01/02
Deoxynyboquinone
Anti-inflammation
Target
Keap1/nrf2
Alkylation
Ubiquitination
Highly Site- and Enantioselective N—H Functionalization of N-Monosubstituted Aniline Derivatives Affording Pyrazolones Bearing a Quaternary Stereocenter
Journal article
Wang, Guan Jun, Zhang, Shu Yu, Sun, Zhen Liang, Li, Peng, Ding, Tong Mei. Highly Site- and Enantioselective N—H Functionalization of N-Monosubstituted Aniline Derivatives Affording Pyrazolones Bearing a Quaternary Stereocenter[J]. Chinese Journal of Chemistry, 2022, 40(10), 1144-1148.
Authors:
Wang, Guan Jun
;
Zhang, Shu Yu
;
Sun, Zhen Liang
;
Li, Peng
;
Ding, Tong Mei
Favorite
|
TC[WOS]:
3
TC[Scopus]:
3
IF:
5.5
/
5.2
|
Submit date:2022/05/13
Alkylation
Asymmetric Synthesis
Enantioselectivity
Nitrogen Heterocycles
Quaternary Stereocenter
Distinct Crystal-Facet-Dependent Behaviors for Single-Atom Palladium-On-Ceria Catalysts: Enhanced Stabilization and Catalytic Properties
Journal article
Hu, Botao, Sun, Kaian, Zhuang, Zewen, Chen, Zheng, Liu, Shoujie, Cheong, Weng Chon, Chen, Cheng, Hu, Mingzhen, Cao, Xing, Ma, Junguo, Tu, Renyong, Zheng, Xusheng, Xiao, Hai, Chen, Xiao, Cui, Yi, Peng, Qing, Chen, Chen, Li, Yadong. Distinct Crystal-Facet-Dependent Behaviors for Single-Atom Palladium-On-Ceria Catalysts: Enhanced Stabilization and Catalytic Properties[J]. Advanced Materials, 2022, 34(16), 2107721.
Authors:
Hu, Botao
;
Sun, Kaian
;
Zhuang, Zewen
;
Chen, Zheng
;
Liu, Shoujie
; et al.
Favorite
|
TC[WOS]:
116
TC[Scopus]:
123
IF:
27.4
/
30.2
|
Submit date:2022/05/04
Crystal-facets
N-alkylation Reaction
Oxygen Defects, Pd–ceo 2
Single-atom Catalysis