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Sigma-1 receptor positive allosteric modulator promotes the neuronal survival and improves cognitive deficits in AD mice via Sigma-1 receptor/ERK pathway Conference paper
Xiaoyu Wang, Wenhua Zheng. Sigma-1 receptor positive allosteric modulator promotes the neuronal survival and improves cognitive deficits in AD mice via Sigma-1 receptor/ERK pathway[C], 2024.
Authors:  Xiaoyu Wang;  Wenhua Zheng
Favorite |  | Submit date：2024/08/31
Alzheimer's Disease, Somcl-668, Neuronal Cells, 3xtg-ad Mice, Sigma-1 Receptor/erk/creb Pathway  
Artemisinin protects against neural injury by targeting KEAP1 to inhibit ferroptosis in Alzheimer’s disease models Conference paper
Pengxi DENG, ZHENG WENHUA. Artemisinin protects against neural injury by targeting KEAP1 to inhibit ferroptosis in Alzheimer’s disease models[C], 2024.
Authors:  Pengxi DENG;  ZHENG WENHUA
Favorite |  | Submit date：2024/08/31
Artemisinin, Ferroptosis, Keap1, Nrf2, Alzheimer's Disease (Ad).  
Artemisinin Alleviates Astrocyte Over-Activation and Neuroinflammation by modulating the IRE1/NF-κB Signaling Pathway in in vitro and in vivo Alzheimer's Disease Models Conference paper
Lei Chen, ZHENG WENHUA. Artemisinin Alleviates Astrocyte Over-Activation and Neuroinflammation by modulating the IRE1/NF-κB Signaling Pathway in in vitro and in vivo Alzheimer's Disease Models[C], 2024.
Authors:  Lei Chen;  ZHENG WENHUA
Favorite |  | Submit date：2024/08/31
Alzheimer’s Disease  Endoplasmic Reticulum Stress  Artemisinin  Astrocyte  3xtg Ad Mice  Neuroinflammation  Ire1  Nf-κb.  
Artemisia annua Extract Improves the Cognitive Deficits and Reverses the Pathological Changes of Alzheimer’s Disease via Regulating YAP Signaling Journal article
Zhou,Wenshu, Lei,Bingxi, Yang,Chao, Silva,Marta, Xing,Xingan, Yu,Hua, Lu,Jiahong, Zheng,Wenhua. Artemisia annua Extract Improves the Cognitive Deficits and Reverses the Pathological Changes of Alzheimer’s Disease via Regulating YAP Signaling[J]. International Journal of Molecular Sciences, 2023, 24(6).
Authors:  Zhou,Wenshu;  Lei,Bingxi;  Yang,Chao;  Silva,Marta;  Xing,Xingan; et al.
Favorite | TC[WOS]:2 TC[Scopus]:3  IF:4.9/5.6 | Submit date：2023/08/03
Ad-type Pathologies  Alzheimer’s Disease  Artemisia Annua  Neuroprotective Effect  Yap Signaling Pathway  
Natural Carotenoids as Neuroprotective Agents for Alzheimer's Disease: An Evidence-Based Comprehensive Review Review article
2022
Authors:  Batool, Zahra;  Chen, Jie Hua;  Gao, Yao;  Lu, Louise Weiwei;  Xu, Haoxie; et al.
Favorite | TC[WOS]:8 TC[Scopus]:8  IF:5.7/6.0 | Submit date：2023/01/30
Alzheimer's Disease (Ad)  Adjuvant Therapy  Carotenoids  Natural Compounds  Dementia  
Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models Journal article
Iyaswamy, Ashok, Wang, Xueli, Krishnamoorthi, Senthilkumar, Kaliamoorthy, Venkatapathy, Sreenivasmurthy, Sravan G., Kumar Durairajan, Siva Sundara, Song, Ju Xian, Tong, Benjamin Chun kit, Zhu, Zhou, Su, Cheng Fu, Liu, Jia, Cheung, King Ho, Lu, Jia Hong, Tan, Jie Qiong, Li, Hung Wing, Wong, Man Shing, Li, Min. Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models[J]. Redox Biology, 2022, 51, 102280.
Authors:  Iyaswamy, Ashok;  Wang, Xueli;  Krishnamoorthi, Senthilkumar;  Kaliamoorthy, Venkatapathy;  Sreenivasmurthy, Sravan G.; et al.
Favorite | TC[WOS]:48 TC[Scopus]:51  IF:10.7/11.7 | Submit date：2022/05/13
Theranostic  Alzheimer’s Disease  Aβ-targeting  Aβ-aggregate Inhibition  3xtg-ad  5xfad  
Impairment of the autophagy–lysosomal pathway in Alzheimer's diseases: Pathogenic mechanisms and therapeutic potential Journal article
Wei Zhang, Chengchao Xu, Jichao Sun, Han-Ming Shen, Jigang Wang, Chuanbin Yang. Impairment of the autophagy–lysosomal pathway in Alzheimer's diseases: Pathogenic mechanisms and therapeutic potential[J]. Acta Pharmaceutica Sinica B, 2022, 12(3), 1019-1040.
Authors:  Wei Zhang;  Chengchao Xu;  Jichao Sun;  Han-Ming Shen;  Jigang Wang; et al.
Favorite | TC[WOS]:82 TC[Scopus]:84  IF:14.7/14.1 | Submit date：2022/04/06
Alzheimer’s Disease (Ad)  Amyloid Beta (Ab) Peptides  Mapt/tau  Autophagy–lysosomal Pathway  Autophagy Enhancers  Autophagy  Mitophagy  Neurodegenerative Diseases  
Artemisia annua extracts improve the cognitive deficits and reverse the pathological changes of Alzheimer’s disease via regulating YAP signaling Conference paper
Zheng, W.. Artemisia annua extracts improve the cognitive deficits and reverse the pathological changes of Alzheimer’s disease via regulating YAP signaling[C], 2021.
Authors:  Zheng, W.
Favorite |  | Submit date：2022/08/31
Alzheimer's Disease  Artemisia Annua Extracts  Neuronal Apoptosis  Ad Type Pathologies  Yap Signaling Pathway  
Artemisia annua extracts improve the cognitive deficits and reverse the pathological changes of Alzheimer’s disease via regulating YAP signaling Conference paper
Zheng, W.. Artemisia annua extracts improve the cognitive deficits and reverse the pathological changes of Alzheimer’s disease via regulating YAP signaling[C], 2021.
Authors:  Zheng, W.
Favorite |  | Submit date：2022/08/31
Alzheimer's Disease  Artemisia Annua Extracts  Neuronal Apoptosis  Ad-type Pathologies  Yap Signaling Pathway  
The protective effect of artemisinin against hydrogen peroxide-induced oxidative injury in SH-SY5Y and hippocampal neurons via the activation of AMPK Conference paper
Zheng, W.. The protective effect of artemisinin against hydrogen peroxide-induced oxidative injury in SH-SY5Y and hippocampal neurons via the activation of AMPK[C], 2021.
Authors:  Zheng, W.
Favorite |  | Submit date：2022/08/31
Oxidative Stress  Alzheimer's Disease (Ad)  Sh-sy5y Cells  Ampk