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Novel C. elegans models of Lewy body disease reveal pathological protein interactions and widespread miRNA dysregulation Journal article
Li, Rongzhen, Huang, Xiaobing, Shen, Linjing, Zhang, Tianjiao, Liu, Ning, Hou, Xiangqing, Wong, Garry. Novel C. elegans models of Lewy body disease reveal pathological protein interactions and widespread miRNA dysregulation[J]. Cellular and Molecular Life Sciences, 2024, 81(1), 377.
Authors:  Li, Rongzhen;  Huang, Xiaobing;  Shen, Linjing;  Zhang, Tianjiao;  Liu, Ning; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:6.2/7.7 | Submit date：2024/10/10
Amyloid β  Parkinson’s Disease  Tar-dna-binding Protein 43  Tau Protein  Α-synuclein  
Tetramethylpyrazine Nitrone (TBN) Reduces Amyloid β Deposition in Alzheimer’s Disease Models by Modulating APP Expression, BACE1 Activity, and Autophagy Pathways Journal article
Zhou, Xinhua, Zhu, Zeyu, Kuang, Shaoming, Huang, Kaipeng, Li, Yueping, Wang, Yuqiang, Chen, Haiyun, Hoi, Maggie Pui Man, Xu, Benhong, Yang, Xifei, Zhang, Zaijun. Tetramethylpyrazine Nitrone (TBN) Reduces Amyloid β Deposition in Alzheimer’s Disease Models by Modulating APP Expression, BACE1 Activity, and Autophagy Pathways[J]. Pharmaceuticals, 2024, 17(8), 1005.
Authors:  Zhou, Xinhua;  Zhu, Zeyu;  Kuang, Shaoming;  Huang, Kaipeng;  Li, Yueping; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:4.3/4.6 | Submit date：2024/10/10
Amyloid Precursor Protein  Amyloid β  Microrna  
Emerging roles of astrocytes in blood-brain barrier disruption upon amyloid-beta insults in Alzheimer's disease Review article
2023
Authors:  Yue,Qian;  Hoi,Maggie Pui Man
Favorite | TC[WOS]:23 TC[Scopus]:22  IF:5.9/5.2 | Submit date：2023/08/03
Alzheimer's Disease  Amyloid-beta  Astrocyte (Astroglial)-endothelial Interaction  Astrocyte Pathology  Blood-brain Barrier  Blood-brain Barrier Disruption  Brain Endothelial Cell  Neuroinflammation  Reactive Astrocyte  
Emerging roles of astrocytes in blood-brain barrier disruption upon amyloid-beta insults in Alzheimer's disease Journal article
Yue, Qian, Hoi, Maggie Pui Man. Emerging roles of astrocytes in blood-brain barrier disruption upon amyloid-beta insults in Alzheimer's disease[J]. Neural Regeneration Research, 2023, 18(9), 1890-1902.
Authors:  Yue, Qian;  Hoi, Maggie Pui Man
Favorite | TC[WOS]:23 TC[Scopus]:22  IF:5.9/5.2 | Submit date：2024/01/10
Alzheimer's disease  amyloid-beta  astrocyte (astroglial)-endothelial interaction  astrocyte pathology  blood-brain barrier  blood-brain barrier disruption  brain endothelial cell  neuroinflammation  reactive astrocyte  
Evaluations of the neuroprotective effects of a dual-target isoquinoline inhibitor in the triple transgenic mouse model of Alzheimer's disease Journal article
Wei, Rong, He, Jun Qiu, Chen, Wen Hua, Tam, Kin Yip. Evaluations of the neuroprotective effects of a dual-target isoquinoline inhibitor in the triple transgenic mouse model of Alzheimer's disease[J]. Neuroscience Letters, 2023, 802, 137166.
Authors:  Wei, Rong;  He, Jun Qiu;  Chen, Wen Hua;  Tam, Kin Yip
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:2.5/2.5 | Submit date：2023/05/02
Alzheimer's Disease  Dual-target Inhibitor  Apoptosis  Amyloid Plaque  Early Stage Disease  
Evaluation of therapeutic effects of tetramethylpyrazine nitrone in Alzheimer’s disease mouse model and proteomics analysis Journal article
Xinhua Zhou, Kaipeng Huang, Yuqiang Wang, Zaijun Zhang, Yingying Liu, Qinghua Hou, Xifei Yang, Maggie Pui Man Hoi. Evaluation of therapeutic effects of tetramethylpyrazine nitrone in Alzheimer’s disease mouse model and proteomics analysis[J]. Frontiers in Pharmacology, 2023, 14, 1082602.
Authors:  Xinhua Zhou;  Kaipeng Huang;  Yuqiang Wang;  Zaijun Zhang;  Yingying Liu; et al.
Favorite | TC[WOS]:10 TC[Scopus]:10  IF:4.4/5.0 | Submit date：2023/08/03
Alhzheimer Disease  Amyloid Beta  Pink1  Proteomic Analysis  Tetramethylpyrazine Nitrone  
Atomic zinc sites with hierarchical porous carbon for high-throughput chemical screening with high loading capacity and stability Journal article
Zhou, Mingyue, Wu, Xuan, Li, Yan, Zhang, Huixia, Liu, Qinghua, Song, Linlin, Wang, Caiyun, Law, Betty Yuen Kwan, Jiang, Zhihong, Zhang, Wei. Atomic zinc sites with hierarchical porous carbon for high-throughput chemical screening with high loading capacity and stability[J]. Pharmacological Research, 2022, 178.
Authors:  Zhou, Mingyue;  Wu, Xuan;  Li, Yan;  Zhang, Huixia;  Liu, Qinghua; et al.
Favorite | TC[WOS]:1 TC[Scopus]:3  IF:9.1/9.0 | Submit date：2023/01/30
Amyloid Β-peptides  Atomic Zinc Sites  Bisdemethoxycurcumin (Pubchem Cid: 5315472)  Curcumenol (Pubchem Cid: 167812)  Curcumin (Pubchem Cid: 969516)  Curcumol (Pubchem Cid: 14240392)  Demethoxycurcumin (Pubchem Cid: 5469424)  Furanodiene (Pubchem Cid: 636458)  Hierarchical Porous Carbon  Ligand Fishing  Turmeric  
Roles of Serum Amyloid A 1 Protein Isoforms in Rheumatoid Arthritis Journal article
Elaine Lai-Han Leung, Lai, Huan Ling, Li, Run Ze, Pan, Hu Dan, Jiang, Ze Bo, Li, Ying, Duan, Fu Gang, Xu, Jia Hui, Zhang, Yi Zhong, Shi, A. Xi, Wei, Chun Li, Zhang, Fang Yuan, Yao, Xiao Jun, Liu, Liang. Roles of Serum Amyloid A 1 Protein Isoforms in Rheumatoid Arthritis[J]. Engineering, 2022, 10, 174-182.
Authors:  Elaine Lai-Han Leung;  Lai, Huan Ling;  Li, Run Ze;  Pan, Hu Dan;  Jiang, Ze Bo; et al.
Favorite | TC[WOS]:0 TC[Scopus]:3  IF:10.1/11.6 | Submit date：2023/01/30
Intra-articular  Pathogenetic  Rheumatoid Arthritis  Serum Amyloid a 1  
Impairment of the autophagy–lysosomal pathway in Alzheimer's diseases: Pathogenic mechanisms and therapeutic potential Journal article
Wei Zhang, Chengchao Xu, Jichao Sun, Han-Ming Shen, Jigang Wang, Chuanbin Yang. Impairment of the autophagy–lysosomal pathway in Alzheimer's diseases: Pathogenic mechanisms and therapeutic potential[J]. Acta Pharmaceutica Sinica B, 2022, 12(3), 1019-1040.
Authors:  Wei Zhang;  Chengchao Xu;  Jichao Sun;  Han-Ming Shen;  Jigang Wang; et al.
Favorite | TC[WOS]:82 TC[Scopus]:84  IF:14.7/14.1 | Submit date：2022/04/06
Alzheimer’s Disease (Ad)  Amyloid Beta (Ab) Peptides  Mapt/tau  Autophagy–lysosomal Pathway  Autophagy Enhancers  Autophagy  Mitophagy  Neurodegenerative Diseases  
Murine Beta-Amyloid (1–42) Oligomers Disrupt Endothelial Barrier Integrity and VEGFR Signaling via Activating Astrocytes to Release Deleterious Soluble Factors Journal article
Yue, Qian, Zhou, Xinhua, Zhang, Zaijun, Hoi, Maggie Pui Man. Murine Beta-Amyloid (1–42) Oligomers Disrupt Endothelial Barrier Integrity and VEGFR Signaling via Activating Astrocytes to Release Deleterious Soluble Factors[J]. International Journal of Molecular Sciences, 2022, 23(3), 1878.
Authors:  Yue, Qian;  Zhou, Xinhua;  Zhang, Zaijun;  Hoi, Maggie Pui Man
Favorite | TC[WOS]:9 TC[Scopus]:11 | Submit date：2022/03/04
Astrocytes  Blood–brain Barrier  Endothelial Cells  Murine Amyloid-beta  Tight Junctions  Vegfr2 Signaling Pathway