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Emerging roles of astrocytes in blood-brain barrier disruption upon amyloid-beta insults in Alzheimer's disease Journal article
Yue, Qian, Hoi, Maggie Pui Man. Emerging roles of astrocytes in blood-brain barrier disruption upon amyloid-beta insults in Alzheimer's disease[J]. Neural Regeneration Research, 2023, 18(9), 1890-1902.
Authors:  Yue, Qian;  Hoi, Maggie Pui Man
Favorite | TC[WOS]:23 TC[Scopus]:21  IF:5.9/5.2 | Submit date:2024/01/10
Alzheimer's disease  amyloid-beta  astrocyte (astroglial)-endothelial interaction  astrocyte pathology  blood-brain barrier  blood-brain barrier disruption  brain endothelial cell  neuroinflammation  reactive astrocyte  
Emerging roles of astrocytes in blood-brain barrier disruption upon amyloid-beta insults in Alzheimer's disease Review article
2023
Authors:  Yue,Qian;  Hoi,Maggie Pui Man
Favorite | TC[WOS]:23 TC[Scopus]:21  IF:5.9/5.2 | Submit date:2023/08/03
Alzheimer's Disease  Amyloid-beta  Astrocyte (Astroglial)-endothelial Interaction  Astrocyte Pathology  Blood-brain Barrier  Blood-brain Barrier Disruption  Brain Endothelial Cell  Neuroinflammation  Reactive Astrocyte  
Evaluation of therapeutic effects of tetramethylpyrazine nitrone in Alzheimer’s disease mouse model and proteomics analysis Journal article
Xinhua Zhou, Kaipeng Huang, Yuqiang Wang, Zaijun Zhang, Yingying Liu, Qinghua Hou, Xifei Yang, Maggie Pui Man Hoi. Evaluation of therapeutic effects of tetramethylpyrazine nitrone in Alzheimer’s disease mouse model and proteomics analysis[J]. Frontiers in Pharmacology, 2023, 14, 1082602.
Authors:  Xinhua Zhou;  Kaipeng Huang;  Yuqiang Wang;  Zaijun Zhang;  Yingying Liu; et al.
Favorite | TC[WOS]:10 TC[Scopus]:10  IF:4.4/5.0 | Submit date:2023/08/03
Alhzheimer Disease  Amyloid Beta  Pink1  Proteomic Analysis  Tetramethylpyrazine Nitrone  
Impairment of the autophagy–lysosomal pathway in Alzheimer's diseases: Pathogenic mechanisms and therapeutic potential Journal article
Wei Zhang, Chengchao Xu, Jichao Sun, Han-Ming Shen, Jigang Wang, Chuanbin Yang. Impairment of the autophagy–lysosomal pathway in Alzheimer's diseases: Pathogenic mechanisms and therapeutic potential[J]. Acta Pharmaceutica Sinica B, 2022, 12(3), 1019-1040.
Authors:  Wei Zhang;  Chengchao Xu;  Jichao Sun;  Han-Ming Shen;  Jigang Wang; et al.
Favorite | TC[WOS]:80 TC[Scopus]:83  IF:14.7/14.1 | Submit date:2022/04/06
Alzheimer’s Disease (Ad)  Amyloid Beta (Ab) Peptides  Mapt/tau  Autophagy–lysosomal Pathway  Autophagy Enhancers  Autophagy  Mitophagy  Neurodegenerative Diseases  
Murine Beta-Amyloid (1–42) Oligomers Disrupt Endothelial Barrier Integrity and VEGFR Signaling via Activating Astrocytes to Release Deleterious Soluble Factors Journal article
Yue, Qian, Zhou, Xinhua, Zhang, Zaijun, Hoi, Maggie Pui Man. Murine Beta-Amyloid (1–42) Oligomers Disrupt Endothelial Barrier Integrity and VEGFR Signaling via Activating Astrocytes to Release Deleterious Soluble Factors[J]. International Journal of Molecular Sciences, 2022, 23(3), 1878.
Authors:  Yue, Qian;  Zhou, Xinhua;  Zhang, Zaijun;  Hoi, Maggie Pui Man
Favorite | TC[WOS]:9 TC[Scopus]:10 | Submit date:2022/03/04
Astrocytes  Blood–brain Barrier  Endothelial Cells  Murine Amyloid-beta  Tight Junctions  Vegfr2 Signaling Pathway  
Oxyphylla A ameliorates cognitive deficits and alleviates neuropathology via the Akt-GSK3β and Nrf2-Keap1-HO-1 pathways in vitro and in vivo murine models of Alzheimer's disease Journal article
Bian, Yaqi, Chen, Yan, Wang, Xiufen, Cui, Guozhen, Ung, Carolina Oi Lam, Lu, Jia Hong, Cong, Weihong, Tang, Benqin, Lee, Simon Ming Yuen. Oxyphylla A ameliorates cognitive deficits and alleviates neuropathology via the Akt-GSK3β and Nrf2-Keap1-HO-1 pathways in vitro and in vivo murine models of Alzheimer's disease[J]. Journal of Advanced Research, 2021, 34, 1-12.
Authors:  Bian, Yaqi;  Chen, Yan;  Wang, Xiufen;  Cui, Guozhen;  Ung, Carolina Oi Lam; et al.
Favorite | TC[WOS]:51 TC[Scopus]:53  IF:11.4/11.0 | Submit date:2022/05/13
Alzheimer's Disease  Amyloid Beta Proteins  Oxidative Stress  Oxyphylla a  Samp8  
Tetramethylpyrazine nitrone (TBN), derivative from traditional Chinese medicine Chuan Xiong exerted a protective effect on neurovascular unit against mural amyloid-beta1-42 oligomers Conference paper
Qian, E., Hoi, P. M.. Tetramethylpyrazine nitrone (TBN), derivative from traditional Chinese medicine Chuan Xiong exerted a protective effect on neurovascular unit against mural amyloid-beta1-42 oligomers[C], 2021.
Authors:  Qian, E.;  Hoi, P. M.
Favorite |  | Submit date:2022/08/10
TCM  neurovascular unit  amyloid beta  
Artemisinin improved Aβ- related pathological features and cognitive function of Alzheimer's disease Conference paper
Zhao, X., Zheng, W.. Artemisinin improved Aβ- related pathological features and cognitive function of Alzheimer's disease[C], 2020, 84-85.
Authors:  Zhao, X.;  Zheng, W.
Favorite |  | Submit date:2022/08/31
Alzheimer's Disease  Artemisinin  Cognitive Behavior  Amyloid Beta  3×tg-ad Mouse  Sh-sy5ycells  
An Isoquinolinium Dual Inhibitor of Cholinesterases and Amyloid β Aggregation Mitigates Neuropathological Changes in a Triple-Transgenic Mouse Model of Alzheimer's Disease Journal article
Ju,Yaojun, Chakravarty,Harapriya, Tam,Kin Yip. An Isoquinolinium Dual Inhibitor of Cholinesterases and Amyloid β Aggregation Mitigates Neuropathological Changes in a Triple-Transgenic Mouse Model of Alzheimer's Disease[J]. ACS Chemical Neuroscience, 2020, 11(20), 3346-3357.
Authors:  Ju,Yaojun;  Chakravarty,Harapriya;  Tam,Kin Yip
Favorite | TC[WOS]:6 TC[Scopus]:6  IF:4.1/4.3 | Submit date:2021/03/04
Alzheimer's Disease  Amyloid Beta  Cholinesterase  Dual Inhibition  
9R, the cholinesterase and amyloid beta aggregation dual inhibitor, as a multifunctional agent to improve cognitive deficit and neuropathology in the triple-transgenic Alzheimer's disease mouse model Journal article
Ju,Yaojun, Tam,Kin Yip. 9R, the cholinesterase and amyloid beta aggregation dual inhibitor, as a multifunctional agent to improve cognitive deficit and neuropathology in the triple-transgenic Alzheimer's disease mouse model[J]. Neuropharmacology, 2020, 181, 108354.
Authors:  Ju,Yaojun;  Tam,Kin Yip
Favorite | TC[WOS]:9 TC[Scopus]:9  IF:4.6/4.5 | Submit date:2021/03/04
Cholinesterase  Amyloid Beta  Dual Inhibition  Multifunction  Alzheimer's Disease