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Isoalantolactone/hydroxamic acid hybrids as potent dual STAT3/HDAC inhibitors and self-assembled nanoparticles for cancer therapy Journal article
Mo, Hualong, Liu, Jie Ying, Su, Zhengxi, Zhao, Deng Gao, Ma, Yan Yan, Zhang, Kun, Wang, Qi, Fu, Chun, Wang, Yao, Chen, Meiwan, Hu, Burong. Isoalantolactone/hydroxamic acid hybrids as potent dual STAT3/HDAC inhibitors and self-assembled nanoparticles for cancer therapy[J]. European Journal of Medicinal Chemistry, 2024, 277, 116765.
Authors:  Mo, Hualong;  Liu, Jie Ying;  Su, Zhengxi;  Zhao, Deng Gao;  Ma, Yan Yan; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:6.0/6.1 | Submit date：2024/09/03
Antitumor  Hdac  Isoalantolactone  Self-assembled Nanoparticles  Stat3  
Anti-TNFR2 enhanced the antitumor activity of a new HMGN1/3M-052 stimulated dendritic cell vaccine in a mouse model of colon cancer Journal article
Zhu, Lan, Zhang, Xiangyan, Chen, Xin, Yang, De, Nie, Yujie, Pan, Runsang, Li, Linzhao, Wang, Chenglv, Gui, Huan, Chen, Shuanghui, Jing, Qianyu, Wang, Mengjiao, Nie, Yingjie. Anti-TNFR2 enhanced the antitumor activity of a new HMGN1/3M-052 stimulated dendritic cell vaccine in a mouse model of colon cancer[J]. Biochemical and Biophysical Research Communications, 2023, 653, 106-114.
Authors:  Zhu, Lan;  Zhang, Xiangyan;  Chen, Xin;  Yang, De;  Nie, Yujie; et al.
Favorite | TC[WOS]:6 TC[Scopus]:5  IF:2.5/2.7 | Submit date：2023/05/02
Anti-tnfr2  Antitumor  cd4+foxp3+regulatory t Cells (Tregs)  Dendritic Cells (Dcs)  Hmgn1 And 3m-052  Immunotherapy  
A lymphatic route for a hyperbranched heteroglycan from Radix Astragali to trigger immune responses after oral dosing Journal article
Zhang, Quanwei, Li, Lifeng, Hao, Shuang, Liu, Man, Huo, Chuying, Wu, Jianjun, Liu, Hongbing, Bao, Wanrong, Zheng, Hongming, Li, Zhipeng, Cheng, Huiyuan, Fung, Hauyee, Wong, Tinlong, Leung, Pingchung, Wang, Shunchun, Li, Ting, Zhang, Ge, Li, Min, Zhao, Zhongzhen, Jia, Wei, Bian, Zhaoxiang, Mitchison, Timothy, Zhang, Jingchao, Lyu, Aiping, Han, Quanbin, Sun, Handong. A lymphatic route for a hyperbranched heteroglycan from Radix Astragali to trigger immune responses after oral dosing[J]. Carbohydrate Polymers, 2022, 292.
Authors:  Zhang, Quanwei;  Li, Lifeng;  Hao, Shuang;  Liu, Man;  Huo, Chuying; et al.
Favorite | TC[WOS]:10 TC[Scopus]:11  IF:10.7/10.2 | Submit date：2023/01/30
Antitumor Immune Responses  Intact  Polysaccharide  Radix Astragali  Targeting Route  
Design, synthesis and antitumor evaluation of novel 1H-indole-2-carboxylic acid derivatives targeting 14-3-3η protein Journal article
Gao, Zhenxiong, Fan, Tingting, Chen, Linbo, Yang, Mengchu, Wai Wong, Vincent Kam, Chen, Dawei, Liu, Zijian, Zhou, Yaoyao, Wu, Weibin, Qiu, Zixuan, Zhang, Cunlong, Li, Yuan, Jiang, Yuyang. Design, synthesis and antitumor evaluation of novel 1H-indole-2-carboxylic acid derivatives targeting 14-3-3η protein[J]. European Journal of Medicinal Chemistry, 2022, 238.
Authors:  Gao, Zhenxiong;  Fan, Tingting;  Chen, Linbo;  Yang, Mengchu;  Wai Wong, Vincent Kam; et al.
Favorite | TC[WOS]:3 TC[Scopus]:3  IF:6.0/6.1 | Submit date：2023/01/30
14-3-3η Protein  Antitumor Bioactivity  Drug Design  Hepatocellular Carcinoma  Novel Target  
Extraction, purification, structural features and biological activities of longan fruit pulp (Longyan) polysaccharides: A review Review article
2022
Authors:  Xuan Yue;  Zhejie Chen;  Jinming Zhang;  Chi Huang;  Shiyi Zhao; et al.
Favorite | TC[WOS]:12 TC[Scopus]:11  IF:4.0/4.4 | Submit date：2023/01/30
Antitumor  Bioactivities  Extraction  Immune Regulation  Longan Fruit Pulp Polysaccharide  Structures  
Reactive oxygen species activated by mitochondria-specific camptothecin prodrug for enhanced chemotherapy Journal article
Guo, Zhaopei, Wang, Zian, Liang, Ruifeng, Tian, Huayu, Chen, Xuesi, Chen, Meiwan. Reactive oxygen species activated by mitochondria-specific camptothecin prodrug for enhanced chemotherapy[J]. Bosnian Journal of Basic Medical Sciences, 2022, 22(6), 934-948.
Authors:  Guo, Zhaopei;  Wang, Zian;  Liang, Ruifeng;  Tian, Huayu;  Chen, Xuesi; et al.
Favorite | TC[WOS]:4 TC[Scopus]:4  IF:3.1/3.3 | Submit date：2022/08/29
Camptothecin Prodrug  Reactive Oxygen Species  Antitumor Therapy  
Antitumor Activities of tRNA-Derived Fragments and tRNA Halves from Non-pathogenic Escherichia coli Strains on Colorectal Cancer and Their Structure-Activity Relationship Journal article
Cao, Kai Yue, Pan, Yu, Yan, Tong Meng, Tao, Peng, Xiao, Yi, Jiang, Zhi Hong. Antitumor Activities of tRNA-Derived Fragments and tRNA Halves from Non-pathogenic Escherichia coli Strains on Colorectal Cancer and Their Structure-Activity Relationship[J]. mSystems, 2022, 7(2).
Authors:  Cao, Kai Yue;  Pan, Yu;  Yan, Tong Meng;  Tao, Peng;  Xiao, Yi; et al.
Favorite | TC[WOS]:10 TC[Scopus]:11  IF:5.0/6.1 | Submit date：2023/01/30
Antitumor Activity  Chemical Modifications  Gut Microbiota  Trf  
Orchestrated Yolk–Shell Nanohybrids Regulate Macrophage Polarization and Dendritic Cell Maturation for Oncotherapy with Augmented Antitumor Immunity Journal article
Zhao, Xiaoyi, Guo, Kangli, Zhang, Kai, Duan, Shun, Chen, Meiwan, Zhao, Nana, Xu, Fu Jian. Orchestrated Yolk–Shell Nanohybrids Regulate Macrophage Polarization and Dendritic Cell Maturation for Oncotherapy with Augmented Antitumor Immunity[J]. Advanced Materials, 2022, 34(9), 2108263.
Authors:  Zhao, Xiaoyi;  Guo, Kangli;  Zhang, Kai;  Duan, Shun;  Chen, Meiwan; et al.
Favorite | TC[WOS]:68 TC[Scopus]:74  IF:27.4/30.2 | Submit date：2022/03/28
Antitumor Immunity  Chemodynamic Therapy  Immunomodulatory Effect  Tumor Microenvironment  Yolk–shell Structure  
Methylaervine as Potential Lead Compound Against Cervical Carcinoma: Pharmacologic Mechanism Prediction based on Network Pharmacology Journal article
Dan, Wenjia, Xu, Yujie, Gu, Hongling, Gao, Jixiang, Dai, Jiangkun. Methylaervine as Potential Lead Compound Against Cervical Carcinoma: Pharmacologic Mechanism Prediction based on Network Pharmacology[J]. Current Computer-Aided Drug Design, 2022, 18(1), 73-80.
Authors:  Dan, Wenjia;  Xu, Yujie;  Gu, Hongling;  Gao, Jixiang;  Dai, Jiangkun
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:1.5/1.5 | Submit date：2022/03/28
Methylaervine  Synthesis  Antitumor Activity  Adme Study  Network Pharmacology  Docking  
A TNFR2 antibody by countering immunosuppression cooperates with HMGN1 and R848 immune stimulants to inhibit murine colon cancer Journal article
Jiang, Mengmeng, Liu, Jia, Yang, De, Tross, Debra, Li, Ping, Chen, Fengyang, Alam, Md Masud, Faustman, Denise L., Oppenheim, Joost J., Chen, Xin. A TNFR2 antibody by countering immunosuppression cooperates with HMGN1 and R848 immune stimulants to inhibit murine colon cancer[J]. International Immunopharmacology, 2021, 101, 108345.
Authors:  Jiang, Mengmeng;  Liu, Jia;  Yang, De;  Tross, Debra;  Li, Ping; et al.
Favorite | TC[WOS]:22 TC[Scopus]:22  IF:4.8/5.0 | Submit date：2021/12/08
Antitumor  cd4+foxp3+ Regulatory t Cells (Tregs)  Hmgn1 And R848  Immunotherapy  Tnfr2