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Rupatadine inhibits colorectal cancer cell proliferation through the PIP5K1A/Akt/CDK2 pathway Journal article
Jiang, Lei, Zhang, Zhibo, Luo, Zhaofeng, Li, Luan, Yuan, Shengtao, Cui, Min, He, Ke, Xiao, Jing. Rupatadine inhibits colorectal cancer cell proliferation through the PIP5K1A/Akt/CDK2 pathway[J]. Biomedicine and Pharmacotherapy, 2024, 176, 116826.
Authors:  Jiang, Lei;  Zhang, Zhibo;  Luo, Zhaofeng;  Li, Luan;  Yuan, Shengtao; et al.
Favorite | TC[WOS]:0 TC[Scopus]:1  IF:6.9/6.8 | Submit date：2024/07/04
Cell Cycle  Cell Proliferation  Colorectal Cancer  Pip5k1a  Rupatadine  
αO-Conotoxin GeXIVA[1,2] Suppresses In Vivo Tumor Growth of Triple-Negative Breast Cancer by Inhibiting AKT-mTOR, STAT3 and NF-κB Signaling Mediated Proliferation and Inducing Apoptosis Journal article
Guo, Xijun, He, Leping, Xu, Weifeng, Wang, Wanrong, Feng, Xiaoli, Fu, Yuanfeng, Zhang, Xiaofan, Ding, Ren Bo, Qi, Xingzhu, Bao, Jiaolin, Luo, Sulan. αO-Conotoxin GeXIVA[1,2] Suppresses In Vivo Tumor Growth of Triple-Negative Breast Cancer by Inhibiting AKT-mTOR, STAT3 and NF-κB Signaling Mediated Proliferation and Inducing Apoptosis[J]. Marine Drugs, 2024, 22(6), 252.
Authors:  Guo, Xijun;  He, Leping;  Xu, Weifeng;  Wang, Wanrong;  Feng, Xiaoli; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:4.9/5.2 | Submit date：2024/08/05
Apoptosis  Breast Cancer  Gexiva[1,2]  Proliferation  Αo-conotoxin  
Repurposing Sertraline for the Treatment of Colorectal Cancer by Blocking Autophagic Flux and Inhibiting Tumor Proliferation Journal article
He, Leping, Guo, Xijun, Wang, Wanrong, Xu, Weifeng, Feng, Xiaoli, Fu, Yuanfeng, Tian, Yuxi, He, Zongmao, Luo, Sulan, Bao, Jiaolin, Ding, Ren Bo. Repurposing Sertraline for the Treatment of Colorectal Cancer by Blocking Autophagic Flux and Inhibiting Tumor Proliferation[J]. Advanced Therapeutics, 2024.
Authors:  He, Leping;  Guo, Xijun;  Wang, Wanrong;  Xu, Weifeng;  Feng, Xiaoli; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:3.7/4.7 | Submit date：2024/09/03
Autolysosomal Degradation  Autophagic Flux  Colorectal Cancer  Proliferation  Sertraline  
Effects of Cinobufagin on the Proliferation, Migration, and Invasion of H1299 Lung Cancer Cells Journal article
Mingna Sun, Dongyu Huang, Yun Liu, Haifang Chen, Hua Yu, Guobin Zhang, Qilei Chen, Hubiao Chen, Jianye Zhang. Effects of Cinobufagin on the Proliferation, Migration, and Invasion of H1299 Lung Cancer Cells[J]. Chemistry and Biodiversity, 2022, 20(1), e202200961.
Authors:  Mingna Sun;  Dongyu Huang;  Yun Liu;  Haifang Chen;  Hua Yu; et al.
Favorite | TC[WOS]:0 TC[Scopus]:3  IF:2.3/2.5 | Submit date：2023/02/08
Cinobufagin  H1299 Cell  Lung Cancer  Metastasis  Proliferation  
Synthesis, biological evaluation and structure-activity relationship of novel dichloroacetophenones targeting pyruvate dehydrogenase kinases with potent anticancer activity Journal article
Xu,Biao, Wang,Zhi Peng, Liu,Qingwang, Yang,Xiaohong, Li,Xuemin, Huang,Ding, Qiu,Yanfei, Tam,Kin Yip, Zhang,Shao Lin, He,Yun. Synthesis, biological evaluation and structure-activity relationship of novel dichloroacetophenones targeting pyruvate dehydrogenase kinases with potent anticancer activity[J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 214, 113225.
Authors:  Xu,Biao;  Wang,Zhi Peng;  Liu,Qingwang;  Yang,Xiaohong;  Li,Xuemin; et al.
Favorite | TC[WOS]:10 TC[Scopus]:9  IF:6.0/6.1 | Submit date：2021/03/04
Cancer Metabolism  Proliferation  Pyruvate Dehydrogenase Kinase  Structure-activity Relationship  
Development of dual inhibitors targeting pyruvate dehydrogenase kinases and human lactate dehydrogenase A: High-throughput virtual screening, synthesis and biological validation Journal article
Xiang,Sichuan, Huang,Ding, He,Qiaolin, Li,Jie, Tam,Kin Yip, Zhang,Shao Lin, He,Yun. Development of dual inhibitors targeting pyruvate dehydrogenase kinases and human lactate dehydrogenase A: High-throughput virtual screening, synthesis and biological validation[J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 203, 112579.
Authors:  Xiang,Sichuan;  Huang,Ding;  He,Qiaolin;  Li,Jie;  Tam,Kin Yip; et al.
Favorite | TC[WOS]:13 TC[Scopus]:14  IF:6.0/6.1 | Submit date：2021/03/04
Cancer Metabolism  Cancer Proliferation  Dual Inhibitor  Lactate Dehydrogenase a  Pyruvate Dehydrogenase Kinase  
Ethanol extract of Ophiorrhiza pumila suppresses liver cancer cell proliferation and migration Journal article
Liu,Hui, Liao,Wanqin, Fan,Lixia, Zheng,Zhaoguang, Liu,Dahai, Zhang,Qing Wen, Yang,Anping, Liu,Fang. Ethanol extract of Ophiorrhiza pumila suppresses liver cancer cell proliferation and migration[J]. Chinese Medicine, 2020, 15(1), 11.
Authors:  Liu,Hui;  Liao,Wanqin;  Fan,Lixia;  Zheng,Zhaoguang;  Liu,Dahai; et al.
Favorite | TC[WOS]:13 TC[Scopus]:16  IF:5.3/5.5 | Submit date：2021/03/02
Ophiorrhiza Pumila  Liver Cancer  Proliferation  Apoptosis  Migration  
DNA replication licensing proteins: Saints and sinners in cancer Journal article
Mughal,Muhammad Jameel, Mahadevappa,Ravikiran, Kwok,Hang Fai. DNA replication licensing proteins: Saints and sinners in cancer[J]. Seminars in Cancer Biology, 2019, 58, 11-21.
Authors:  Mughal,Muhammad Jameel;  Mahadevappa,Ravikiran;  Kwok,Hang Fai
Favorite | TC[WOS]:31 TC[Scopus]:31  IF:12.1/13.2 | Submit date：2021/03/04
Dna Replication  Licensing Proteins  Cancer  Proliferation  Pre-replication Complex  
Warburg Effects in Cancer and Normal Proliferating Cells: Two Tales of the Same Name Journal article
Sun, Huiyan, Chen, Liang, Cao, Sha, Liang, Yanchun, Xu, Ying. Warburg Effects in Cancer and Normal Proliferating Cells: Two Tales of the Same Name[J]. Genomics, Proteomics and Bioinformatics, 2019, 17(3), 273-286.
Authors:  Sun, Huiyan;  Chen, Liang;  Cao, Sha;  Liang, Yanchun;  Xu, Ying
Favorite | TC[WOS]:36 TC[Scopus]:41  IF:11.5/10.3 | Submit date：2022/05/17
Cancer  Cell Proliferation  Fenton Reaction  Ph Homeostasis  Warburg Effect  
DNA replication licensing protein MCM10 promotes tumor progression and is a novel prognostic biomarker and potential therapeutic target in breast cancer Journal article
Mahadevappa R., Neves H., Yuen S.M., Jameel M., Bai Y., Yuen H.-F., Zhang S.-D., Zhu Y., Lin Y., Kwok H.F.. DNA replication licensing protein MCM10 promotes tumor progression and is a novel prognostic biomarker and potential therapeutic target in breast cancer[J]. Cancers, 2018, 10(9).
Authors:  Mahadevappa R.;  Neves H.;  Yuen S.M.;  Jameel M.;  Bai Y.; et al.
Favorite | TC[WOS]:32 TC[Scopus]:32 | Submit date：2018/12/19
Breast Cancer  Knockdown  Mcm10  Overexpression  Proliferation  Survival