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The Interaction of Calcium-Sensing Receptor with KIF11 Enhances Cisplatin Resistance in Lung Adenocarcinoma via BRCA1/cyclin B1 pathway Journal article
Wang, Fuhao, Fu, Xing, Chang, Ming, Wei, Tianzi, Lin, Risheng, Tong, Haibo, Zhang, Xiao, Yuan, Runzhu, Zhou, Zhiqing, Huang, Xin, Zhang, Wei, Su, Wenmei, Lu, Yi, Liang, Zhen, Zhang, Jian. The Interaction of Calcium-Sensing Receptor with KIF11 Enhances Cisplatin Resistance in Lung Adenocarcinoma via BRCA1/cyclin B1 pathway[J]. International Journal of Biological Sciences, 2024, 20(10), 3892-3910.
Authors:  Wang, Fuhao;  Fu, Xing;  Chang, Ming;  Wei, Tianzi;  Lin, Risheng; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:8.2/8.3 | Submit date：2024/10/10
Brca1  Casr  Chemoresistance  Cyclin B1  Kif11  Lung Adenocarcinoma  
CDK inhibitors from past to present: A new wave of cancer therapy Journal article
Muhammad Jameel Mughal, Kinjal Bhadresha, Hang Fai Kwok. CDK inhibitors from past to present: A new wave of cancer therapy[J]. Seminars in Cancer Biology, 2023, 88, 106-122.
Authors:  Muhammad Jameel Mughal;  Kinjal Bhadresha;  Hang Fai Kwok
Favorite | TC[WOS]:38 TC[Scopus]:38  IF:12.1/13.2 | Submit date：2023/02/08
Cancer Therapeutic Regimen  Cell Cycle  Combination Treatment  Cyclin-dependent Kinase Inhibitor  
Nannocystin ax, an eEF1A inhibitor, induces G1 cell cycle arrest and caspase-independent apoptosis through cyclin D1 downregulation in colon cancer in vivo Journal article
Hou, Ying, Liu, Rong, Xia, Mengwei, Sun, Chong, Zhong, Bingling, Yu, Jie, Ai, Nana, Lu, Jin Jian, Ge, Wei, Liu, Bo, Chen, Xiuping. Nannocystin ax, an eEF1A inhibitor, induces G1 cell cycle arrest and caspase-independent apoptosis through cyclin D1 downregulation in colon cancer in vivo[J]. Pharmacological Research, 2021, 173, 105870.
Authors:  Hou, Ying;  Liu, Rong;  Xia, Mengwei;  Sun, Chong;  Zhong, Bingling; et al.
Favorite | TC[WOS]:19 TC[Scopus]:18  IF:9.1/9.0 | Submit date：2021/12/08
Apoptosis  Cyclin D1  G1 Cell Cycle Arrest  Nannocystin Ax  
Discovery of a tetrahydroisoquinoline-based CDK9-cyclin T1 protein–protein interaction inhibitor as an anti-proliferative and anti-migration agent against triple-negative breast cancer cells Journal article
Shasha Cheng, Guan-Jun Yang, Wanhe Wang, Dik-Lung Ma, Chung-Hang Leung. Discovery of a tetrahydroisoquinoline-based CDK9-cyclin T1 protein–protein interaction inhibitor as an anti-proliferative and anti-migration agent against triple-negative breast cancer cells[J]. Genes & Diseases, 2021, 9(6), 1674-1688.
Authors:  Shasha Cheng;  Guan-Jun Yang;  Wanhe Wang;  Dik-Lung Ma;  Chung-Hang Leung
Favorite | TC[WOS]:23 TC[Scopus]:26  IF:6.9/7.2 | Submit date：2022/05/13
Cancer Stem Cells  Cdk9-cyclin T1  Epithelial Mesenchymal Transition  Protein–protein Interaction (Ppi)  Triple-negative Breast Cancer (Tnbc)  
Chaetominine induces cell cycle arrest in human leukemia K562 and colon cancer SW1116 cells Journal article
Yao, Jingyun, Xiao, Jianbo, Wei, Xing, Lu, Yanhua. Chaetominine induces cell cycle arrest in human leukemia K562 and colon cancer SW1116 cells[J]. ONCOLOGY LETTERS, 2018, 16(4), 4671-4678.
Authors:  Yao, Jingyun;  Xiao, Jianbo;  Wei, Xing;  Lu, Yanhua
Favorite | TC[WOS]:7 TC[Scopus]:8  IF:2.5/2.4 | Submit date：2018/10/30
Cell Cycle Arrest  Cyclin  Cyclin-dependent Kinase  Chaetominine  K562 Cells  Sw1116 Cells  
Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells Journal article
Zhang, Le-Le, Feng, Zhe-Ling, Su, Min-Xia, Jiang, Xiao-Ming, Chen, Xiuping, Wang, Yitao, Li, Ao, Lin, Li-Gen, Lu, Jin-Jian. Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells[J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 2018, 830, 17-25.
Authors:  Zhang, Le-Le;  Feng, Zhe-Ling;  Su, Min-Xia;  Jiang, Xiao-Ming;  Chen, Xiuping; et al.
View | Adobe PDF | Favorite | TC[WOS]:32 TC[Scopus]:32  IF:4.2/4.3 | Submit date：2018/10/30
Nagilactone e  Non-small Cell Lung Cancer  Cyclin B1  Cell Cycle  Apoptosis  
Up-regulation of CDK16 by multiple mechanisms in hepatocellular carcinoma promotes tumor progression Journal article
Wang, Yitao, Qin, Xian, Guo, Tao, Liu, Pengpeng, Wu, Ping, Liu, Zhisu. Up-regulation of CDK16 by multiple mechanisms in hepatocellular carcinoma promotes tumor progression[J]. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2017, 36.
Authors:  Wang, Yitao;  Qin, Xian;  Guo, Tao;  Liu, Pengpeng;  Wu, Ping; et al.
Favorite | TC[WOS]:19 TC[Scopus]:23 | Submit date：2018/11/01
Hepatocellular Carcinoma (Hcc)  Cyclin Dependent Kinase 16 (Cdk16)  Epithelial Mesenchymal Transition (Emt)  E2f1 Transcription Factor  Mir-125b-5p  
Histone H2A T120 Phosphorylation Promotes Oncogenic Transformation via Upregulation of Cyclin D1 Journal article
Aihara H., Nakagawa T., Mizusaki H., Yoneda M., Kato M., Doiguchi M., Imamura Y., Higashi M., Ikura T., Hayashi T., Kodama Y., Oki M., Nakayama T., Cheung E., Aburatani H., Takayama K.-I., Koseki H., Inoue S., Takeshima Y., Ito T.. Histone H2A T120 Phosphorylation Promotes Oncogenic Transformation via Upregulation of Cyclin D1[J]. Molecular Cell, 2016, 64(1), 176-188.
Authors:  Aihara H.;  Nakagawa T.;  Mizusaki H.;  Yoneda M.;  Kato M.; et al.
Favorite | TC[WOS]:45 TC[Scopus]:48 | Submit date：2018/12/17
Cyclin D1  H2a  Histone Modification  Nhk-1  Phosphorylation  Ubiquitylation  Vrk1  
Research progress on effects of indirubin and its structurally similar compounds on anticancer and neuroprotection Journal article
Wang,Ying, Sa,Fei, Chan,Yuet Wa, Lee,Ming Yuen. Research progress on effects of indirubin and its structurally similar compounds on anticancer and neuroprotection[J]. Chinese Traditional and Herbal Drugs, 2014, 45(16), 2404-2411.
Authors:  Wang,Ying;  Sa,Fei;  Chan,Yuet Wa;  Lee,Ming Yuen
Favorite | TC[Scopus]:3 | Submit date：2021/03/02
Anticancer  Cyclin-dependent Kinases  Glycogen Synthase Kinase-3  Indirubin  Neurodegeneration Disease  
The CDK1 inhibitor RO3306 improves the response of BRCA-proficient breast cancer cells to PARP inhibition Journal article
Xia Q., Cai Y., Peng R., Wu G., Shi Y., Jiang W.. The CDK1 inhibitor RO3306 improves the response of BRCA-proficient breast cancer cells to PARP inhibition[J]. International Journal of Oncology, 2014, 44(3), 735.
Authors:  Xia Q.;  Cai Y.;  Peng R.;  Wu G.;  Shi Y.; et al.
Favorite | TC[WOS]:46 TC[Scopus]:49 | Submit date：2018/10/30
Brca1  Breast Cancer  Cyclin-dependent Kinase 1  Poly (Adp-ribose) Polymerase Inhibitor