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Metabolomics-based discovery of XHP as a CYP3A4 inhibitor against pancreatic cancer Journal article
Yang,Yuting, Guo,Yanlei, Luo,Hua, Wang,Menglei, Chen,Fang, Cui,Huawei, Chen,Ping, Yin,Zhujun, Li,Li, Dai,Ying, Zeng,Jin, Zhao,Junning. Metabolomics-based discovery of XHP as a CYP3A4 inhibitor against pancreatic cancer[J]. Frontiers in Pharmacology, 2023, 14.
Authors:  Yang,Yuting;  Guo,Yanlei;  Luo,Hua;  Wang,Menglei;  Chen,Fang; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:4.4/5.0 | Submit date：2023/08/03
Cyp3a4  Pancreatic Cancer  Steroid Hormone Biosynthesis  Widely Targeted Metabolomics  Xihuang Pills  
Effects of Radix Astragali and Radix Rehmanniae, the components of an anti-diabetic foot ulcer herbal formula, on metabolism of model CYP1A2, CYP2C9, CYP2D6, CYP2E1 and CYP3A4 probe substrates in pooled human liver microsomes and specific CYP isoforms Journal article
Or P.M.Y., Lam F.F.Y., Kwan Y.W., Cho C.H., Lau C.P., Yu H., Lin G., Lau C.B.S., Fung K.P., Leung P.C., Yeung J.H.K.. Effects of Radix Astragali and Radix Rehmanniae, the components of an anti-diabetic foot ulcer herbal formula, on metabolism of model CYP1A2, CYP2C9, CYP2D6, CYP2E1 and CYP3A4 probe substrates in pooled human liver microsomes and specific CYP isoforms[J]. Phytomedicine, 2012, 19(6), 535-544.
Authors:  Or P.M.Y.;  Lam F.F.Y.;  Kwan Y.W.;  Cho C.H.;  Lau C.P.; et al.
Favorite | TC[WOS]:35 TC[Scopus]:38 | Submit date：2019/01/17
Cyp1a2  Cyp2c9  Cyp2d6  Cyp2e1  Cyp3a4  Human Liver Microsomes  Radix Astragali  Radix Rehmanniae  
Regulation of human pregnane X receptor and its target gene cytochrome P450 3A4 by Chinese herbal compounds and a molecular docking study Journal article
Liu, YH (Liu, Ya-He), Mo, SL (Mo, Sui-Lin), Bi, HC (Bi, Hui-Chang), Hu, BF (Hu, Bing-Fang), Li, CG (Li, Chun Guang), Wang, YT (Wang, Yi-Tao), Huang, L (Huang, Ling), Huang, M (Huang, Min), Duan, W (Duan, Wei), Liu, JP (Liu, Jun-Ping), Wei, MQ (Wei, Ming Qian), Zhou, SF (Zhou, Shu-Feng). Regulation of human pregnane X receptor and its target gene cytochrome P450 3A4 by Chinese herbal compounds and a molecular docking study[J]. XENOBIOTICA, 2011, 41(4), 259-280.
Authors:  Liu, YH (Liu, Ya-He);  Mo, SL (Mo, Sui-Lin);  Bi, HC (Bi, Hui-Chang);  Hu, BF (Hu, Bing-Fang);  Li, CG (Li, Chun Guang); et al.
Favorite | TC[WOS]:46 TC[Scopus]:48  IF:1.3/1.4 | Submit date：2018/11/01
Constitutive Androstane Receptor  Primary Human Hepatocytes  Corepressor Silencing-mediator  Hepatoma-cell Lines  Human Cyp3a4 Gene  Nuclear Receptor  Drug-metabolism  Transcriptional Activation  Xenobiotic Receptor  Interindividual Variability