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Upgrade of chrysomycin A as a novel topoisomerase II inhibitor to curb KRAS-mutant lung adenocarcinoma progression Journal article
Zhang JunMin, Liu Pei, Chen JianWei, Yao DaHong, Liu Qing, Zhang JuanHong, Zhang Hua Wei, Leung Elaine Lai Han, Yao XiaoJun, Liu Liang. Upgrade of chrysomycin A as a novel topoisomerase II inhibitor to curb KRAS-mutant lung adenocarcinoma progression[J]. Pharmacological Research, 2023, 187.
Authors:  Zhang JunMin;  Liu Pei;  Chen JianWei;  Yao DaHong;  Liu Qing; et al.
Favorite | TC[WOS]:5 TC[Scopus]:5  IF:9.1/9.0 | Submit date：2023/02/08
Apoptosis  Chrysomycin a  Dna Damage  Reactive Oxygen Species  Topoisomerase Ii Activity  
Phytochemical naphtho[1,2-b] furan-4,5‑dione induced topoisomerase II-mediated DNA damage response in human non-small-cell lung cancer Journal article
Chien , C. M., Yang, J. C., Wu, P. H., Wu, C. Y., Chen, G. Y., Wu, Y. C. , Chou, C. K., Tseng, C. H., Chen, Y. L., Wang, L. F., Chiu, C. C.. Phytochemical naphtho[1,2-b] furan-4,5‑dione induced topoisomerase II-mediated DNA damage response in human non-small-cell lung cancer[J]. Phytomedicine, 2019, 109-119.
Authors:  Chien , C. M.;  Yang, J. C.;  Wu, P. H.;  Wu, C. Y.;  Chen, G. Y.; et al.
Favorite |  | Submit date：2022/09/21
Apoptosis  DNA damage  NF-Κb  Naphthoquinone  Non-small cell lung cancer  Topoisomerase II activity.  
Investigational hypoxia-activated prodrugs: Making sense of future development Journal article
Min Xia Su, Le Le Zhang, Zhang Jian Huang, Jia Jie Shi, Jin Jian Lu. Investigational hypoxia-activated prodrugs: Making sense of future development[J]. CURRENT DRUG TARGETS, 2019, 20(6), 668-678.
Authors:  Min Xia Su;  Le Le Zhang;  Zhang Jian Huang;  Jia Jie Shi;  Jin Jian Lu
Favorite | TC[WOS]:9 TC[Scopus]:11  IF:3.0/3.3 | Submit date：2021/03/02
Dna Alkylating Agents  Hypoxia-activated Prodrug  Patient Selection  Reductase Activity  Targeted Drugs  Topoisomerase Ii Inhibitors  
Effect of active compounds isolated from Pteris semipinnata L on DNA topoisomerases and tyrosine protein kinase and expression of c-myc in lung adenocarcinoma cells Journal article
Li J.-H., Liang N.-C., Mo L.-E., Zhang X., He C.-W.. Effect of active compounds isolated from Pteris semipinnata L on DNA topoisomerases and tyrosine protein kinase and expression of c-myc in lung adenocarcinoma cells[J]. Chinese Journal of Cancer Research, 2001, 13(2), 105-109.
Authors:  Li J.-H.;  Liang N.-C.;  Mo L.-E.;  Zhang X.;  He C.-W.
Favorite | TC[Scopus]:4 | Submit date：2018/12/28
C-myc  Dna Topoisomerase  Pteris Semipinnata L.  Tyrosine Protein Kinase  
Effects of antitumor compounds isolated from Pteris semipinnata L on DNA topoisomerases and cell cycle of HL-60 cells Journal article
Li J.-H., He C.-W., Liang N.-C., Mo L.-E., Zhang X.. Effects of antitumor compounds isolated from Pteris semipinnata L on DNA topoisomerases and cell cycle of HL-60 cells[J]. Acta Pharmacologica Sinica, 1999, 20(6), 541-545.
Authors:  Li J.-H.;  He C.-W.;  Liang N.-C.;  Mo L.-E.;  Zhang X.
Favorite |  | Submit date：2018/12/28
Antineoplastic agents  Cell cycle  Diterpenes  DNA topoisomerase  Drag synergism  Genistein  HL-60 cells  Pteris semipinnata L