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Activation of the PERK/eIF2α axis is a pivotal prerequisite of taxanes to cancer cell apoptosis and renders synergism to overcome paclitaxel resistance in breast cancer cells Journal article
Cai, Wanhua, Rong, Dade, Ding, Jiayu, Zhang, Xiaomei, Wang, Yuwei, Fang, Ying, Xiao, Jing, Yang, Shulan, Wang, Haihe. Activation of the PERK/eIF2α axis is a pivotal prerequisite of taxanes to cancer cell apoptosis and renders synergism to overcome paclitaxel resistance in breast cancer cells[J]. Cancer Cell International, 2024, 24(1), 249.
Authors:  Cai, Wanhua;  Rong, Dade;  Ding, Jiayu;  Zhang, Xiaomei;  Wang, Yuwei; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:5.3/5.0 | Submit date：2024/08/05
Breast Cancer  Er Stress  Perk/eif2α  Taxane  Tumor Drug Resistance  
Tanshinone IIA induces ER stress and JNK activation to inhibit tumor growth and enhance anti-PD-1 immunotherapy in non-small cell lung cancer Journal article
Zhang YiZhong, Lai HuanLing, Huang Chen, Jiang ZeBo, Yan HaoXin, Wang XuanRun, Xie Chun, Huang JuMin, Ren WenKang, Li JiaXin, Zhai ZhiRan, Yao XiaoJun, Wu QiBiao, Leung Elaine Lai Han. Tanshinone IIA induces ER stress and JNK activation to inhibit tumor growth and enhance anti-PD-1 immunotherapy in non-small cell lung cancer[J]. Phytomedicine, 2024, 128, 155431.
Authors:  Zhang YiZhong;  Lai HuanLing;  Huang Chen;  Jiang ZeBo;  Yan HaoXin; et al.
Favorite | TC[WOS]:0 TC[Scopus]:1  IF:6.7/6.2 | Submit date：2024/05/16
Er Stress  Jnk  Nfat2  Nsclc  Pd-l1  Tanshinone Iia  
Ginsenoside Rk1 Ameliorates ER Stress-Induced Apoptosis through Directly Activating IGF-1R in Mouse Pancreatic β -Cells and Diabetic Pancreas Journal article
Vong, Chi Teng, Tan, Dechao, Liao, Fengyun, Chen, Zhejie, Chen, Zhangmei, Tseng, Hisa Hui Ling, Cheang, Wai San, Wang, Shengpeng, Wang, Yitao. Ginsenoside Rk1 Ameliorates ER Stress-Induced Apoptosis through Directly Activating IGF-1R in Mouse Pancreatic β -Cells and Diabetic Pancreas[J]. American Journal of Chinese Medicine, 2024, 52(4), 1195-1211.
Authors:  Vong, Chi Teng;  Tan, Dechao;  Liao, Fengyun;  Chen, Zhejie;  Chen, Zhangmei; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:4.8/5.0 | Submit date：2024/07/04
Diabetes  Diabetic Pancreas  Er Stress  Ginsenoside Rk1  Insulin-like Growth Factor 1 Receptor  β -cell Apoptosis  
Paraptosis: a non-classical paradigm of cell death for cancer therapy Journal article
Xu, Chun cao, Lin, Yi fan, Huang, Mu yang, Zhang, Xiao lei, Wang, Pei, Huang, Ming qing, Lu, Jin jian. Paraptosis: a non-classical paradigm of cell death for cancer therapy[J]. Acta Pharmacologica Sinica, 2024, 45(2), 223-237.
Authors:  Xu, Chun cao;  Lin, Yi fan;  Huang, Mu yang;  Zhang, Xiao lei;  Wang, Pei; et al.
Favorite | TC[WOS]:20 TC[Scopus]:17  IF:6.9/7.6 | Submit date：2024/05/16
cancer therapy  endoplasmic reticulum  ER stress  mitochondria  paraptosis  
Paraptosis: a non-classical paradigm of cell death for cancer therapy Review article
2024
Authors:  Xu, Chun cao;  Lin, Yi fan;  Huang, Mu yang;  Zhang, Xiao lei;  Wang, Pei; et al.
Favorite | TC[WOS]:20 TC[Scopus]:17  IF:6.9/7.6 | Submit date：2024/02/22
Cancer Therapy  Endoplasmic Reticulum  Er Stress  Mitochondria  Paraptosis  
Strategies targeting endoplasmic reticulum stress to improve Parkinson's disease Journal article
Wang, Danni, Qu, Shuhui, Zhang, Zaijun, Tan, Liang, Chen, Xiuping, Zhong, Hai-Jing, Chong, Cheong Meng. Strategies targeting endoplasmic reticulum stress to improve Parkinson's disease[J]. Frontiers in Pharmacology, 2023, 14, 1288894.
Authors:  Wang, Danni;  Qu, Shuhui;  Zhang, Zaijun;  Tan, Liang;  Chen, Xiuping; et al.
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:4.4/5.0 | Submit date：2023/12/11
Er Stress  Parkinson’s Disease  Dopaminergic Neurons  Protein Homeostasis  Unfolded Protein Response  
ER translocon inhibitor ipomoeassin F inhibits triple-negative breast cancer growth via blocking ER molecular chaperones Journal article
Shishi Tao, Eun Ju Yang, Guanghui Zong, Pui Kei Mou, Guowen Ren, Yue Pu, Liang Chen, Ho Jeong Kwon, Jianhong Zhou, Zhijian Hu, Arman Khosravi, Qingyang Zhang, Yuchun Du, Wei Q. Shi, Joong Sup Shim. ER translocon inhibitor ipomoeassin F inhibits triple-negative breast cancer growth via blocking ER molecular chaperones[J]. Int J Biol Sci, 2023, 19(13), 4020-4035.
Authors:  Shishi Tao;  Eun Ju Yang;  Guanghui Zong;  Pui Kei Mou;  Guowen Ren; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:8.2/8.3 | Submit date：2023/08/30
Ipomoeassin f  Er Stress  Er Translocon  Tnbc  Pdia6  Pdia4  
TRIM59 guards ER proteostasis and prevents Bortezomib-mediated colorectal cancer (CRC) cells’ killing Journal article
Xuejia Feng, Gui Yang, Litian Zhang, Shishi Tao, Joong Sup SHIM, Liang Chen, Qingxia Wu. TRIM59 guards ER proteostasis and prevents Bortezomib-mediated colorectal cancer (CRC) cells’ killing[J]. INVESTIGATIONAL NEW DRUGS, 2022, 40(6), 1244-1253.
Authors:  Xuejia Feng;  Gui Yang;  Litian Zhang;  Shishi Tao;  Joong Sup SHIM; et al.
Favorite | TC[WOS]:3 TC[Scopus]:3  IF:3.0/2.9 | Submit date：2023/01/30
Trim59  Er-stress  Unfolded Protein Response  Er-associated Degradation  Bortezomib  Colorectal Cancer  
TFEB, a master regulator of autophagy and biogenesis, unexpectedly promotes apoptosis in response to the cyclopentenone prostaglandin 15d-PGJ2 Journal article
Yang, Chuan bin, Liu, Jia, Tong, Benjamin Chun Kit, Wang, Zi ying, Zhu, Zhou, Su, Cheng fu, Sreenivasmurthy, Sravan Gopalkrishnashetty, Wu, Jia xi, Iyaswamy, Ashok, Krishnamoorthi, Senthilkumar, Huang, Shi ying, Cheung, King ho, Song, Ju xian, Tan, Jie qiong, Lu, Jia hong, Li, Min. TFEB, a master regulator of autophagy and biogenesis, unexpectedly promotes apoptosis in response to the cyclopentenone prostaglandin 15d-PGJ2[J]. Acta Pharmacologica Sinica, 2022, 43(5), 1251-1263.
Authors:  Yang, Chuan bin;  Liu, Jia;  Tong, Benjamin Chun Kit;  Wang, Zi ying;  Zhu, Zhou; et al.
Favorite | TC[WOS]:18 TC[Scopus]:19  IF:6.9/7.6 | Submit date：2022/05/13
15-deoxy-∆-12,14-prostaglandin J2 (15d-pgJ2)  Apoptosis  Atf4  Autophagy And Lysosome Biogenesis  Er Stress  Transcriptional Factor Eb (tfEb)  
Neferine alleviates memory and cognitive dysfunction in diabetic mice through modulation of the NLRP3 inflammasome pathway and alleviation of endoplasmic-reticulum stress Journal article
Wu, Xiao Li, Deng, Min Zhen, Gao, Zhi Jie, Dang, Yuan Ye, Li, Yu Cui, Li, Chu Wen. Neferine alleviates memory and cognitive dysfunction in diabetic mice through modulation of the NLRP3 inflammasome pathway and alleviation of endoplasmic-reticulum stress[J]. International Immunopharmacology, 2020, 84, 106559.
Authors:  Wu, Xiao Li;  Deng, Min Zhen;  Gao, Zhi Jie;  Dang, Yuan Ye;  Li, Yu Cui; et al.
Favorite | TC[WOS]:36 TC[Scopus]:39  IF:4.8/5.0 | Submit date：2021/12/06
Neferine  Diabetes Mellitus  Cognitive And Memory Dysfunction  Nlrp3 Inflammasome  Er Stress