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The enhancing effects of selenomethionine on harmine in attenuating pathological cardiac hypertrophy via glycolysis metabolism Journal article
Chen, Qi, Wang, Wen Yan, Xu, Qing Yang, Dai, Yan Fa, Zhu, Xing Yu, Chen, Zhao Yang, Sun, Ning, Leung, Chung Hang, Gao, Fei, Wu, Ke Jia. The enhancing effects of selenomethionine on harmine in attenuating pathological cardiac hypertrophy via glycolysis metabolism[J]. Journal of Cellular and Molecular Medicine, 2024, 28(19), e70124.
Authors:  Chen, Qi;  Wang, Wen Yan;  Xu, Qing Yang;  Dai, Yan Fa;  Zhu, Xing Yu; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:4.3/5.0 | Submit date：2024/10/10
Cardiac Hypertrophy  Combination Therapy  Glycolysis Metabolism  Harmine  Selenomethionine  
Dichloroacetophenone derivatives as pyruvate dehydrogenase kinase inhibitor in non-small cell lung cancer models Presentation
会议地点: University Rectorate, Belgrade, Serbia, 会议日期: 4-6 September, 2023, 报告日期: 2023-09-05
Authors:  TAM KIN YIP
Favorite |  | Submit date：2024/08/30
Cancer Metabolism  Aerobic Glycolysis  Pyruvate Dehydrogenase Kinase  
ALDH1A3 Coordinates Metabolism with Gene Regulation in Pulmonary Arterial Hypertension Journal article
Li, Dan, Shao, Ning Yi, Moonen, Jan Renier, Zhao, Zhixin, Shi, Minyi, Otsuki, Shoichiro, Wang, Lingli, Nguyen, Tiffany, Yan, Elaine, Marciano, David P., Contrepois, Kévin, Li, Caiyun G., Wu, Joseph C., Snyder, Michael P., Rabinovitch, Marlene. ALDH1A3 Coordinates Metabolism with Gene Regulation in Pulmonary Arterial Hypertension[J]. Circulation, 2021, 143(21), 2074-2090.
Authors:  Li, Dan;  Shao, Ning Yi;  Moonen, Jan Renier;  Zhao, Zhixin;  Shi, Minyi; et al.
Favorite | TC[WOS]:46 TC[Scopus]:48  IF:35.5/32.7 | Submit date：2022/05/13
Cell Cycle  Glycolysis  Metabolism  Myocytes, Smooth Muscle  Proliferation  Pulmonary Arterial Hypertension  
Recent developments of human monocarboxylate transporter (hMCT) inhibitors as anticancer agents Journal article
Wu Pahau, Zhou Yan, Guo Yizhen, Shaolin Zhang, TAM KIN YIP. Recent developments of human monocarboxylate transporter (hMCT) inhibitors as anticancer agents[J]. Drug Discovery Today, 2021, 26(3), 836-844.
Authors:  Wu Pahau;  Zhou Yan;  Guo Yizhen;  Shaolin Zhang;  TAM KIN YIP
Adobe PDF | Favorite | TC[WOS]:14 TC[Scopus]:13  IF:6.5/7.3 | Submit date：2024/08/29
Antineoplastic Agents  Drug Design  Drug Development  Glucose/metabolism  Glycolysis  Humans Monocarboxylic Acid Transporters  
LC/MS/MS method revealed that lung cancer cells exhibited distinct metabolite profiles upon the treatment with different anticancer pyruvate dehydrogenase kinases (PDKs) inhibitors Presentation
会议地点: Hotel Park, Split, Croatia, 会议日期: 9-11 September 2019, 报告日期: 2019-09-09
Authors:  TAM KIN YIP
Favorite |  | Submit date：2024/08/30
Aerobic Glycolysis  Lc-ms/ms  Pyruvate Dehydrogenase Kinases  Cancer Metabolism  
Elevated Exogenous Pyruvate Potentiates Mesodermal Differentiation through Metabolic Modulation and AMPK/mTOR Pathway in Human Embryonic Stem Cells Journal article
Chengcheng Song, Faxiang Xu, Zhili Ren, Yumeng Zhang, Ya Meng, Yiqi Yang, Shreyas Lingadahalli, Edwin Cheung, Gang Li, Weiwei Liu, Jianbo Wan, Yang Zhao, Guokai Chen. Elevated Exogenous Pyruvate Potentiates Mesodermal Differentiation through Metabolic Modulation and AMPK/mTOR Pathway in Human Embryonic Stem Cells[J]. STEM CELL REPORTS, 2019, 13(2), 338-351.
Authors:  Chengcheng Song;  Faxiang Xu;  Zhili Ren;  Yumeng Zhang;  Ya Meng; et al.
Favorite | TC[WOS]:29 TC[Scopus]:34  IF:5.9/5.9 | Submit date：2020/04/22
Hescs  Pyruvate  Bmp4  Glycolysis  Tca Cycle  Ampk  Wnt  Metabolism  Mesoderm  Differentiation  
The epigenetically downregulated factor CYGB suppresses breast cancer through inhibition of glucose metabolism Journal article
Feng, Yixiao, Wu, Mingjun, Li, Shuman, He, Xiaoqian, Tang, Jun, Peng, Weiyan, Zeng, Beilei, Deng, Chuxia, Ren, Guosheng, Xiang, Tingxiu. The epigenetically downregulated factor CYGB suppresses breast cancer through inhibition of glucose metabolism[J]. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2018, 37.
Authors:  Feng, Yixiao;  Wu, Mingjun;  Li, Shuman;  He, Xiaoqian;  Tang, Jun; et al.
Favorite | TC[WOS]:16 TC[Scopus]:21 | Submit date：2019/01/17
Cygb  Glut1  Hxk2  P53  Breast Cancer  Metabolism  Glycolysis  
Liquid Chromatography-Tandem Mass Spectrometry Method Revealed that Lung Cancer Cells Exhibited Distinct Metabolite Profiles upon the Treatment with Different Pyruvate Dehydrogenase Kinase Inhibitors Journal article
Zhang, Wen, Hu, Xiaohui, Zhou, Wei, Tam, Kin Yip. Liquid Chromatography-Tandem Mass Spectrometry Method Revealed that Lung Cancer Cells Exhibited Distinct Metabolite Profiles upon the Treatment with Different Pyruvate Dehydrogenase Kinase Inhibitors[J]. JOURNAL OF PROTEOME RESEARCH, 2018, 17(9), 3012-3021.
Authors:  Zhang, Wen;  Hu, Xiaohui;  Zhou, Wei;  Tam, Kin Yip
Favorite | TC[WOS]:18 TC[Scopus]:18  IF:3.8/4.1 | Submit date：2018/10/30
Aerobic Glycolysis  Azd7545  Dichloroacetate  Lc-ms/ms  Pyruvate Dehydrogenase Kinases  Cancer Metabolism  
Liquid Chromatography–Tandem Mass Spectrometry Method Revealed that Lung Cancer Cells Exhibited Distinct Metabolite Profiles upon the Treatment with Different Pyruvate Dehydrogenase Kinase Inhibitors Journal article
Zhang, W., Hu, X., Zhou, W., Tam, K. Y.. Liquid Chromatography–Tandem Mass Spectrometry Method Revealed that Lung Cancer Cells Exhibited Distinct Metabolite Profiles upon the Treatment with Different Pyruvate Dehydrogenase Kinase Inhibitors[J]. Journal of Proteome Research, 2018, 1-10.
Authors:  Zhang, W.;  Hu, X.;  Zhou, W.;  Tam, K. Y.
Favorite | TC[WOS]:18 TC[Scopus]:18  IF:3.8/4.1 | Submit date：2022/07/28
Aerobic Glycolysis  Azd7545  Cancer Metabolism  Dichloroacetate  Lc−ms/ms  Pyruvate Dehydrogenase Kinases  
Targeting tumor metabolism for cancer treatment: Is pyruvate dehydrogenase kinases (PDKs) a viable anticancer target? Journal article
Wen Zhang, Shao-Lin Zhang, Xiaohui Hu, Kin Yip Tam. Targeting tumor metabolism for cancer treatment: Is pyruvate dehydrogenase kinases (PDKs) a viable anticancer target?[J]. International Journal of Biological Sciences, 2015, 11(12), 1390-1400.
Authors:  Wen Zhang;  Shao-Lin Zhang;  Xiaohui Hu;  Kin Yip Tam
Favorite | TC[WOS]:118 TC[Scopus]:125  IF:8.2/8.3 | Submit date：2019/01/07
Aerobic Glycolysis  Pyruvate Dehydrogenase Kinases  Tumor Metabolism  Pyruvate Dehydrogenase Complex