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Canagliflozin mediates mitophagy through the AMPK/PINK1/PARKIN pathway to alleviate isoprenaline-induced cardiac remodelling Journal article
Gong, Shaolin, Sui, Yuan, Xiao, Mengxuan, Fu, Daoyao, Xiong, Zhiping, Zhang, Liuping, Tian, Qingshan, Fu, Yongnan, Xiong, Wenjun. Canagliflozin mediates mitophagy through the AMPK/PINK1/PARKIN pathway to alleviate isoprenaline-induced cardiac remodelling[J]. Journal of Cardiovascular Pharmacology, 2024, 84(5), 496-505.
Authors:  Gong, Shaolin;  Sui, Yuan;  Xiao, Mengxuan;  Fu, Daoyao;  Xiong, Zhiping; et al.
Favorite | TC[WOS]:1 TC[Scopus]:0  IF:2.6/2.5 | Submit date：2024/09/03
Canagliflozin  Cardiac Remodeling  Cardioprotective  Mitophagy  Sglt-2 Inhibitor  
Glucuronidation Homeostasis in Colorectal Cancer: New Mechanistic Insights into Carcinogenesis and Precision Medicine Presentation
会议地点: Macao, 会议日期: Aug 24-26, 2024, 报告日期: 2024-08-01
Authors:  YAN RU
Adobe PDF | Favorite |  | Submit date：2024/08/31
Glucuronidation Homeostasis  Colorectal Cancer  Precision Medicine  Gut Microbial Β-glucuronidases  Gus Inhibitor  
Exploring the roles of excess amino acids, creatine, creatinine, and glucose in the formation of heterocyclic aromatic amines by UPLC-MS/MS Journal article
Zhang, Haolin, Lv, Xiaomei, Su, Weiming, Chen, Bing Huei, Lai, Yu Wen, Xie, Ruiwei, Lin, Qiuyi, Chen, Lei, Cao, Hui. Exploring the roles of excess amino acids, creatine, creatinine, and glucose in the formation of heterocyclic aromatic amines by UPLC-MS/MS[J]. Food Chemistry, 2024, 446, 138760.
Authors:  Zhang, Haolin;  Lv, Xiaomei;  Su, Weiming;  Chen, Bing Huei;  Lai, Yu Wen; et al.
Favorite | TC[WOS]:3 TC[Scopus]:3  IF:8.5/8.2 | Submit date：2024/05/16
Carcinogen  Excess Addition  Formation Mechanism  Inhibitor  Lc-ms  Precursor  
Pan-cancer analysis of CDKN2A alterations identifies a subset of gastric cancer with a cold tumor immune microenvironment Journal article
Deng, Chao, Li, Zi Xi, Xie, Chen Jun, Zhang, Qing Lin, Hu, Ben Shun, Wang, Mei Dan, Mei, Jie, Yang, Chen, Zhong, Zhangfeng, Wang, Ke Wei. Pan-cancer analysis of CDKN2A alterations identifies a subset of gastric cancer with a cold tumor immune microenvironment[J]. Human Genomics, 2024, 18(1), 55.
Authors:  Deng, Chao;  Li, Zi Xi;  Xie, Chen Jun;  Zhang, Qing Lin;  Hu, Ben Shun; et al.
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:3.8/4.0 | Submit date：2024/07/04
Cdkn2a  Immune Checkpoint Inhibitor  Immunotherapy  Pan-cancer  
Real-world treatment patterns and outcomes for patients with advanced hepatocellular carcinoma initially treated with PD-1 inhibitors Journal article
Zou, Huimin, Ge, Ying, Chen, Wenge, Yao, Dongning, Oi Lam Ung, Carolina, Lai, Yunfeng, Hu, Hao. Real-world treatment patterns and outcomes for patients with advanced hepatocellular carcinoma initially treated with PD-1 inhibitors[J]. International Immunopharmacology, 2024, 132, 111947.
Authors:  Zou, Huimin;  Ge, Ying;  Chen, Wenge;  Yao, Dongning;  Oi Lam Ung, Carolina; et al.
Favorite | TC[WOS]:0 TC[Scopus]:1  IF:4.8/5.0 | Submit date：2024/05/16
Camrelizumab  China  Hepatocellular Carcinoma  Programmed Cell Death Protein-1 Inhibitor  Tislelizumab  
Ferroptosis inhibitor alleviates sorafenib-induced cardiotoxicity by attenuating KLF11-mediated FSP1-dependent ferroptosis Journal article
Li, Yilan, Yan, Jingru, Sun, Heng, Liang, Yating, Zhao, Qianqian, Yu, Shan, Zhang, Yao. Ferroptosis inhibitor alleviates sorafenib-induced cardiotoxicity by attenuating KLF11-mediated FSP1-dependent ferroptosis[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2024, 20(7), 2622-2639.
Authors:  Li, Yilan;  Yan, Jingru;  Sun, Heng;  Liang, Yating;  Zhao, Qianqian; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:8.2/8.3 | Submit date：2024/06/05
Cardiotoxicity  Ferroptosis Inhibitor  Fsp1  Gpx4  Klf11  Sorafenib  
Blocking Ubiquitin-Specific Protease 7 Induces Ferroptosis in Gastric Cancer via Targeting Stearoyl-CoA Desaturase Journal article
Guan, Xiaoqing, Wang, Yichao, Yu, Wenkai, Wei, Yong, Lu, Yang, Dai, Enyu, Dong, Xiaowu, Zhao, Bing, Hu, Can, Yuan, Li, Luan, Xin, Miao, Kai, Chen, Bonan, Cheng, Xiang Dong, Zhang, Weidong, Qin, Jiang Jiang. Blocking Ubiquitin-Specific Protease 7 Induces Ferroptosis in Gastric Cancer via Targeting Stearoyl-CoA Desaturase[J]. Advanced Science, 2024, 11(18), 2307899.
Authors:  Guan, Xiaoqing;  Wang, Yichao;  Yu, Wenkai;  Wei, Yong;  Lu, Yang; et al.
Favorite | TC[WOS]:4 TC[Scopus]:4  IF:14.3/16.3 | Submit date：2024/05/16
Ferroptosis  Gastric Cancer  Scd  Ubiquitination  Usp7  Usp7 Inhibitor  
Covalent inhibition of epidermal growth factor receptor using a long-lived iridium(III)-afatinib probe Journal article
Nao, Sang Cuo, Kong, Lingtan, Chan, Daniel Shiu Hin, Liu, Jianhua, Huang, Le Sheng, Wu, Lei, Wu, Jia, Wong, Chun Yuen, Wang, Wanhe, Leung, Chung Hang. Covalent inhibition of epidermal growth factor receptor using a long-lived iridium(III)-afatinib probe[J]. International Journal of Biological Macromolecules, 2024, 259, 129211.
Authors:  Nao, Sang Cuo;  Kong, Lingtan;  Chan, Daniel Shiu Hin;  Liu, Jianhua;  Huang, Le Sheng; et al.
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:7.7/7.7 | Submit date：2024/02/22
Afatinib Conjugate  Covalent Inhibitor  Egfr  Iridium Complex  Multifunctional Probe  
Discovery of a potent and selective covalent threonine tyrosine kinase (TTK) inhibitor Journal article
Sun, Yaoliang, Chen, Zhiwen, Liu, Guobin, Chen, Xiaoai, Shi, Zihan, Feng, Huixu, Yu, Lei, Li, Guodong, Ding, Ke, Huang, He, Zhang, Zhang, Xu, Shilin. Discovery of a potent and selective covalent threonine tyrosine kinase (TTK) inhibitor[J]. Bioorganic Chemistry, 2023, 143, 107053.
Authors:  Sun, Yaoliang;  Chen, Zhiwen;  Liu, Guobin;  Chen, Xiaoai;  Shi, Zihan; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:4.5/4.7 | Submit date：2024/02/22
Cancer  Covalent  Inhibitor  Threonine Tyrosine Kinase (Ttk)  
Targeting STAT3-VISTA axis to suppress tumor aggression and burden in acute myeloid leukemia Journal article
Mo, Jianshan, Deng, Lin, Peng, Keren, Ouyang, Shumin, Ding, Wen, Lou, Linlin, Lin, Ziyou, Zhu, Jianzheng, Li, Jingwei, Zhang, Qiyi, Wang, Pengyan, Wen, Yuanzhen, Chen, Xiaobing, Yue, Peibin, Lu, Jin Jian, Zhu, Kai, Zheng, Yongjiang, Wang, Yuanxiang, Zhang, Xiaolei. Targeting STAT3-VISTA axis to suppress tumor aggression and burden in acute myeloid leukemia[J]. Journal of Hematology & Oncology, 2023, 16(1), 15.
Authors:  Mo, Jianshan;  Deng, Lin;  Peng, Keren;  Ouyang, Shumin;  Ding, Wen; et al.
Favorite | TC[WOS]:15 TC[Scopus]:14  IF:29.5/26.9 | Submit date：2023/03/06
Aml  Immunotherapy  Stat3 Inhibitor  Vista