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Tanshinone IIA induces ER stress and JNK activation to inhibit tumor growth and enhance anti-PD-1 immunotherapy in non-small cell lung cancer Journal article
Zhang YiZhong, Lai HuanLing, Huang Chen, Jiang ZeBo, Yan HaoXin, Wang XuanRun, Xie Chun, Huang JuMin, Ren WenKang, Li JiaXin, Zhai ZhiRan, Yao XiaoJun, Wu QiBiao, Leung Elaine Lai Han. Tanshinone IIA induces ER stress and JNK activation to inhibit tumor growth and enhance anti-PD-1 immunotherapy in non-small cell lung cancer[J]. Phytomedicine, 2024, 128, 155431.
Authors:  Zhang YiZhong;  Lai HuanLing;  Huang Chen;  Jiang ZeBo;  Yan HaoXin; et al.
Favorite | TC[WOS]:0 TC[Scopus]:1  IF:6.7/6.2 | Submit date：2024/05/16
Er Stress  Jnk  Nfat2  Nsclc  Pd-l1  Tanshinone Iia  
Unveil the mechanism for EHMT – A novel triterpenoid inhibits proliferation and induces apoptosis in colon cancer through ROS-mediated JNK signaling pathway Journal article
Wu, Qiushuang, Song, Min, Luo, Siyuan, Guo, Libin, Zhang, Qingwen, Kwok, Hang Fai. Unveil the mechanism for EHMT – A novel triterpenoid inhibits proliferation and induces apoptosis in colon cancer through ROS-mediated JNK signaling pathway[J]. Biomedicine and Pharmacotherapy, 2024, 174, 116469.
Authors:  Wu, Qiushuang;  Song, Min;  Luo, Siyuan;  Guo, Libin;  Zhang, Qingwen; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:6.9/6.8 | Submit date：2024/05/16
Apoptosis  Colon Cancer  Jnk Pathways  Natural Products  Ros  Triterpenoid  
Glycyrrhetinic acid suppresses breast cancer metastasis by inhibiting M2-like macrophage polarization via activating JNK1/2 signaling Journal article
Yanfen Cheng, Xuemei Zhong, Xin Nie, Huan Gu, Xiaoping Wu, Renkai Li, Yihan Wu, Kongpeng Lv, George Pak-Heng Leung, Chaomei Fu, Simon Ming-Yuen Lee, Jinming Zhang, Jingjing Li. Glycyrrhetinic acid suppresses breast cancer metastasis by inhibiting M2-like macrophage polarization via activating JNK1/2 signaling[J]. Phytomedicine, 2023, 114, 154757.
Authors:  Yanfen Cheng;  Xuemei Zhong;  Xin Nie;  Huan Gu;  Xiaoping Wu; et al.
Favorite | TC[WOS]:21 TC[Scopus]:19  IF:6.7/6.2 | Submit date：2023/07/27
Angiogenesis  Breast Cancer Metastasis  Glycyrrhetinic Acid  Jnk1/2 Pathway  Tumor-associated Macrophages  
Network pharmacology-based investigation and experimental validation of the mechanism of scutellarin in the treatment of acute myeloid leukemia Journal article
Huang, Zhe, Yang, Yan, Fan, Xianming, Ma, Wenzhe. Network pharmacology-based investigation and experimental validation of the mechanism of scutellarin in the treatment of acute myeloid leukemia[J]. Frontiers in Pharmacology, 2022, 13.
Authors:  Huang, Zhe;  Yang, Yan;  Fan, Xianming;  Ma, Wenzhe
Favorite | TC[WOS]:5 TC[Scopus]:5  IF:4.4/5.0 | Submit date：2023/01/30
Aml  Apoptosis  Jnk/caspase-3 Signal Pathway  Network Pharmacology  Scutellarin  
Psoralidin, a natural compound from Psoralea corylifolia, induces oxidative damage mediated apoptosis in colon cancer cells Journal article
Sun, Chong, Zhao, Lin, Wang, Xianzhe, Hou, Ying, Guo, Xiuli, Lu, Jin Jian, Chen, Xiuping. Psoralidin, a natural compound from Psoralea corylifolia, induces oxidative damage mediated apoptosis in colon cancer cells[J]. Journal of Biochemical and Molecular Toxicology, 2022, 36(7), e23051.
Authors:  Sun, Chong;  Zhao, Lin;  Wang, Xianzhe;  Hou, Ying;  Guo, Xiuli; et al.
Favorite | TC[WOS]:8 TC[Scopus]:10  IF:3.2/3.3 | Submit date：2022/05/17
Apoptosis  Colon Cancer  Jnk1/2  Chinese Medicine  Psoralidin  Ros  
Nagilactone E increases PD-L1 expression through activation of c-Jun in lung cancer cells Journal article
CHEN,Yu Chi, HUANG,Mu Yang, ZHANG,Le Le, FENG,Zhe Ling, JIANG,Xiao Ming, YUAN,Luo Wei, HUANG,Run Yue, LIU,Bo, YU,Hua, WANG,Yi Tao, CHEN,Xiu Ping, LIN,Li Gen, LU,Jin Jian. Nagilactone E increases PD-L1 expression through activation of c-Jun in lung cancer cells[J]. Chinese Journal of Natural Medicines, 2020, 18(7), 517-525.
Authors:  CHEN,Yu Chi;  HUANG,Mu Yang;  ZHANG,Le Le;  FENG,Zhe Ling;  JIANG,Xiao Ming; et al.
Favorite | TC[WOS]:15 TC[Scopus]:15  IF:4.0/3.7 | Submit date：2021/03/01
Programmed Death Ligand 1  Nagilactone e  Lung Cancer  C-jun  Jnk  
Dual role of oxidative stress-JNK activation in autophagy and apoptosis induced by nickel oxide nanoparticles in human cancer cells Journal article
Cho,Yik Lam, Tan,Hayden Weng Siong, Saquib,Quaiser, Ren,Yi, Ahmad,Javed, Wahab,Rizwan, He,Weifeng, Bay,Boon Huat, Shen,Han Ming. Dual role of oxidative stress-JNK activation in autophagy and apoptosis induced by nickel oxide nanoparticles in human cancer cells[J]. Free Radical Biology and Medicine, 2020, 153, 173-186.
Authors:  Cho,Yik Lam;  Tan,Hayden Weng Siong;  Saquib,Quaiser;  Ren,Yi;  Ahmad,Javed; et al.
Favorite | TC[WOS]:27 TC[Scopus]:28  IF:7.1/7.9 | Submit date：2021/03/02
Apoptosis  Autophagy  Jnk  Nio-nps  Oxidative Stress  Ros  
Phanginin R induces cytoprotective autophagy via JNK/C-JUN signaling pathway in non-small cell lung cancer A549 cells Journal article
Zhang, Le-Le, Bao,Han, Xu, Yu-Lian, Jiang, Xiao-Ming, Li, Wei, Zou,Liang, Lin, Li-Gen, Lu,Jin-Jian. Phanginin R induces cytoprotective autophagy via JNK/C-JUN signaling pathway in non-small cell lung cancer A549 cells[J]. Anti-Cancer Agents in Medicinal Chemistry, 2020, 20(8), 982-988.
Authors:  Zhang, Le-Le;  Bao,Han;  Xu, Yu-Lian;  Jiang, Xiao-Ming;  Li, Wei; et al.
Favorite | TC[WOS]:3 TC[Scopus]:4  IF:2.6/2.5 | Submit date：2021/03/01
Anti-cancer  Autophagy  C-jun  Jnk  Non-small Cell Lung Cancer  Phanginin r  
Ribosome-inactivating protein α-momorcharin derived from edible plant momordica charantia induces inflammatory responses by activating the NF-kappaB and JNK pathways Journal article
Chen,Ying Jie, Zhu,Jia Qian, Fu,Xiu Qiong, Su,Tao, Li,Ting, Guo,Hui, Zhu,Pei Li, Lee,Sally Kin Wah, Yu,Hua, Tse,Anfernee Kai Wing, Yu,Zhi Ling. Ribosome-inactivating protein α-momorcharin derived from edible plant momordica charantia induces inflammatory responses by activating the NF-kappaB and JNK pathways[J]. Toxins, 2019, 11(12), 694.
Authors:  Chen,Ying Jie;  Zhu,Jia Qian;  Fu,Xiu Qiong;  Su,Tao;  Li,Ting; et al.
Favorite | TC[WOS]:11 TC[Scopus]:15  IF:3.9/4.2 | Submit date：2021/03/02
Alpha-momorcharin  Inflammation  Jnk  Nf-kappab  Ribosome Inactivating Protein  
Acetaminophen-induced liver injury is attenuated in transgenic fat-1 mice endogenously synthesizing long-chain n-3 fatty acids Journal article
Feng, Ruibing, Wang, Yang, Liu, Conghui, Yan, Chunyan, Zhang, Hang, Su, Huanxing, Kang, Jing X., Shang, Chang-Zhen, Wan, Jim-Bo. Acetaminophen-induced liver injury is attenuated in transgenic fat-1 mice endogenously synthesizing long-chain n-3 fatty acids[J]. BIOCHEMICAL PHARMACOLOGY, 2018, 154, 75-88.
Authors:  Feng, Ruibing;  Wang, Yang;  Liu, Conghui;  Yan, Chunyan;  Zhang, Hang; et al.
Favorite | TC[WOS]:17 TC[Scopus]:21  IF:5.3/5.2 | Submit date：2018/10/30
Acetaminophen  N-3 Polyunsaturated Fatty Acids  Hepatotoxicity  Jnk  Inflammatory