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Artemisinin inhibits neuronal ferroptosis in Alzheimer's disease models by targeting KEAP1 Journal article
Peng-xi Deng, Marta Silva, Na Yang, Qing Wang, Xin Meng, Ke-qiang Ye, Hong-chang Gao, ZHENG WENHUA. Artemisinin inhibits neuronal ferroptosis in Alzheimer's disease models by targeting KEAP1[J]. Acta Pharmacologica Sinica, 2024.
Authors:  Peng-xi Deng;  Marta Silva;  Na Yang;  Qing Wang;  Xin Meng; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:6.9/7.6 | Submit date：2024/08/31
Alzheimer's Disease  Artemisinin  Ferroptosis  Keap1  Nrf2  Hippocampus  
Artemisinin protects against neural injury by targeting KEAP1 to inhibit ferroptosis in Alzheimer’s disease models Conference paper
Pengxi DENG, ZHENG WENHUA. Artemisinin protects against neural injury by targeting KEAP1 to inhibit ferroptosis in Alzheimer’s disease models[C], 2024.
Authors:  Pengxi DENG;  ZHENG WENHUA
Favorite |  | Submit date：2024/08/31
Artemisinin, Ferroptosis, Keap1, Nrf2, Alzheimer's Disease (Ad).  
Small molecule deoxynyboquinone triggers alkylation and ubiquitination of Keap1 at Cys489 on Kelch domain for Nrf2 activation and inflammatory therapy Journal article
Linghu, Ke-Gang, Zhang, Tian, Zhang, Guang-Tao, Lv, Peng, Zhang, Wenjun, Zhao, Guanding, Xiong, Shihong, Zhao, Mingming, Chen, Meiwan, HU YUANJIA, Zhang, Changsheng, Yu, Hua. Small molecule deoxynyboquinone triggers alkylation and ubiquitination of Keap1 at Cys489 on Kelch domain for Nrf2 activation and inflammatory therapy[J]. Journal of Pharmaceutical Analysis, 2024, 14(3), 401-415.
Authors:  Linghu, Ke-Gang;  Zhang, Tian;  Zhang, Guang-Tao;  Lv, Peng;  Zhang, Wenjun; et al.
Favorite | TC[WOS]:6 TC[Scopus]:9  IF:6.1/6.8 | Submit date：2024/01/02
Deoxynyboquinone  Anti-inflammation  Target  Keap1/nrf2  Alkylation  Ubiquitination  
Germacrane-type sesquiterpenoids from the flowers of Chrysanthemum indicum with hepatoprotective activity Journal article
Liu, Yu, Zhou, Fei, Shu, Hongzhen, Lin, Ligen, Zhang, Qingwen. Germacrane-type sesquiterpenoids from the flowers of Chrysanthemum indicum with hepatoprotective activity[J]. Food and Chemical Toxicology, 2023, 177, 113850.
Authors:  Liu, Yu;  Zhou, Fei;  Shu, Hongzhen;  Lin, Ligen;  Zhang, Qingwen
Favorite | TC[WOS]:0 TC[Scopus]:1  IF:3.9/4.5 | Submit date：2023/08/03
Chrysanthemum Indicum  Germacrane-type Sesquiterpenoids  Hepatoprotection  Kelch Domain Of Keap1  Nrf2  
Dehydroeburicoic Acid, a Dual Inhibitor against Oxidative Stress in Alcoholic Liver Disease Journal article
Shasha Cheng, Yi Kuang, Guodong Li, Jia Wu, Chung-Nga Ko, Wanhe Wang, Dik-Lung Ma, Min Ye, Chung-Hang Leung. Dehydroeburicoic Acid, a Dual Inhibitor against Oxidative Stress in Alcoholic Liver Disease[J]. Pharmaceuticals, 2022, 16(1), 14.
Authors:  Shasha Cheng;  Yi Kuang;  Guodong Li;  Jia Wu;  Chung-Nga Ko; et al.
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:4.3/4.6 | Submit date：2023/02/08
Alcoholic Liver Disease (Ald)  Glycogen Synthase Kinase 3β (Gsk3β)  Hepatoprotective  Keap1–nrf2 Protein–protein Interaction (Ppi)  
7-deacetyl-gedunin suppresses proliferation of Human rheumatoid arthritis synovial fibroblast through activation of Nrf2/ARE signaling Journal article
Chen, Jian Yu, Zhu, Guo Yuan, Sun, Yi Bin, Wu, Yue Chan, Wu, Bao Kun, Zheng, Wan Ting, Ma, Xue Qin, Zheng, Yan Fang. 7-deacetyl-gedunin suppresses proliferation of Human rheumatoid arthritis synovial fibroblast through activation of Nrf2/ARE signaling[J]. International Immunopharmacology, 2022, 107.
Authors:  Chen, Jian Yu;  Zhu, Guo Yuan;  Sun, Yi Bin;  Wu, Yue Chan;  Wu, Bao Kun; et al.
Favorite | TC[WOS]:22 TC[Scopus]:22  IF:4.8/5.0 | Submit date：2023/01/30
7-deacetyl-gedunin  Arthritis  Ho-1  Keap1  Mh7a  Nrf2  P62  Rasfs