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Modeling on in vivo disposition and cellular transportation of RNA lipid nanoparticles via quantum mechanics/physiologically-based pharmacokinetic approaches Journal article
Wang, Wei, Deng, Shiwei, Lin, Jinzhong, Ouyang, Defang. Modeling on in vivo disposition and cellular transportation of RNA lipid nanoparticles via quantum mechanics/physiologically-based pharmacokinetic approaches[J]. Acta Pharmaceutica Sinica B, 2024, 14(10), 4591-4607.
Authors:  Wang, Wei;  Deng, Shiwei;  Lin, Jinzhong;  Ouyang, Defang
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:14.7/14.1 | Submit date：2024/09/03
Lipid Nanoparticle  Rna  Ionizable Lipid  In Vivo Transportation  Endosomal Escape  Metabolism  Quantum Mechanics  Physiologically-based Pharmacokinetics  
Development of in silico methodology for siRNA lipid nanoparticle formulations Journal article
Gao, Haoshi, Kan, Stanislav, Ye, Zhuyifan, Feng, Yuchen, Jin, Lei, Zhang, Xudong, Deng, Jiayin, Chan, Ging, Hu, Yuanjia, Wang, Yongjun, Cao, Dongsheng, Ji, Yuanhui, Liang, Mingtao, Li, Haifeng, Ouyang, Defang. Development of in silico methodology for siRNA lipid nanoparticle formulations[J]. Chemical Engineering Journal, 2022, 442, 136310.
Authors:  Gao, Haoshi;  Kan, Stanislav;  Ye, Zhuyifan;  Feng, Yuchen;  Jin, Lei; et al.
Favorite | TC[WOS]:15 TC[Scopus]:16  IF:13.3/13.2 | Submit date：2022/05/13
Cationic Lipids  Knockdown Efficiency  Lipid Nanoparticle  Machine Learning  Molecular Dynamic Simulation  Sirna  
Intravital lipid droplet labeling and imaging reveals the phenotypes and functions of individual macrophages in vivo Journal article
Li, Yue, Du, Yuwei, Xu, Zhengqing, He, Yuan, Yao, Ran, Jiang, Huiran, Ju, Wen, Qiao, Jianlin, Xu, Kailin, Liu, Tzu Ming, Zeng, Lingyu. Intravital lipid droplet labeling and imaging reveals the phenotypes and functions of individual macrophages in vivo[J]. Journal of lipid research, 2022, 63(5), 100207.
Authors:  Li, Yue;  Du, Yuwei;  Xu, Zhengqing;  He, Yuan;  Yao, Ran; et al.
Adobe PDF | Favorite | TC[WOS]:4 TC[Scopus]:5  IF:5.0/5.7 | Submit date：2022/08/02
Biomarker  Bone Marrow  Fatty Acid Analog  Inflammation  In vivo Imaging  Lipid Droplet  Lipid Trafficking  Macrophage  Nanoparticle Delivery  Systemic Inflammation  
Prediction of lipid nanoparticles for mRNA vaccines by the machine learning algorithm Journal article
Wang, Wei, Feng, Shuo, Ye, Zhuyifan, Gao, Hanlu, Lin, Jinzhong, Ouyang, Defang. Prediction of lipid nanoparticles for mRNA vaccines by the machine learning algorithm[J]. Acta Pharmaceutica Sinica B, 2021, 12(6), 2950 - 2962.
Authors:  Wang, Wei;  Feng, Shuo;  Ye, Zhuyifan;  Gao, Hanlu;  Lin, Jinzhong; et al.
Favorite | TC[WOS]:55 TC[Scopus]:58  IF:14.7/14.1 | Submit date：2022/05/17
Formulation Prediction  Ionizable Lipid  Lightgbm  Lipid Nanoparticle  Machine Learning  Molecular Modeling  Mrna  Vaccine