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Structure-based identification of a NEDD8-activating enzyme inhibitor via drug repurposing Journal article
Wu, Ke-Jia, Zhong, Hai-Jing, Li, Guodong, Liu, Chenfu, Wang, Hui-Min David, Ma, Dik-Lung, Leung, Chung-Hang. Structure-based identification of a NEDD8-activating enzyme inhibitor via drug repurposing[J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 143, 1021-1027.
Authors:  Wu, Ke-Jia;  Zhong, Hai-Jing;  Li, Guodong;  Liu, Chenfu;  Wang, Hui-Min David; et al.
Favorite | TC[WOS]:51 TC[Scopus]:53  IF:6.0/6.1 | Submit date:2018/10/30
Drug Repurposing  Mitoxantrone  Nedd8  Ubiquitin  
Nedd8 modification of Cullin-5 regulates lipopolysaccharide-induced acute lung injury Journal article
Zhu, Ziyan, Sun, Lei, Hao, Rui, Jiang, Hongchao, Qian, Feng, Ye, Richard D.. Nedd8 modification of Cullin-5 regulates lipopolysaccharide-induced acute lung injury[J]. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2017, 313(1), L104-L114.
Authors:  Zhu, Ziyan;  Sun, Lei;  Hao, Rui;  Jiang, Hongchao;  Qian, Feng; et al.
Favorite | TC[WOS]:26 TC[Scopus]:26  IF:3.6/4.4 | Submit date:2018/10/30
Cullin-5  Macrophage  Nedd8  Acute Lung Injury  
Discovery of deoxyvasicinone derivatives as inhibitors of NEDD8-activating enzyme Journal article
Zhong H.-J., Leung K.-H., Lin S., Chan D.S.-H., Han Q.-B., Chan S.L.-F., Ma D.-L., Leung C.-H.. Discovery of deoxyvasicinone derivatives as inhibitors of NEDD8-activating enzyme[J]. Methods, 2015, 71(C), 71-76.
Authors:  Zhong H.-J.;  Leung K.-H.;  Lin S.;  Chan D.S.-H.;  Han Q.-B.; et al.
Favorite | TC[WOS]:21 TC[Scopus]:21 | Submit date:2018/11/06
Deoxyvasicinone  Drug Discovery  Nedd8  Pharmacophore  Ubiquitin-like