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Anti-inflammatory bicyclic polyprenylated acylphloroglucinols with diverse architectures including an unprecedented 6/6/6 tricyclic core from Garcinia yunnanensis Journal article
Hu, Xin Yue, Luo, Hui Juan, Wei, Xin, Wang, Yu Zhuo, Ye, Yan Song, Wan, Shi Jie, Zheng, Dan, Zhou, Yu, Xu, Hong Xi, Li, Xing Ren, Lin, Li Gen, Xu, Gang. Anti-inflammatory bicyclic polyprenylated acylphloroglucinols with diverse architectures including an unprecedented 6/6/6 tricyclic core from Garcinia yunnanensis[J]. Bioorganic Chemistry, 2024, 153, 107864.
Authors:  Hu, Xin Yue;  Luo, Hui Juan;  Wei, Xin;  Wang, Yu Zhuo;  Ye, Yan Song; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:4.5/4.7 | Submit date：2024/11/05
1l-1β  Anti-inflammatory Activity  Bpap  Garcinia Yunnanensis  Nlrp3  
Regulation of NLRP3 inflammasome and Caspase-3/4/11 by 2′,4′-dihydroxychalcone contributes to anti-colorectal cancer Journal article
Zhang, Guohui, Yao, Yixin, Zhang, Zhongyu, Xiao, Jian, Yu, Hua, Zhao, Jinmin, Yao, Chun, Wang, Yitao, Luo, Hua. Regulation of NLRP3 inflammasome and Caspase-3/4/11 by 2′,4′-dihydroxychalcone contributes to anti-colorectal cancer[J]. Phytomedicine, 2024, 135, 156194.
Authors:  Zhang, Guohui;  Yao, Yixin;  Zhang, Zhongyu;  Xiao, Jian;  Yu, Hua; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:6.7/6.2 | Submit date：2024/12/05
2′,4′–dihydroxychalcone  Abrus Cantoniensis Hance  Colorectal Cancer  Nlrp3  Pyroptosis  
Dehydroervatamine as a promising novel TREM2 agonist, attenuates neuroinflammation Journal article
Li, Lin, Xu, Nan, He, Yulin, Tang, Mingsui, Yang, Binrui, Du, Jun, Chen, Liang, Mao, Xiaowen, Song, Bing, Hua, Zhou, Tang, Benqin, Lee, Simon Ming yuen. Dehydroervatamine as a promising novel TREM2 agonist, attenuates neuroinflammation[J]. Neurotherapeutics, 2024, e00479.
Authors:  Li, Lin;  Xu, Nan;  He, Yulin;  Tang, Mingsui;  Yang, Binrui; et al.
Favorite | TC[Scopus]:0  IF:5.6/6.9 | Submit date：2024/12/26
Neuroinflammation  19,20-dehydroervatamine  Trem2  Nf-κb  Nlrp3  
Heme oxygenase 1-mediated ferroptosis in Kupffer cells initiates liver injury during heat stroke Journal article
Li, Ru, Wei, Riqing, Liu, Chenxin, Zhang, Keying, He, Sixiao, Liu, Zhifeng, Huang, Junhao, Tang, Youyong, An, Qiyuan, Lin, Ligen, Gan, Lishe, Zhao, Liying, Zou, Xiaoming, Wang, Fudi, Ping, Yuan, Ma, Qiang. Heme oxygenase 1-mediated ferroptosis in Kupffer cells initiates liver injury during heat stroke[J]. Acta Pharmaceutica Sinica B, 2024, 14(9), 3983-4000.
Authors:  Li, Ru;  Wei, Riqing;  Liu, Chenxin;  Zhang, Keying;  He, Sixiao; et al.
Favorite | TC[WOS]:6 TC[Scopus]:7  IF:14.7/14.1 | Submit date：2024/07/04
Heat Stroke  Liver Injury  Kupffer Cells  Ferroptosis  Heme Oxygenase 1  Phosphatidylinositol 4-kinase Beta  Nlrp3  Early Growth Response Factor 1  
Discovery of natural product derivative triptolidiol as a direct NLRP3 inhibitor by reducing K63-specific ubiquitination Journal article
Ding Moyu, Ning Chengqing, Chen Shaoru, Yin Haoran, Xu Jing, WANG YING. Discovery of natural product derivative triptolidiol as a direct NLRP3 inhibitor by reducing K63-specific ubiquitination[J]. doi: 10.1111/bph.17320, 2024, 181(22), 1–18.
Authors:  Ding Moyu;  Ning Chengqing;  Chen Shaoru;  Yin Haoran;  Xu Jing; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:6.8/7.4 | Submit date：2024/10/06
Immunosuppressive Activity  Inflammasome-driven Disease  K63-linked Ubiquitination,  Nlrp3  Triptolide Derivative  Triptolidiol  
Exploring the anti-inflammatory ingredients and potential of golden buckwheat (Fagopyrum dibotrys) on the TLR4/NLRP3 pathway in acute lung injury Journal article
Hu, Yingfan, Liu, Xiaomin, Song, Yu, Zhang, Yan, Li, Wei, Zhang, Lele, Wang, Anqi, Su, Qian, Yang, Zhiyong, Zou, Liang. Exploring the anti-inflammatory ingredients and potential of golden buckwheat (Fagopyrum dibotrys) on the TLR4/NLRP3 pathway in acute lung injury[J]. Food Science and Nutrition, 2024.
Authors:  Hu, Yingfan;  Liu, Xiaomin;  Song, Yu;  Zhang, Yan;  Li, Wei; et al.
Favorite | TC[WOS]:0 TC[Scopus]:1  IF:3.5/4.2 | Submit date：2024/05/16
Acute Lung Injury  Anti-inflammatory  Fagopyrum Dibotrys  Golden Buckwheat  Tlr4/nlrp3  
Upregulation of Nrf2 signaling: A key molecular mechanism of Baicalin's neuroprotective action against diabetes-induced cognitive impairment Journal article
Zheng, Yanfang, Wang, Chenxiang, Liu, Wenjing, Chen, Jiaying, Sun, Yibin, Chang, Dennis, Wang, Huan, Xu, Wen, Lu, Jin Jian, Zhou, Xian, Huang, Mingqing. Upregulation of Nrf2 signaling: A key molecular mechanism of Baicalin's neuroprotective action against diabetes-induced cognitive impairment[J]. Biomedicine and Pharmacotherapy, 2024, 174, 116579.
Authors:  Zheng, Yanfang;  Wang, Chenxiang;  Liu, Wenjing;  Chen, Jiaying;  Sun, Yibin; et al.
Favorite | TC[WOS]:3 TC[Scopus]:4  IF:6.9/6.8 | Submit date：2024/05/16
Baicalin  Diabetes-associated Cognitive Deficits  Keap1-nrf2  Neuroinflammation  Nlrp3 Inflammasome  Oxidative Stress  
Quercetin as a promising intervention for rat osteoarthritis by decreasing M1-polarized macrophages via blocking the TRPV1-mediated P2X7/NLRP3 signaling pathway Journal article
Li, Wenjun, He, Hebei, Du, Min, Gao, Mu, Sun, Qijie, Wang, Yeyang, Lu, Hanyu, Ou, Shuanji, Xia, Changliang, Xu, Changpeng, Zhao, Qi, Sun, Hongtao. Quercetin as a promising intervention for rat osteoarthritis by decreasing M1-polarized macrophages via blocking the TRPV1-mediated P2X7/NLRP3 signaling pathway[J]. Phytotherapy Research, 2024, 38(4), 1990-2006.
Authors:  Li, Wenjun;  He, Hebei;  Du, Min;  Gao, Mu;  Sun, Qijie; et al.
Favorite | TC[WOS]:7 TC[Scopus]:6  IF:6.1/7.0 | Submit date：2024/11/05
M1 Macrophage Polarization  Nlrp3  Osteoarthritis  P2x7  Quercetin  Trpv1  
Quercetin as a promising intervention for rat osteoarthritis by decreasing M1‐polarized macrophages via blocking the TRPV1‐mediated P2X7/NLRP3 signaling pathway Journal article
Li Wenjun, He Hebei, Du Min, Gao Mu, Sun Qijie, Wang Yeyang, Lu Hanyu, Ou Shuanji, Xin Changliang, Xu Changpeng, Zhao Qi, Sun Hongtao. Quercetin as a promising intervention for rat osteoarthritis by decreasing M1‐polarized macrophages via blocking the TRPV1‐mediated P2X7/NLRP3 signaling pathway[J]. Phytotherapy research, 2024, 38(4), 1990-2006.
Authors:  Li Wenjun;  He Hebei;  Du Min;  Gao Mu;  Sun Qijie; et al.
Adobe PDF | Favorite | TC[WOS]:7 TC[Scopus]:6  IF:6.1/7.0 | Submit date：2024/03/18
M1 Macrophage Polarization  Nlrp3  Osteoarthritis  P2x7  Quercetin  Trpv1  
Limonoids from the roots of Melia azedarach and their anti-inflammatory activity Journal article
Song, Min, Luo, Hui Juan, Li, Zi Wei, Qiu, Ling, Zhao, Yu Xin, He, Cheng Wei, Zhang, Xiao Qi, Ye, Wen Cai, Lin, Li Gen, Zhang, Qing Wen. Limonoids from the roots of Melia azedarach and their anti-inflammatory activity[J]. Phytochemistry, 2023, 216, 113869.
Authors:  Song, Min;  Luo, Hui Juan;  Li, Zi Wei;  Qiu, Ling;  Zhao, Yu Xin; et al.
Favorite | TC[WOS]:3 TC[Scopus]:4  IF:3.2/3.4 | Submit date：2024/01/02
1l-1β  Anti-inflammatory Activity  Limonoids  MeL.a Azedarach L.  Nlrp3