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Tetramethylpyrazine nitrone exerts neuroprotection via activation of PGC-1α/Nrf2 pathway in Parkinson's disease models
Journal article
Guo, Baojian, Zheng, Chengyou, Cao, Jie, Luo, Fangcheng, Li, Haitao, Hu, Shengquan, Mingyuan Lee, Simon, Yang, Xifei, Zhang, Gaoxiao, Zhang, Zaijun, Sun, Yewei, Wang, Yuqiang. Tetramethylpyrazine nitrone exerts neuroprotection via activation of PGC-1α/Nrf2 pathway in Parkinson's disease models[J]. Journal of Advanced Research, 2024, 64, 195-211.
Authors:
Guo, Baojian
;
Zheng, Chengyou
;
Cao, Jie
;
Luo, Fangcheng
;
Li, Haitao
; et al.
Favorite
|
TC[WOS]:
5
TC[Scopus]:
5
IF:
11.4
/
11.0
|
Submit date:2024/02/22
Nuclear Factor Erythroid-2-related Factor 2
Parkinson's Disease
Peroxisome Proliferator-activated Receptor γ Co-activator 1α
Tetramethylpyrazine Nitrone
The PTM profiling of CTCF reveals the regulation of 3D chromatin structure by O-GlcNAcylation
Journal article
Tang, Xiuxiao, Zeng, Pengguihang, Liu, Kezhi, Qing, Li, Sun, Yifei, Liu, Xinyi, Lu, Lizi, Wei, Chao, Wang, Jia, Jiang, Shaoshuai, Sun, Jun, Chang, Wakam, Yu, Haopeng, Chen, Hebing, Zhou, Jiaguo, Xu, Chengfang, Fan, Lili, Miao, Yi Liang, Ding, Junjun. The PTM profiling of CTCF reveals the regulation of 3D chromatin structure by O-GlcNAcylation[J]. Nature Communications, 2024, 15(1), 2813.
Authors:
Tang, Xiuxiao
;
Zeng, Pengguihang
;
Liu, Kezhi
;
Qing, Li
;
Sun, Yifei
; et al.
Favorite
|
TC[WOS]:
5
TC[Scopus]:
4
IF:
14.7
/
16.1
|
Submit date:2024/05/16
Ccctc-binding-factor
Differential Expression
Phosphorylation Sites
Nuclear Factor
Genome
Gene
Pluripotency
Domains
Dna
Identification
Tetramethylpyrazine Nitrone Promotes the Clearance of Alpha-Synuclein via Nrf2-Mediated Ubiquitin–Proteasome System Activation
Journal article
Guo, Baojian, Zheng, Chengyou, Cao, Jie, Qiu, Xiaoling, Luo, Fangcheng, Li, Haitao, Lee, Simon Mingyuan, Yang, Xifei, Zhang, Gaoxiao, Sun, Yewei, Zhang, Zaijun, Wang, Yuqiang. Tetramethylpyrazine Nitrone Promotes the Clearance of Alpha-Synuclein via Nrf2-Mediated Ubiquitin–Proteasome System Activation[J]. NeuroMolecular Medicine, 2024, 26(1), 9.
Authors:
Guo, Baojian
;
Zheng, Chengyou
;
Cao, Jie
;
Qiu, Xiaoling
;
Luo, Fangcheng
; et al.
Favorite
|
TC[WOS]:
1
TC[Scopus]:
1
IF:
3.3
/
3.6
|
Submit date:2024/05/16
Nuclear Factor Erythroid-2-related Factor 2
Parkinson’s Disease
Peroxisome Proliferator-activated Receptor γ Co-activator 1α
Tetramethylpyrazine Nitrone
Ubiquitin–proteasome System
Α-synuclein
Rubiginosin B selectively inhibits Treg cell differentiation and enhances anti-tumor immune responses by targeting calcineurin-NFAT signaling pathway
Journal article
Geng,Chang An, Chen,Feng Yang, Zheng,Jing Bin, Liao,Ping, Li,Tian Ze, Zhang,Xue Mei, Chen,Xin*, Chen,Ji Jun. Rubiginosin B selectively inhibits Treg cell differentiation and enhances anti-tumor immune responses by targeting calcineurin-NFAT signaling pathway[J]. Phytomedicine, 2023, 116, 154898.
Authors:
Geng,Chang An
;
Chen,Feng Yang
;
Zheng,Jing Bin
;
Liao,Ping
;
Li,Tian Ze
; et al.
Favorite
|
TC[WOS]:
4
TC[Scopus]:
4
IF:
6.7
/
6.2
|
Submit date:2023/08/03
Calcineurin
cd4+foxp3+ Regulatory t Cells (Tregs)
Nuclear Factor Of Activated t Cells (Nfat)
Rhododendron Brachypodum
Rubiginosin b (Rgb)
Tumor Microenvironment
15, 16-Dihydrotanshinone I protects against ischemic stroke by inhibiting ferroptosis via the activation of nuclear factor erythroid 2-related factor 2
Journal article
Chuanhong Wu, Feipeng Duan, Ruocong Yang, Yaolan Dai, Xiuping Chen, Shaojing Li. 15, 16-Dihydrotanshinone I protects against ischemic stroke by inhibiting ferroptosis via the activation of nuclear factor erythroid 2-related factor 2[J]. Phytomedicine, 2023, 114, 154790.
Authors:
Chuanhong Wu
;
Feipeng Duan
;
Ruocong Yang
;
Yaolan Dai
;
Xiuping Chen
; et al.
Favorite
|
TC[WOS]:
21
TC[Scopus]:
21
IF:
6.7
/
6.2
|
Submit date:2023/07/19
15, 16-dihydrotanshinone i
Ferroptosis
Ischemic Stroke
Nuclear Factor Erythroid 2-related Factor 2
Src homology 3 domain binding kinase 1 protects against hepatic steatosis and insulin resistance through the Nur77–FGF21 pathway
Journal article
Ahuja, Palak, Bi, Xinyi, Ng, Chun Fai, Tse, Margaret Chui Ling, Hang, Miaojia, Pang, Brian Pak Shing, Iu, Elsie Chit Yu, Chan, Wing Suen, Ooi, Xin Ci, Sun, Anqi, Herlea-Pana, Oana, Liu, Zhixue, Yang, Xiuying, Jiao, Baowei, Ma, Xin, Wu, Kelvin Ka Lok, Lee, Leo Tsz On, Cheng, Kenneth King Yip, Lee, Chi Wai, Chan, Chi Bun. Src homology 3 domain binding kinase 1 protects against hepatic steatosis and insulin resistance through the Nur77–FGF21 pathway[J]. Hepatology, 2023, 77(1), 213-229.
Authors:
Ahuja, Palak
;
Bi, Xinyi
;
Ng, Chun Fai
;
Tse, Margaret Chui Ling
;
Hang, Miaojia
; et al.
Favorite
|
TC[WOS]:
11
TC[Scopus]:
11
IF:
12.9
/
15.5
|
Submit date:2022/05/17
Growth-factor 21
Orphan Nuclear Receptors
Transcriptional Regulators
Metabolic-activity
Beta-klotho
Expression
Fgf21
Phosphorylation
Activation
Obesity
Atypical IκB Bcl3 enhances the generation of the NF-κB p52 homodimer
Journal article
Wenfei Pan, Limei Deng, Haitao Wang, Vivien Ya-Fan Wang. Atypical IκB Bcl3 enhances the generation of the NF-κB p52 homodimer[J]. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2022, 10, 930619.
Authors:
Wenfei Pan
;
Limei Deng
;
Haitao Wang
;
Vivien Ya-Fan Wang
Favorite
|
TC[WOS]:
7
TC[Scopus]:
7
IF:
4.6
/
5.2
|
Submit date:2022/08/22
Nf-κb—nuclear Factor-kappa b
Dimerization
Bcl3
Nf-κb:Iκb Complex
Gene Expression
Establishment of a High Content Image Platform to Measure NF-κB Nuclear Translocation in LPS-induced RAW264.7 Macrophages for Screening Anti-inflammatory Drug Candidates
Journal article
Zhang, Yan Yu, Yao, Yun Da, Cheng, Qi Qing, Huang, Yu Feng, Zhou, Hua. Establishment of a High Content Image Platform to Measure NF-κB Nuclear Translocation in LPS-induced RAW264.7 Macrophages for Screening Anti-inflammatory Drug Candidates[J]. Current Drug Metabolism, 2022, 23(5), 394-414.
Authors:
Zhang, Yan Yu
;
Yao, Yun Da
;
Cheng, Qi Qing
;
Huang, Yu Feng
;
Zhou, Hua
Favorite
|
TC[WOS]:
2
TC[Scopus]:
3
IF:
2.1
/
2.9
|
Submit date:2023/01/30
Anti-inflammation
Bay 11-7085
Benzoylhypaconine
High Content Image
Lipopolysaccharide
Nuclear Factor-κb Nuclear Translocation
Raw264.7 Macrophages
A bioactive ligand-conjugated iridium(III) metal-based complex as a Keap1–Nrf2 protein-protein interaction inhibitor against acetaminophen-induced acute liver injury
Journal article
Li, Guodong, Liu, Hao, Feng, Ruibing, Kang, Tian Shu, Wang, Wanhe, Ko, Chung Nga, Wong, Chun Yuen, Ye, Min, Ma, Dik Lung, Wan, Jian Bo, Leung, Chung Hang. A bioactive ligand-conjugated iridium(III) metal-based complex as a Keap1–Nrf2 protein-protein interaction inhibitor against acetaminophen-induced acute liver injury[J]. Redox Biology, 2021, 48, 102129.
Authors:
Li, Guodong
;
Liu, Hao
;
Feng, Ruibing
;
Kang, Tian Shu
;
Wang, Wanhe
; et al.
Favorite
|
TC[WOS]:
28
TC[Scopus]:
31
IF:
10.7
/
11.7
|
Submit date:2022/05/13
Inhibitor
Iridium(Iii) Complex
Kelch-like Ech-associated Protein 1
Liver Injury
Nuclear Factor E2-related Factor 2
Sigesbeckia glabrescens Makino extract attenuated the collagen-induced arthritis through inhibiting the synovial hyperplasia and inflammation
Journal article
Ma,Qiu Shuo, Linghu,Ke Gang, Zhang,Tian, Zhao,Guan Ding, Xiong,Wei, Xiong,Shi Hang, Zhao,Mingming, Xu,Wei, Yu,Juan, Yu,Hua. Sigesbeckia glabrescens Makino extract attenuated the collagen-induced arthritis through inhibiting the synovial hyperplasia and inflammation[J]. Chinese Medicine, 2020, 15(1), 91.
Authors:
Ma,Qiu Shuo
;
Linghu,Ke Gang
;
Zhang,Tian
;
Zhao,Guan Ding
;
Xiong,Wei
; et al.
Favorite
|
TC[WOS]:
2
TC[Scopus]:
3
IF:
5.3
/
5.5
|
Submit date:2021/03/02
Inflammation
Nuclear Transcription Factor-kappa b
Rheumnnatoid Arthritis
Sigesbeckia Glabrescens Makino
Sw982
Synovial Hyperplasia