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Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants Journal article
Li, Linjie, Shi, Kaiyuan, Gu, Yuhang, Xu, Zepeng, Shu, Chang, Li, Dedong, Sun, Junqing, Cong, Mengqing, Li, Xiaomei, Zhao, Xin, Yu, Guanghui, Hu, Songnian, Tan, Hui, Qi, Jianxun, Ma, Xiaopeng, Liu, Kefang, Gao, George F.. Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants[J]. Structure, 2024, 32(8), 1055-1067.e6.
Authors:  Li, Linjie;  Shi, Kaiyuan;  Gu, Yuhang;  Xu, Zepeng;  Shu, Chang; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:4.4/4.3 | Submit date：2024/08/05
Ba.2.86  Eg.5  Eg.5.1  Hace2  Hv.1  Jn.1  Rbd  Sars-cov-2  
Neutralization of EG.5, EG.5.1, BA.2.86, and JN.1 by antisera from dimeric receptor-binding domain subunit vaccines and 41 human monoclonal antibodies Journal article
He, Qingwen, An, Yaling, Zhou, Xuemei, Xie, Haitang, Tao, Lifeng, Li, Dedong, Zheng, Anqi, Li, Linjie, Xu, Zepeng, Yu, Shufan, Wang, Ruyue, Hu, Hua, Liu, Kefang, Wang, Qihui, Dai, Lianpan, Xu, Kun, Gao, George F.. Neutralization of EG.5, EG.5.1, BA.2.86, and JN.1 by antisera from dimeric receptor-binding domain subunit vaccines and 41 human monoclonal antibodies[J]. Med, 2024, 5(5), 401-413.e4.
Authors:  He, Qingwen;  An, Yaling;  Zhou, Xuemei;  Xie, Haitang;  Tao, Lifeng; et al.
Favorite | TC[WOS]:3 TC[Scopus]:4 | Submit date：2024/05/16
Ba.2.86  Eg.5  Eg.5.1  Immune Evasion  Jn.1  Neutralizing Antibody  Rbd-dimer  Sars-cov-2  Translation To Humans  Zf2001 Vaccine  Zf2202-a  
Structural basis of increased binding affinities of spikes from SARS-CoV-2 Omicron variants to rabbit and hare ACE2s reveals the expanding host tendency Journal article
Shi, Kaiyuan, Li, Linjie, Luo, Chunliang, Xu, Zepeng, Huang, Baihan, Ma, Sufang, Liu, Kefang, Yu, Guanghui, Gao, George F.. Structural basis of increased binding affinities of spikes from SARS-CoV-2 Omicron variants to rabbit and hare ACE2s reveals the expanding host tendency[J]. mBio, 2024, 15(2), e02988-23.
Authors:  Shi, Kaiyuan;  Li, Linjie;  Luo, Chunliang;  Xu, Zepeng;  Huang, Baihan; et al.
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:5.1/5.9 | Submit date：2024/03/07
Ace2  Cryo-em Structure  Hare  Rabbit  Rbd  Sars-cov  Sars-cov-2  Spike (s) Proteins  
Defining a de novo non-RBM antibody as RBD-8 and its synergistic rescue of immune-evaded antibodies to neutralize Omicron SARS-CoV-2 Journal article
Rao, Xia, Zhao, Runchu, Tong, Zhou, Guo, Shuxin, Peng, Weiyu, Liu, Kefang, Li, Shihua, Wu, Lili, Tong, Jianyu, Chai, Yan, Han, Pu, Wang, Feiran, Jia, Peng, Li, Zhaohui, Zhao, Xin, Li, Dedong, Zhang, Rong, Zhang, Xue, Zou, Weiwei, Li, Weiwei, Wang, Qihui, Gao, George Fu, Wu, Yan, Dai, Lianpan, Gao, Feng. Defining a de novo non-RBM antibody as RBD-8 and its synergistic rescue of immune-evaded antibodies to neutralize Omicron SARS-CoV-2[J]. Proceedings of the National Academy of Sciences of the United States of America, 2023, 120(52), e2314193120.
Authors:  Rao, Xia;  Zhao, Runchu;  Tong, Zhou;  Guo, Shuxin;  Peng, Weiyu; et al.
Favorite | TC[WOS]:8 TC[Scopus]:9  IF:9.4/10.8 | Submit date：2024/01/02
Cryptic Epitope  Neutralizing Antibody  Omicron Ba.4/ba.5/bq.1.1/xbb Subvariant  Rbd-8  Sars-cov-2  
Classification of five SARS-CoV-2 serotypes based on RBD antigenicities Journal article
Hu, Shixiong, Wu, Chunli, Wu, Xinkai, Ma, Xuehui, Shu, Chang, Chen, Qian, Zheng, Anqi, Yang, Huiting, Lu, Jian, Du, Pei, Gao, George Fu, Wang, Qihui. Classification of five SARS-CoV-2 serotypes based on RBD antigenicities[J]. Science Bulletin, 2023, 68(23), 3003-3012.
Authors:  Hu, Shixiong;  Wu, Chunli;  Wu, Xinkai;  Ma, Xuehui;  Shu, Chang; et al.
Favorite | TC[WOS]:9 TC[Scopus]:12  IF:18.8/15.8 | Submit date：2024/02/22
Mrna Vaccine  Receptor-binding Domain (Rbd)  Sars-cov-2  Serotype Classification  Spike (s)  
Structural basis of white-tailed deer, Odocoileus virginianus, ACE2 recognizing all the SARS-CoV-2 variants of concern with high affinity Journal article
Han, Pu, Meng, Yumin, Zhang, Di, Xu, Zepeng, Li, Zhiyuan, Pan, Xiaoqian, Zhao, Zhennan, Li, Linjie, Tang, Lingfeng, Qi, Jianxun, Liu, Kefang, Gao, George F.. Structural basis of white-tailed deer, Odocoileus virginianus, ACE2 recognizing all the SARS-CoV-2 variants of concern with high affinity[J]. Journal of Virology, 2023, 97(9), e00505.
Authors:  Han, Pu;  Meng, Yumin;  Zhang, Di;  Xu, Zepeng;  Li, Zhiyuan; et al.
Favorite | TC[WOS]:5 TC[Scopus]:6  IF:4.0/4.0 | Submit date：2024/01/10
Ace2  Cryo-em Structure  Odocoileus Virginianus  Rbd  s Proteins  Sars-cov-2  White-tailed Deer  
Host range and structural analysis of bat-origin RshSTT182/200 coronavirus binding to human ACE2 and its animal orthologs Journal article
Hu, Yu, Liu, Kefang, Han, Pu, Xu, Zepeng, Zheng, Anqi, Pan, Xiaoqian, Jia, Yunfei, Su, Chao, Tang, Lingfeng, Wu, Lili, Bai, Bin, Zhao, Xin, Tian, Di, Chen, Zhihai, Qi, Jianxun, Wang, Qihui, Gao, George F.. Host range and structural analysis of bat-origin RshSTT182/200 coronavirus binding to human ACE2 and its animal orthologs[J]. EMBO Journal, 2023, 42(4).
Authors:  Hu, Yu;  Liu, Kefang;  Han, Pu;  Xu, Zepeng;  Zheng, Anqi; et al.
Favorite | TC[WOS]:8 TC[Scopus]:8  IF:9.4/11.0 | Submit date：2023/03/06
Ace2  Interspecies Transmission  Rbd  Rshstt182/200  Sars-cov-2  
Protective prototype-Beta and Delta-Omicron chimeric RBD-dimer vaccines against SARS-CoV-2 Journal article
Xu, Kun, Gao, Ping, Liu, Sheng, Lu, Shuaiyao, Lei, Wenwen, Zheng, Tianyi, Liu, Xueyuan, Xie, Yufeng, Zhao, Zhennan, Guo, Shuxin, Tang, Cong, Yang, Yun, Yu, Wenhai, Wang, Junbin, Zhou, Yanan, Huang, Qing, Liu, Chuanyu, An, Yaling, Zhang, Rong, Han, Yuxuan, Duan, Minrun, Wang, Shaofeng, Yang, Chenxi, Wu, Changwei, Liu, Xiaoya, She, Guangbiao, Liu, Yan, Zhao, Xin, Xu, Ke, Qi, Jianxun, Wu, Guizhen, Peng, Xiaozhong, Dai, Lianpan, Wang, Peiyi, Gao, George F.. Protective prototype-Beta and Delta-Omicron chimeric RBD-dimer vaccines against SARS-CoV-2[J]. Cell, 2022, 185(13), 2265-2278.e14.
Authors:  Xu, Kun;  Gao, Ping;  Liu, Sheng;  Lu, Shuaiyao;  Lei, Wenwen; et al.
Favorite | TC[WOS]:84 TC[Scopus]:88  IF:45.5/49.0 | Submit date：2022/08/02
Covid19 Vaccine  Delta Variant  Immunogen Structure  Omicron Variant  Rbd  Receptor-binding Domain  Sars-cov-2  Vaccine Protection  Variant Of Concern  Voc  
2-Bromo-3-((1-(7-chloroquinolin-4-yl)-1H-1,2,3-triazol-4-yl)-methoxy)-benzaldehyde Journal article
Yun, Xiaoyun, Xie, Yuhan, Ng, Jerome P.L., Law, Betty Yuen Kwan, Wong, Vincent Kam Wai, Coghi, Paolo. 2-Bromo-3-((1-(7-chloroquinolin-4-yl)-1H-1,2,3-triazol-4-yl)-methoxy)-benzaldehyde[J]. MolBank, 2022, 2022(1).
Authors:  Yun, Xiaoyun;  Xie, Yuhan;  Ng, Jerome P.L.;  Law, Betty Yuen Kwan;  Wong, Vincent Kam Wai; et al.
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:0.6/0.4 | Submit date：2022/09/21
1,2,3-triazole  Bio-layer Interferometry  Rbd  Sars-cov-2  
Receptor binding and complex structures of human ACE2 to spike RBD from omicron and delta SARS-CoV-2 Journal article
Han, Pengcheng, Li, Linjie, Liu, Sheng, Wang, Qisheng, Zhang, Di, Xu, Zepeng, Han, Pu, Li, Xiaomei, Peng, Qi, Su, Chao, Huang, Baihan, Li, Dedong, Zhang, Rong, Tian, Mingxiong, Fu, Lutang, Gao, Yuanzhu, Zhao, Xin, Liu, Kefang, Qi, Jianxun, Gao, George F., Wang, Peiyi. Receptor binding and complex structures of human ACE2 to spike RBD from omicron and delta SARS-CoV-2[J]. Cell, 2022, 185(4), 630-640.
Authors:  Han, Pengcheng;  Li, Linjie;  Liu, Sheng;  Wang, Qisheng;  Zhang, Di; et al.
Favorite | TC[WOS]:317 TC[Scopus]:328  IF:45.5/49.0 | Submit date：2022/03/04
Delta  Hace2  Omicron  Rbd  Receptor-binding Domain  Structure  Variants Of Concern  Vocs