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Atavistic strategy for the treatment of hyperuricemia via ionizable liposomal mRNA Journal article
Zhang, Mengjie, Hussain, Abid, Hu, Bo, Yang, Haiyin, Li, Chunhui, Guo, Shuai, Han, Xiaofeng, Li, Bei, Dai, Yunlu, Cao, Yuhong, Chi, Hang, Weng, Yuhua, Qin, Cheng Feng, Huang, Yuanyu. Atavistic strategy for the treatment of hyperuricemia via ionizable liposomal mRNA[J]. Nature Communications, 2024, 15(1), 6463.
Authors:  Zhang, Mengjie;  Hussain, Abid;  Hu, Bo;  Yang, Haiyin;  Li, Chunhui; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:14.7/16.1 | Submit date：2024/09/03
Serum Uric-acid  Urate Oxidase  Delivery  Sirna  Risk  Endocytosis  Therapy  
Delivery of therapeutic small interfering RNA: The current patent-based landscape Journal article
Chen, Yu, Xiong, Shi Hang, Li, Fei, Kong, Xiang Jun, Ouyang, De Fang, Zheng, Ying, Yu, Hua, Hu, Yuan Jia. Delivery of therapeutic small interfering RNA: The current patent-based landscape[J]. Molecular Therapy - Nucleic Acids, 2022, 29, 150-161.
Authors:  Chen, Yu;  Xiong, Shi Hang;  Li, Fei;  Kong, Xiang Jun;  Ouyang, De Fang; et al.
Favorite | TC[WOS]:4 TC[Scopus]:6  IF:6.5/6.7 | Submit date：2023/06/29
Delivery Technology  Patent Landscape  Therapeutic Sirna  
Development of in silico methodology for siRNA lipid nanoparticle formulations Journal article
Gao, Haoshi, Kan, Stanislav, Ye, Zhuyifan, Feng, Yuchen, Jin, Lei, Zhang, Xudong, Deng, Jiayin, Chan, Ging, Hu, Yuanjia, Wang, Yongjun, Cao, Dongsheng, Ji, Yuanhui, Liang, Mingtao, Li, Haifeng, Ouyang, Defang. Development of in silico methodology for siRNA lipid nanoparticle formulations[J]. Chemical Engineering Journal, 2022, 442, 136310.
Authors:  Gao, Haoshi;  Kan, Stanislav;  Ye, Zhuyifan;  Feng, Yuchen;  Jin, Lei; et al.
Favorite | TC[WOS]:15 TC[Scopus]:16  IF:13.3/13.2 | Submit date：2022/05/13
Cationic Lipids  Knockdown Efficiency  Lipid Nanoparticle  Machine Learning  Molecular Dynamic Simulation  Sirna  
Acid-activatible micelleplex delivering siRNA-PD-L1 for improved cancer immunotherapy of CDK4/6 inhibition Journal article
Gao, Jing, Zhang, Hanwu, Zhou, Fengqi, Hou, Bo, Chen, Meiwan, Xie, Zhigang, Yu, Haijun. Acid-activatible micelleplex delivering siRNA-PD-L1 for improved cancer immunotherapy of CDK4/6 inhibition[J]. Chinese Chemical Letters, 2021, 32(6), 1929-1936.
Authors:  Gao, Jing;  Zhang, Hanwu;  Zhou, Fengqi;  Hou, Bo;  Chen, Meiwan; et al.
Favorite | TC[WOS]:35 TC[Scopus]:34  IF:9.4/7.3 | Submit date：2021/12/08
Acid-activatible Micelleplex  Cancer Immunotherapy  Cdk4/6 Inhibitor  Pd-l1 Knockdown  Sirna Delivery  
Developing effective siRNAs to reduce the expression of key viral genes of COVID-19 Journal article
Wu, R., Luo, K.Q.. Developing effective siRNAs to reduce the expression of key viral genes of COVID-19[J]. International Journal of Biological Sciences, 2021, 1521-1529.
Authors:  Wu, R.;  Luo, K.Q.
Favorite |   IF:8.2/8.3 | Submit date：2022/08/26
COVID-19  SARS-CoV-2  RNA secondary structure  siRNA  gene silencing  
Developing effective siRNAs to reduce the expression of key viral genes of covid-19 Journal article
Wu, Renfei, Luo, Kathy Qian. Developing effective siRNAs to reduce the expression of key viral genes of covid-19[J]. International Journal of Biological Sciences, 2021, 17(6), 1521-1529.
Authors:  Wu, Renfei;  Luo, Kathy Qian
Favorite | TC[WOS]:18 TC[Scopus]:19  IF:8.2/8.3 | Submit date：2022/05/13
Covid-19  Gene Silencing  Rna Secondary Structure  Sars-cov-2  Sirna  
Suppression of c-jun influences nNOS expression in differentiated PC12 cells Journal article
Cheng X., Liu S., Wang Y.-Q., Li Y.-Q., Fu R., Tang Y., Zheng W.-H., Zhou L.-H.. Suppression of c-jun influences nNOS expression in differentiated PC12 cells[J]. Molecular Medicine Reports, 2012, 6(4), 750-754.
Authors:  Cheng X.;  Liu S.;  Wang Y.-Q.;  Li Y.-Q.;  Fu R.; et al.
Favorite | TC[WOS]:6 TC[Scopus]:6 | Submit date：2018/12/21
C-jun  Differentiated Pc12 Cells  Neuronal Nitric Oxide Synthase  Sirna  
Hydrotalcite intercalated siRNA: Computational characterization of the interlayer environment Journal article
Zhang H., Ouyang D., Murthy V., Wong Y., Xu Z., Smith S.C.. Hydrotalcite intercalated siRNA: Computational characterization of the interlayer environment[J]. Pharmaceutics, 2012, 4(2), 296-313.
Authors:  Zhang H.;  Ouyang D.;  Murthy V.;  Wong Y.;  Xu Z.; et al.
Favorite | TC[Scopus]:8 | Submit date：2019/01/15
Gene Therapy  Layered Double Hydroxide  Molecular Dynamics Simulations  Sirna Delivery  
The effect of pH on PAMAM dendrimer-siRNA complexation - Endosomal considerations as determined by molecular dynamics simulation Journal article
Ouyang D., Zhang H., Parekh H.S., Smith S.C.. The effect of pH on PAMAM dendrimer-siRNA complexation - Endosomal considerations as determined by molecular dynamics simulation[J]. Biophysical Chemistry, 2011, 158(2-3), 126-133.
Authors:  Ouyang D.;  Zhang H.;  Parekh H.S.;  Smith S.C.
Favorite | TC[WOS]:76 TC[Scopus]:81 | Submit date：2019/01/15
Dendrimer  Endosome  Gene Delivery  Molecular Dynamics Simulation  Proton Sponge Theory  Sirna  
A critical role of IFNγ in priming MSC-mediated suppression of T cell proliferation through up-regulation of B7-H1 Journal article
Sheng H., Wang Y., Jin Y., Zhang Q., Zhang Y., Wang L., Shen B., Yin S., Liu W., Cui L., Li N.. A critical role of IFNγ in priming MSC-mediated suppression of T cell proliferation through up-regulation of B7-H1[J]. Cell Research, 2008, 18(8), 846-857.
Authors:  Sheng H.;  Wang Y.;  Jin Y.;  Zhang Q.;  Zhang Y.; et al.
Favorite | TC[WOS]:314 TC[Scopus]:341 | Submit date：2019/01/16
B7-h1  Ifnγ  Immunosuppression  Mesenchymal Stem Cells (Mscs)  Proliferation Inhibition  Sirna