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A small molecule cryptotanshinone induces non-enzymatic NQO1-dependent necrosis in cancer cells through the JNK1/2/Iron/PARP/calcium pathway Journal article
Hou, Ying, Zhong, Bingling, Zhao, Lin, Wang, Heng, Zhu, Yanyan, Wang, Xianzhe, Zheng, Haoyi, Yu, Jie, Liu, Guokai, Wang, Xin, Martin-Garcia, Jose M., Chen, Xiuping. A small molecule cryptotanshinone induces non-enzymatic NQO1-dependent necrosis in cancer cells through the JNK1/2/Iron/PARP/calcium pathway[J]. Acta Pharmaceutica Sinica B, 2025.
Authors:  Hou, Ying;  Zhong, Bingling;  Zhao, Lin;  Wang, Heng;  Zhu, Yanyan; et al.
Favorite | TC[Scopus]:0  IF:14.7/14.1 | Submit date：2025/01/22
Calcium  Cancer  Cryptotanshinone  Ferroptosis  Iron  Nad++ Depletion  Nqo1  Targeted Therapy  
Identify critical genes of breast cancer and corresponding leading natural product compounds of potential therapeutic targets Journal article
Fan, Xiaokai, Xin, Le, Yu, Xuan, Liu, Maoxuan, Shim, Joong Sup, Yang, Gui, Chen, Liang. Identify critical genes of breast cancer and corresponding leading natural product compounds of potential therapeutic targets[J]. Molecular Diversity, 2024.
Authors:  Fan, Xiaokai;  Xin, Le;  Yu, Xuan;  Liu, Maoxuan;  Shim, Joong Sup; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:3.9/3.5 | Submit date：2024/12/26
Breast Cancer  Hub Genes  Leading Compounds  Targeted Therapy  
Metal-Phenolic Nanomaterial with Organelle-Level Precision Primes Antitumor Immunity via mtDNA-dependent cGAS-STING Activation Journal article
Tian, Hao, Li, Wenxi, Wang, Guohao, Tian, Ye, Yan, Jie, Yu, Xinying, Yan, Ziliang, Feng, Yuzhao, Dai, Yunlu. Metal-Phenolic Nanomaterial with Organelle-Level Precision Primes Antitumor Immunity via mtDNA-dependent cGAS-STING Activation[J]. Angewandte Chemie - International Edition, 2024, e202411498.
Authors:  Tian, Hao;  Li, Wenxi;  Wang, Guohao;  Tian, Ye;  Yan, Jie; et al.
Favorite | TC[WOS]:0 TC[Scopus]:4  IF:16.1/16.2 | Submit date：2024/11/05
Photodynamic Therapy  Mitochondria-targeted Pdt  Polyphenols  Mtdna Damages  Cgas-sting Pathway  
NIR-II excitation self-assembly nanomedicine for targeted NIR-IIa fluorescence imaging-guided cuproptosis-promoted synergistic therapy against triple-negative breast cancer Journal article
Dai Yeneng, Leng Dongliang, Guo Ziang, Wang Jiaqi, Gu Yuheng, Peng Yingjun, Zhu Lipeng, Zhao Qi. NIR-II excitation self-assembly nanomedicine for targeted NIR-IIa fluorescence imaging-guided cuproptosis-promoted synergistic therapy against triple-negative breast cancer[J]. Chemical Engineering Journal, 2024, 479, 147704.
Authors:  Dai Yeneng;  Leng Dongliang;  Guo Ziang;  Wang Jiaqi;  Gu Yuheng; et al.
Adobe PDF | Favorite | TC[WOS]:26 TC[Scopus]:9  IF:13.3/13.2 | Submit date：2024/01/25
Nir-ii Excitation  Self-assembly  Amplified Cuproptosis  Nir-iia Fluorescence Imaging  Targeted Therapy  
Inhibition of USP7 upregulates USP22 and activates its downstream cancer-related signaling pathways in human cancer cells Journal article
Zhang, Keqiang, Sun, Ting, Li, Wendong, Guo, Yuming, Li, Aimin, Hsieh, Marcus, Wang, Jinghan, Wu, Jun, Arvanitis, Leonidas, Raz, Dan J.. Inhibition of USP7 upregulates USP22 and activates its downstream cancer-related signaling pathways in human cancer cells[J]. Cell Communication and Signaling, 2023, 21, 319.
Authors:  Zhang, Keqiang;  Sun, Ting;  Li, Wendong;  Guo, Yuming;  Li, Aimin; et al.
Favorite | TC[WOS]:3 TC[Scopus]:2  IF:8.2/8.0 | Submit date：2024/01/02
C-myc  Deubiquitinase  P53  Sp1  Targeted Anticancer Therapy  Usp22  Usp7  
A target map of clinical combination therapies in oncology: an analysis of clinicaltrials.gov Journal article
Yang, Jing, Kang, Heming, Lyu, Liyang, Xiong, Wei, Hu, Yuanjia. A target map of clinical combination therapies in oncology: an analysis of clinicaltrials.gov[J]. Discover Oncology, 2023, 14(1), 151.
Authors:  Yang, Jing;  Kang, Heming;  Lyu, Liyang;  Xiong, Wei;  Hu, Yuanjia
Favorite | TC[WOS]:8 TC[Scopus]:7 | Submit date：2023/09/21
Bispecific Antibodies  Combination Therapy  Immuno-oncology Therapy  Kinase Inhibitors  Pd-1/pd-l1 Inhibitors  Targeted Therapy  
Extracellular vesicles: a rising star for therapeutics and drug delivery Journal article
Shuang Du, Yucheng Guan, Aihua Xie, Zhao Yan, Sijia Gao, Weirong Li, Lang Rao, Xiaojia Chen, Tongkai Chen. Extracellular vesicles: a rising star for therapeutics and drug delivery[J]. Journal of Nanobiotechnology, 2023, 21(1), 231.
Authors:  Shuang Du;  Yucheng Guan;  Aihua Xie;  Zhao Yan;  Sijia Gao; et al.
Favorite | TC[WOS]:65 TC[Scopus]:72  IF:10.6/11.4 | Submit date：2023/08/03
Clinical Challenges  Drug Loading  Extracellular Vesicles  Neurodegenerative Diseases  Surface Modification  Targeted Therapy  
Breast tumor-targeted drug delivery via polymer nanocarriers: Endogenous and exogenous strategies Journal article
Zhu,Mengfan, Wang,Xunhao, Zhou,Yan, Li,Mengmeng, Wang,Yufei, Wang,Yinhan, Li,Tengfei, Song,Sean Yan, Zhang,Boxin, Hezam,Kamal, Zhang,Jin. Breast tumor-targeted drug delivery via polymer nanocarriers: Endogenous and exogenous strategies[J]. Journal of Applied Polymer Science, 2023, 140(31), e54227.
Authors:  Zhu,Mengfan;  Wang,Xunhao;  Zhou,Yan;  Li,Mengmeng;  Wang,Yufei; et al.
Favorite | TC[WOS]:9 TC[Scopus]:9  IF:2.7/2.8 | Submit date：2023/08/03
Breast Cancer Therapy  Hydrogel  Micelle  Nanocarriers  Targeted Delivery  
Editorial: New mechanistic insights into cancer precision medicine Other
2023-02-16
Authors:  Kwok,Hang Fai
Favorite | TC[WOS]:0 TC[Scopus]:0 | Submit date：2023/08/03
Immunotherapy  Targeted Therapy  Therapeutic Antibody  Chemotherapy  Novel Bioactive Molecule  Biomarker  Drug Resistance  
Multiple initiatives to conquer KRAS G12C inhibitor resistance from the perspective of clinical therapy Journal article
Zhang JunMin, Zhang JuanHong, Leung Elaine Lai Han, Yao XiaoJun. Multiple initiatives to conquer KRAS G12C inhibitor resistance from the perspective of clinical therapy[J]. EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2023, 32(2), 101-106.
Authors:  Zhang JunMin;  Zhang JuanHong;  Leung Elaine Lai Han;  Yao XiaoJun
Favorite | TC[WOS]:2 TC[Scopus]:3  IF:4.9/5.3 | Submit date：2023/06/15
Kras G12c  Amg 510  Mrtx 849  Targeted Therapy  Drug Resistance