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Coculture of cancer cells with platelets increases their survival and metastasis by activating the TGFβ/Smad/PAI-1 and PI3K/AKT pathways Journal article
Tong, Haibo, Li, Koukou, Zhou, Muya, Wu, Ranfei, Yang, Hongmei, Peng, Zheng, Zhao, Qi, Luo, Kathy Qian. Coculture of cancer cells with platelets increases their survival and metastasis by activating the TGFβ/Smad/PAI-1 and PI3K/AKT pathways[J]. International Journal of Biological Sciences, 2023, 19(13), 4259-4277.
Authors:  Tong, Haibo;  Li, Koukou;  Zhou, Muya;  Wu, Ranfei;  Yang, Hongmei; et al.
Favorite | TC[WOS]:5 TC[Scopus]:7  IF:8.2/8.3 | Submit date：2023/08/23
Cancer Cells  Platelets  Survival  Metastasis  Tgfβ  Pai-1  
Intracellular mRNA phase separation induced by cationic polymers for tumor immunotherapy Journal article
Xing, Zhen, Xue, Jing, Ma, Xindian, Han, Congwei, Wang, Zhenzhen, Luo, Shunhuang, Wang, Chunming, Dong, Lei, Zhang, Junfeng. Intracellular mRNA phase separation induced by cationic polymers for tumor immunotherapy[J]. JOURNAL OF NANOBIOTECHNOLOGY, 2022, 20(1), 442.
Authors:  Xing, Zhen;  Xue, Jing;  Ma, Xindian;  Han, Congwei;  Wang, Zhenzhen; et al.
Favorite | TC[WOS]:5 TC[Scopus]:6  IF:10.6/11.4 | Submit date：2023/01/30
Cationic Polymers  Immunotherapy  Mrna Phase Separation  Tgfβ1  Tumor Microenvironment  
β-Carboline Alkaloids From the Deep-Sea Fungus Trichoderma sp. MCCC 3A01244 as a New Type of Anti-pulmonary Fibrosis Agent That Inhibits TGF-β/Smad Signaling Pathway Journal article
Hao, Meng Jiao, Chen, Pei Nan, Li, Hou Jin, Wu, Feng, Zhang, Guang Yu, Shao, Zong Ze, Liu, Xiu Pian, Ma, Wen Zhe, Xu, Jun, Mahmud, Taifo, Lan, Wen Jian. β-Carboline Alkaloids From the Deep-Sea Fungus Trichoderma sp. MCCC 3A01244 as a New Type of Anti-pulmonary Fibrosis Agent That Inhibits TGF-β/Smad Signaling Pathway[J]. Frontiers in Microbiology, 2022, 13.
Authors:  Hao, Meng Jiao;  Chen, Pei Nan;  Li, Hou Jin;  Wu, Feng;  Zhang, Guang Yu; et al.
Favorite | TC[WOS]:14 TC[Scopus]:17  IF:4.0/5.1 | Submit date：2023/01/30
Acid-directed Strategy  Anti-pulmonary Fibrosis  Tgf-β/smad  Trichoderma  Β-carboline Alkaloids  
miR-7/TGF-β2 axis sustains acidic tumor microenvironment-induced lung cancer metastasis Journal article
Su, Tao, Huang, Suchao, Zhang, Yanmin, Guo, Yajuan, Zhang, Shuwei, Guan, Jiaji, Meng, Mingjing, Liu, Linxin, Wang, Caiyan, Yu, Dihua, Kwan, Hiu Yee, Huang, Zhiying, Huang, Qiuju, Lai-Han Leung, Elaine, Hu, Ming, Wang, Ying, Liu, Zhongqiu, Lu, Linlin. miR-7/TGF-β2 axis sustains acidic tumor microenvironment-induced lung cancer metastasis[J]. Acta Pharmaceutica Sinica B, 2022, 12(2), 821-837.
Authors:  Su, Tao;  Huang, Suchao;  Zhang, Yanmin;  Guo, Yajuan;  Zhang, Shuwei; et al.
Favorite | TC[WOS]:18 TC[Scopus]:21  IF:14.7/14.1 | Submit date：2023/01/30
Acidic Tumor Microenvironment  Invasion  Lung Cancer  Metastasis  Mir-7-5p  Ph  Tgf-β2  
(±)-Atrachinenins A—C, Three Pairs of Caged C27 Meroterpenoids from the Rhizomes of Atractylodes chinensis Journal article
Chen, Fei Long, Liu, Dong Li, Fu, Jing, Yang, Ji, Bai, Li Ping, Zhang, Wei, Jiang, Zhi Hong, Zhu, Guo Yuan. (±)-Atrachinenins A—C, Three Pairs of Caged C27 Meroterpenoids from the Rhizomes of Atractylodes chinensis[J]. Chinese Journal of Chemistry, 2021, 40(4), 460-466.
Authors:  Chen, Fei Long;  Liu, Dong Li;  Fu, Jing;  Yang, Ji;  Bai, Li Ping; et al.
Favorite | TC[WOS]:10 TC[Scopus]:9  IF:5.5/5.2 | Submit date：2023/01/30
Atractylodes Chinensis  Terpenoids  Phytochemistry  Natural Products  Tgf-beta  
Cisplatin prevents breast cancer metastasis through blocking early EMT and retards cancer growth together with paclitaxel Journal article
Wang,Haitao, Guo,Sen, Kim,Seung Jin, Shao,Fangyuan, Kei Ho,Joshua Wing, Wong,Kuan Un, Miao,Zhengqiang, Hao,Dapeng, Zhao,Ming, Xu,Jun, Zeng,Jianming, Wong,Koon Ho, Di,Lijun, Wong,Ada Hang Heng, Xu,Xiaoling, Deng,Chu Xia. Cisplatin prevents breast cancer metastasis through blocking early EMT and retards cancer growth together with paclitaxel[J]. Theranostics, 2021, 11(5), 2442-2459.
Authors:  Wang,Haitao;  Guo,Sen;  Kim,Seung Jin;  Shao,Fangyuan;  Kei Ho,Joshua Wing; et al.
Favorite | TC[WOS]:66 TC[Scopus]:75  IF:12.4/12.0 | Submit date：2021/03/02
Cisplatin  Metastasis  Neoadjuvant Therapy  Paclitaxel  Tgfβ  
Natural alkaloid 8-oxo-epiberberine inhibited TGF-β1-triggred epithelial-mesenchymal transition by interfering Smad3 Journal article
Liu,Xin, Zhang,Yiying, ZHOU,Guang Ju, Hou,Ying, Kong,Qi, Lu,Jin Jian, Zhang,Qingwen, Chen,Xiuping. Natural alkaloid 8-oxo-epiberberine inhibited TGF-β1-triggred epithelial-mesenchymal transition by interfering Smad3[J]. TOXICOLOGY AND APPLIED PHARMACOLOGY, 2020, 404, 115179.
Authors:  Liu,Xin;  Zhang,Yiying;  ZHOU,Guang Ju;  Hou,Ying;  Kong,Qi; et al.
Favorite | TC[WOS]:14 TC[Scopus]:14  IF:3.3/3.6 | Submit date：2021/03/01
Emt  Metastasis  Tgf-β1  Chinese Medicine  
TGFβ2-mediated epithelial–mesenchymal transition and NF-κB pathway activation contribute to osimertinib resistance Journal article
Jiang,Xiao ming, Xu,Yu lian, Yuan,Luo wei, Zhang,Le le, Huang,Mu yang, Ye,Zi han, Su,Min xia, Chen,Xiu ping, Zhu,Hong, Ye,Richard D., Lu,Jin jian. TGFβ2-mediated epithelial–mesenchymal transition and NF-κB pathway activation contribute to osimertinib resistance[J]. Acta Pharmacologica Sinica, 2020, 42(3), 451-459.
Authors:  Jiang,Xiao ming;  Xu,Yu lian;  Yuan,Luo wei;  Zhang,Le le;  Huang,Mu yang; et al.
Favorite | TC[WOS]:40 TC[Scopus]:39  IF:6.9/7.6 | Submit date：2021/03/01
Egfr Mutant Non-small Cell Lung Cancer  Emt  Nf-κb  Osimertinib Resistance  Tgfβ2  
TGFβ2-mediated epithelial-mesenchymal transition and NF-κB pathway activation contribute to osimertinib resistance Journal article
Jiang, XM, Xu, YL, Yuan, LW, Zhang, LL, Huang, MY, Ye, ZH, Su, MX, Chen, X. P., Zhu, H, Ye, R, Lu, J.. TGFβ2-mediated epithelial-mesenchymal transition and NF-κB pathway activation contribute to osimertinib resistance[J]. Acta Pharmacologica Sinica, 2020, 451-459.
Authors:  Jiang, XM;  Xu, YL;  Yuan, LW;  Zhang, LL;  Huang, MY; et al.
Favorite |  | Submit date：2022/08/26
Egfr Mutant Non-small Cell Lung Cancer  Nf-κb  Tgfβ2  Epithelial-mesenchymal Transition  Osimertinib Resistance  
Novel venom-based peptides (P13 & its derivative -- M6) to maintain self-renewal of human embryonic stem cells by activating FGF and TGF-ß signaling pathways Journal article
Ma, R., Ren, Z., Li, B., Siu, W. I., Chen, G., Kwok, H. F.. Novel venom-based peptides (P13 & its derivative -- M6) to maintain self-renewal of human embryonic stem cells by activating FGF and TGF-ß signaling pathways[J]. Stem Cell Research & Therapy, 2020, 11(1), 243.
Authors:  Ma, R.;  Ren, Z.;  Li, B.;  Siu, W. I.;  Chen, G.; et al.
Favorite | TC[WOS]:4 TC[Scopus]:4  IF:7.1/7.9 | Submit date：2022/06/02
Venom-based Peptide  Stem Cell Application  Fgfr And Tgfβ Receptors