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Immunosuppressive regulatory cells in cancer immunotherapy: restrain or modulate? Review article
2024
Authors:  Wu, Yan;  Chen, Dongfeng;  Gao, Yang;  Xu, Qinggang;  Zhou, Yang; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:3.4/3.4 | Submit date：2024/07/04
Immunoregulatory Cells  Immunotherapy  Mdscs  Safety  Tregs  
Immunosuppressive regulatory cells in cancer immunotherapy: restrain or modulate? Journal article
Wu, Yan, Chen, Dongfeng, Gao, Yang, Xu, Qinggang, Zhou, Yang, Ni, Zhong, Na, Manli. Immunosuppressive regulatory cells in cancer immunotherapy: restrain or modulate?[J]. Human Cell, 2024, 37(4), 931-943.
Authors:  Wu, Yan;  Chen, Dongfeng;  Gao, Yang;  Xu, Qinggang;  Zhou, Yang; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:3.4/3.4 | Submit date：2024/09/03
Immunoregulatory cells  Immunotherapy  MDSCs  Safety  Tregs  
Rubiginosin B selectively inhibits Treg cell differentiation and enhances anti-tumor immune responses by targeting calcineurin-NFAT signaling pathway Journal article
Geng,Chang An, Chen,Feng Yang, Zheng,Jing Bin, Liao,Ping, Li,Tian Ze, Zhang,Xue Mei, Chen,Xin*, Chen,Ji Jun. Rubiginosin B selectively inhibits Treg cell differentiation and enhances anti-tumor immune responses by targeting calcineurin-NFAT signaling pathway[J]. Phytomedicine, 2023, 116, 154898.
Authors:  Geng,Chang An;  Chen,Feng Yang;  Zheng,Jing Bin;  Liao,Ping;  Li,Tian Ze; et al.
Favorite | TC[WOS]:3 TC[Scopus]:3  IF:6.7/6.2 | Submit date：2023/08/03
Calcineurin  cd4+foxp3+ Regulatory t Cells (Tregs)  Nuclear Factor Of Activated t Cells (Nfat)  Rhododendron Brachypodum  Rubiginosin b (Rgb)  Tumor Microenvironment  
Anti-TNFR2 enhanced the antitumor activity of a new HMGN1/3M-052 stimulated dendritic cell vaccine in a mouse model of colon cancer Journal article
Zhu, Lan, Zhang, Xiangyan, Chen, Xin, Yang, De, Nie, Yujie, Pan, Runsang, Li, Linzhao, Wang, Chenglv, Gui, Huan, Chen, Shuanghui, Jing, Qianyu, Wang, Mengjiao, Nie, Yingjie. Anti-TNFR2 enhanced the antitumor activity of a new HMGN1/3M-052 stimulated dendritic cell vaccine in a mouse model of colon cancer[J]. Biochemical and Biophysical Research Communications, 2023, 653, 106-114.
Authors:  Zhu, Lan;  Zhang, Xiangyan;  Chen, Xin;  Yang, De;  Nie, Yujie; et al.
Favorite | TC[WOS]:6 TC[Scopus]:5  IF:2.5/2.7 | Submit date：2023/05/02
Anti-tnfr2  Antitumor  cd4+foxp3+regulatory t Cells (Tregs)  Dendritic Cells (Dcs)  Hmgn1 And 3m-052  Immunotherapy  
Exosome-Modified Liposomes Targeted Delivery of Thalidomide to Regulate Treg Cells for Antitumor Immunotherapy Journal article
Yang,Yang, Wang,Qingfu, Zou,Huimin, Chou Chon-Kit, Chen Xin*. Exosome-Modified Liposomes Targeted Delivery of Thalidomide to Regulate Treg Cells for Antitumor Immunotherapy[J]. Pharmaceutics, 2023, 15(4), 1074.
Authors:  Yang,Yang;  Wang,Qingfu;  Zou,Huimin;  Chou Chon-Kit;  Chen Xin*
Favorite | TC[WOS]:5 TC[Scopus]:5  IF:4.9/5.5 | Submit date：2023/08/03
Exosome  Regulatory t Cells (Tregs)  Thalidomide  Tnfr2  
TNFR2 antagonistic antibody induces the death of tumor infiltrating CD4+Foxp3+ regulatory T cells Journal article
He, Tianzhen, Chen, Yibo, Yang, De, Islam, Md Sahidul, Chou, Chon Kit, Liu, Jiarui, Faustman, Denise L., Oppenheim, Joost J., Chen, Xin*. TNFR2 antagonistic antibody induces the death of tumor infiltrating CD4+Foxp3+ regulatory T cells[J]. Cellular Oncology, 2022, 46(1), 167-177.
Authors:  He, Tianzhen;  Chen, Yibo;  Yang, De;  Islam, Md Sahidul;  Chou, Chon Kit; et al.
Favorite | TC[WOS]:7 TC[Scopus]:6  IF:4.9/5.2 | Submit date：2023/01/30
cd4+foxp3+ Regulatory t Cells (Tregs)  Cell Death  Lymphoma  Tnfr2  Tnfr2 Antagonistic Antibody  
SCM-198 Alleviates Endometriosis by Suppressing Estrogen-ERα mediated Differentiation and Function of CD4+CD25+ Regulatory T Cells Journal article
Li, Yun Yun, Lin, Yi Kong, Li, Yue, Liu, Xin Hua, Li, Da Jin, Wang, Xiao Lin, Wang, Li, Zhu, Yi Zhun, Yu, Min, Du, Mei Rong. SCM-198 Alleviates Endometriosis by Suppressing Estrogen-ERα mediated Differentiation and Function of CD4+CD25+ Regulatory T Cells[J]. International Journal of Biological Sciences, 2022, 18(5), 1961-1973.
Authors:  Li, Yun Yun;  Lin, Yi Kong;  Li, Yue;  Liu, Xin Hua;  Li, Da Jin; et al.
Favorite | TC[WOS]:10 TC[Scopus]:10  IF:8.2/8.3 | Submit date：2023/01/30
Ems  Erα  Estrogen  Scm-198  Tregs  
A TNFR2 antibody by countering immunosuppression cooperates with HMGN1 and R848 immune stimulants to inhibit murine colon cancer Journal article
Jiang, Mengmeng, Liu, Jia, Yang, De, Tross, Debra, Li, Ping, Chen, Fengyang, Alam, Md Masud, Faustman, Denise L., Oppenheim, Joost J., Chen, Xin. A TNFR2 antibody by countering immunosuppression cooperates with HMGN1 and R848 immune stimulants to inhibit murine colon cancer[J]. International Immunopharmacology, 2021, 101, 108345.
Authors:  Jiang, Mengmeng;  Liu, Jia;  Yang, De;  Tross, Debra;  Li, Ping; et al.
Favorite | TC[WOS]:22 TC[Scopus]:22  IF:4.8/5.0 | Submit date：2021/12/08
Antitumor  cd4+foxp3+ Regulatory t Cells (Tregs)  Hmgn1 And R848  Immunotherapy  Tnfr2  
Cyclophosphamide abrogates the expansion of CD4+Foxp3+ regulatory T cells and enhances the efficacy of bleomycin in the treatment of mouse B16-F10 melanomas Journal article
Li, Ping, Chen, Fengyang, Zheng, Jingbin, Yang, Yang, Li, Yuan, Wang, Yifei, Chen, Xin*. Cyclophosphamide abrogates the expansion of CD4+Foxp3+ regulatory T cells and enhances the efficacy of bleomycin in the treatment of mouse B16-F10 melanomas[J]. Cancer Biology and Medicine, 2021, 18(4), 1010-1020.
Authors:  Li, Ping;  Chen, Fengyang;  Zheng, Jingbin;  Yang, Yang;  Li, Yuan; et al.
Favorite | TC[WOS]:8 TC[Scopus]:7  IF:5.6/5.9 | Submit date：2021/12/08
Bleomycin  Cyclophosphamide  Tnfr2  Tregs  Tumor Necrosis Factor  
Accumulation of TNFR2-expressing regulatory T cells in malignant pleural effusion of lung cancer patients is associated with poor prognosis Journal article
Ye, L., Peng, W., Niu, Y., Xiang, X., Wei, X., Wang, Z., Wang, X., Zhang, Z., Chen, X.*, Zhou, Q.. Accumulation of TNFR2-expressing regulatory T cells in malignant pleural effusion of lung cancer patients is associated with poor prognosis[J]. ANNALS OF TRANSLATIONAL MEDICINE, 2020, 1647-1647.
Authors:  Ye, L.;  Peng, W.;  Niu, Y.;  Xiang, X.;  Wei, X.; et al.
Favorite |  | Submit date：2022/08/30
Tumor Necrosis Factor Receptor Type 2 (Tnfr2)  Regulatory t Cells (Tregs)  Malignant Pleural Effusion (Mpe)