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Tetramethylpyrazine Nitrone Promotes the Clearance of Alpha-Synuclein via Nrf2-Mediated Ubiquitin–Proteasome System Activation Journal article
Guo, Baojian, Zheng, Chengyou, Cao, Jie, Qiu, Xiaoling, Luo, Fangcheng, Li, Haitao, Lee, Simon Mingyuan, Yang, Xifei, Zhang, Gaoxiao, Sun, Yewei, Zhang, Zaijun, Wang, Yuqiang. Tetramethylpyrazine Nitrone Promotes the Clearance of Alpha-Synuclein via Nrf2-Mediated Ubiquitin–Proteasome System Activation[J]. NeuroMolecular Medicine, 2024, 26(1), 9.
Authors:  Guo, Baojian;  Zheng, Chengyou;  Cao, Jie;  Qiu, Xiaoling;  Luo, Fangcheng; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:3.3/3.6 | Submit date：2024/05/16
Nuclear Factor Erythroid-2-related Factor 2  Parkinson’s Disease  Peroxisome Proliferator-activated Receptor γ Co-activator 1α  Tetramethylpyrazine Nitrone  Ubiquitin–proteasome System  Α-synuclein  
UBQLN2 and HSP70 participate in Parkin-mediated mitophagy by facilitating outer mitochondrial membrane rupture Journal article
Ma, Qilian, Xin, Jiaqi, Peng, Qiang, Li, Ningning, Sun, Shan, Hou, Hongyu, Ma, Guoqiang, Wang, Nana, Zhang, Li, Tam, Kin Yip, Dussmann, Heiko, Prehn, ochen Hm, Wang, Hongfeng, Ying, Zheng. UBQLN2 and HSP70 participate in Parkin-mediated mitophagy by facilitating outer mitochondrial membrane rupture[J]. EMBO Reports, 2023, 24(9), e55859.
Authors:  Ma, Qilian;  Xin, Jiaqi;  Peng, Qiang;  Li, Ningning;  Sun, Shan; et al.
Favorite | TC[WOS]:8 TC[Scopus]:7  IF:6.5/8.3 | Submit date：2023/08/22
Als  Mitophagy  Parkin  Ubiquitin  Ubqln2  
TRIM family proteins: roles in proteostasis and neurodegenerative diseases Review article
2022
Authors:  Zhu, Yan;  Afolabi, LO;  Wan, Xiaochun;  Shim, Joong Sup;  Chen, Liang
Favorite | TC[WOS]:18 TC[Scopus]:17  IF:4.5/5.9 | Submit date：2022/08/31
Neurodegenerative Diseases  Trim Proteins  Protein Aggregation  Proteostasis  Ubiquitin-proteasome System  Chaperone  
α-mangostin derivative 4e as a PDE4 inhibitor promote proteasomal degradation of alpha-synuclein in Parkinson's disease models through PKA activation Journal article
Chen, Jia Yue, Zhu, Qi, Cai, Cui Zan, Luo, Hai Bin, Lu, Jia Hong. α-mangostin derivative 4e as a PDE4 inhibitor promote proteasomal degradation of alpha-synuclein in Parkinson's disease models through PKA activation[J]. Phytomedicine, 2022, 101, 154125.
Authors:  Chen, Jia Yue;  Zhu, Qi;  Cai, Cui Zan;  Luo, Hai Bin;  Lu, Jia Hong
Favorite | TC[WOS]:8 TC[Scopus]:8  IF:6.7/6.2 | Submit date：2022/05/31
Alpha-synuclein (Α-syn)  Parkinson's Disease  Phosphodiesterase 4 Inhibitor  Protein Kinase a (Pka)  Ubiquitin-proteasome System (Ups)  
ANKRD13a controls early cell-death checkpoint by interacting with RIP1 independent of NF-κB Journal article
Won, Minho, Park, Kyeong Ah, Kim, Sup, Ju, Eunjin, Ko, Youngbok, Yoo, Heonjong, Ro, Hyunju, Lee, Jaeseob, Oh, Junseo, Lee, Eun Gyo, Kim, Sang Yean, Nam, Suk Woo, Shen, Han Ming, Yeo, Min Kyung, Kim, Jin Man, Hur, Gang Min. ANKRD13a controls early cell-death checkpoint by interacting with RIP1 independent of NF-κB[J]. Cell Death and Differentiation, 2022, 29(6), 1152-1163.
Authors:  Won, Minho;  Park, Kyeong Ah;  Kim, Sup;  Ju, Eunjin;  Ko, Youngbok; et al.
Favorite | TC[WOS]:5 TC[Scopus]:5  IF:13.7/13.7 | Submit date：2022/05/13
Tumor-necrosis-factor  Ubiquitin-binding  Tnf  Activation  Phosphorylation  Inflammation  Apoptosis  Protein  Cancer  Polyubiquitination  
USP13: Multiple functions and target Inhibition Journal article
Xiaolong Li, Ge Yang, Wenyao Zhang, Biying Qin, Zifan Ye, Huijing Shi, Xinmeng Zhao, Yihang Chen, Bowei Song, Ziqing Mei. USP13: Multiple functions and target Inhibition[J]. Frontiers in cell and developmental biology, 2022, 10, 875124.
Authors:  Xiaolong Li;  Ge Yang;  Wenyao Zhang;  Biying Qin;  Zifan Ye; et al.
Favorite | TC[WOS]:14 TC[Scopus]:13  IF:4.6/5.2 | Submit date：2023/08/28
Deubiquitination  Disease  Inhibitor  Structure  Ubiquitin-specific Protease 13  
USP13: Multiple Functions and Target Inhibition Journal article
Li, Xiaolong, Yang, Ge, Zhang, Wenyao, Qin, Biying, Ye, Zifan, Shi, Huijing, Zhao, Xinmeng, Chen, Yihang, Song, Bowei, Mei, Ziqing, Zhao, Qi, Wang, Feng. USP13: Multiple Functions and Target Inhibition[J]. Frontiers in Cell and Developmental Biology, 2022, 10, 875124.
Authors:  Li, Xiaolong;  Yang, Ge;  Zhang, Wenyao;  Qin, Biying;  Ye, Zifan; et al.
Favorite | TC[WOS]:14 TC[Scopus]:13  IF:4.6/5.2 | Submit date：2022/05/04
Deubiquitination  Disease  Inhibitor  Structure  Ubiquitin-specific Protease 13  
USP15 in Cancer and Other Diseases: From Diverse Functionsto Therapeutic Targets Review article
2022
Authors:  Li, Yan Chi;  Cai, Song Wang;  Shu, Yu Bin;  Chen, Mei Wan;  Shi, Zhi
Favorite | TC[WOS]:17 TC[Scopus]:17  IF:3.9/4.1 | Submit date：2022/03/04
Cancer  Deubiquitinatase  Target  Ubiquitin  Usp15  
Small molecules targeting ubiquitination to control inflammatory diseases Journal article
Zheng-Qing Li, Xiuping Chen, Ying Wang. Small molecules targeting ubiquitination to control inflammatory diseases[J]. DRUG DISCOVERY TODAY, 2021, 26(10), 2414-2422.
Authors:  Zheng-Qing Li;  Xiuping Chen;  Ying Wang
Favorite | TC[WOS]:5 TC[Scopus]:4  IF:6.5/7.3 | Submit date：2021/12/08
Ubiquitin  Ubiquitination System  Inflammatory Diseases  Small Molecule Modulator  
Lycorine, a natural alkaloid, promotes the degradation of alpha-synuclein via PKA-mediated UPS activation in transgenic Parkinson's disease models Journal article
Zhu, Qi, Zhuang, Xu xu, Chen, Jia yue, Yuan, Ning ning, Chen, Yan, Cai, Cui zan, Tan, Jie qiong, Su, Huan xing, Lu, Jia hong. Lycorine, a natural alkaloid, promotes the degradation of alpha-synuclein via PKA-mediated UPS activation in transgenic Parkinson's disease models[J]. Phytomedicine, 2021, 87, 153578.
Authors:  Zhu, Qi;  Zhuang, Xu xu;  Chen, Jia yue;  Yuan, Ning ning;  Chen, Yan; et al.
Favorite | TC[WOS]:17 TC[Scopus]:18  IF:6.7/6.2 | Submit date：2021/12/08
Camp/pka Pathway  Lycorine  Parkinson's Disease  Ubiquitin-proteasome System  Α-synuclein