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Non-apoptotic cell death-based cancer therapy: Molecular mechanism, pharmacological modulators, and nanomedicine Journal article
Wang, Xuan, Hua, Peng, He, Chengwei, Chen, Meiwan. Non-apoptotic cell death-based cancer therapy: Molecular mechanism, pharmacological modulators, and nanomedicine[J]. Acta Pharmaceutica Sinica B, 2022, 12(9), 3567-3593.
Authors:  Wang, Xuan;  Hua, Peng;  He, Chengwei;  Chen, Meiwan
Favorite | TC[WOS]:58 TC[Scopus]:65  IF:14.7/14.1 | Submit date：2022/05/17
Anticancer  Autophagy  Combination Therapies  Ferroptosis  Nanomedicine  Necroptosis  Non-apoptotic Cell Death  Pyroptosis  
3-O-acetylrubianol C (3AR-C) induces RIPK1-dependent programmed cell death by selective inhibition of IKKβ Journal article
Kang,Kidong, Quan,Khong Trong, Byun,Hee Sun, Lee,So Ra, Piao,Xuezhe, Ju,Eunjin, Park,Kyeong Ah, Sohn,Kyung Cheol, Shen,Han Ming, Na,Min Kyun, Hur,Gang Min. 3-O-acetylrubianol C (3AR-C) induces RIPK1-dependent programmed cell death by selective inhibition of IKKβ[J]. FASEB Journal, 2020, 34(3), 4369-4383.
Authors:  Kang,Kidong;  Quan,Khong Trong;  Byun,Hee Sun;  Lee,So Ra;  Piao,Xuezhe; et al.
Favorite | TC[WOS]:6 TC[Scopus]:5  IF:4.4/4.7 | Submit date：2021/03/02
3ar-c  Apoptosis  Ikkβ  Necroptosis  Phosphorylation  Ripk1  Tnf  
An NQO1 dependent ROS and RIP1/RIP3 mediated necroptosis induced in glioma cancer cells by MAM Conference paper
Yu, J., Wu, X.X., Wang, C.X., Sun, W., Hou, Y., Zhang, Y.Y., Li, Z.W., Lu, J., Chen, X. P.. An NQO1 dependent ROS and RIP1/RIP3 mediated necroptosis induced in glioma cancer cells by MAM[C], 2018.
Authors:  Yu, J.;  Wu, X.X.;  Wang, C.X.;  Sun, W.;  Hou, Y.; et al.
Favorite |  | Submit date：2022/08/26
MAM  necroptosis  glioma  
NQO1 dependent non-canonical necroptosis mediated by ROS and RIP1/RIP3 in parallel in glioma cancer cells Conference paper
Yu, J., Wu, X.X., Wang, C.X., Gao, H.W., Sun, W., Lu, J., Chen, X. P.. NQO1 dependent non-canonical necroptosis mediated by ROS and RIP1/RIP3 in parallel in glioma cancer cells[C], 2018.
Authors:  Yu, J.;  Wu, X.X.;  Wang, C.X.;  Gao, H.W.;  Sun, W.; et al.
Favorite |  | Submit date：2022/08/26
MAM  glioblastomas  non-canonical necroptosis  NQO1  
Dihydrotanshinone I, a natural product, ameliorates DSS-induced experimental ulcerative colitis in mice Journal article
Guo, Yanling, Wu, Xiaxia, Wu, Qin, Lu, Yuanfu, Shi, Jingshan, Chen, Xiuping. Dihydrotanshinone I, a natural product, ameliorates DSS-induced experimental ulcerative colitis in mice[J]. TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018, 344, 35-45.
Authors:  Guo, Yanling;  Wu, Xiaxia;  Wu, Qin;  Lu, Yuanfu;  Shi, Jingshan; et al.
Favorite | TC[WOS]:49 TC[Scopus]:53  IF:3.3/3.6 | Submit date：2018/10/30
15,16-dihydrotanshinone i  Ulcerative Colitis  Inflammation  Necroptosis  
An NQO1 dependent ROS and RIP1/RIP3 mediated necroptosis induced in glioma cancer cells by a natural product, 2-Methoxy-6-acetyl-7-methyljuglone (MAM) Conference paper
Yu, J., Li, Z.W., Hou, Y., Yuan, R.Y.K., Lu, J., Chen, X. P.. An NQO1 dependent ROS and RIP1/RIP3 mediated necroptosis induced in glioma cancer cells by a natural product, 2-Methoxy-6-acetyl-7-methyljuglone (MAM)[C], 2017.
Authors:  Yu, J.;  Li, Z.W.;  Hou, Y.;  Yuan, R.Y.K.;  Lu, J.; et al.
Favorite |  | Submit date：2022/08/26
MAM  necroptosis  NQO1  ROS  RIP1/RIP3  
Cytosolic calcium mediates RIP1/RIP3 complex-dependent necroptosis through JNK activation and mitochondrial ROS production in human colon cancer cells. Journal article
Sun, W, Wu, XX, Gao, HW, Yu, J, Zhao, WW, Lu, J., Wang, JH, Du, GH, Chen, X. P.. Cytosolic calcium mediates RIP1/RIP3 complex-dependent necroptosis through JNK activation and mitochondrial ROS production in human colon cancer cells.[J]. Free Radical Biology & Medicine, 2017, 433-444.
Authors:  Sun, W;  Wu, XX;  Gao, HW;  Yu, J;  Zhao, WW; et al.
Favorite |   IF:7.1/7.9 | Submit date：2022/03/31
Necroptosis  C-jun N-terminal Kinase  Calcium  
Cytosolic calcium mediates RIP1/RIP3 complex-dependent necroptosis through JNK activation and mitochondrial ROS production in human colon cancer cells Journal article
Sun, Wen, Wu, Xiaxia, Gao, Hongwei, Yu, Jie, Zhao, Wenwen, Lu, Jin-Jian, Wang, Jinhua, Du, Guanhua, Chen, Xiuping. Cytosolic calcium mediates RIP1/RIP3 complex-dependent necroptosis through JNK activation and mitochondrial ROS production in human colon cancer cells[J]. FREE RADICAL BIOLOGY AND MEDICINE, 2017, 108, 433-444.
Authors:  Sun, Wen;  Wu, Xiaxia;  Gao, Hongwei;  Yu, Jie;  Zhao, Wenwen; et al.
Favorite | TC[WOS]:112 TC[Scopus]:116  IF:7.1/7.9 | Submit date：2018/10/30
Necroptosis  Cell Death  Ros  Calcium  
Tert-butyl hydroperoxide (t-BHP) induced apoptosis and necroptosis in endothelial cells: Roles of NOX4 and mitochondrion Journal article
Zhao, Wenwen, Feng, Haitao, Sun, Wen, Liu, Kang, Lu, Jin-Jian, Chen, Xiuping. Tert-butyl hydroperoxide (t-BHP) induced apoptosis and necroptosis in endothelial cells: Roles of NOX4 and mitochondrion[J]. REDOX BIOLOGY, 2017, 11, 524-534.
Authors:  Zhao, Wenwen;  Feng, Haitao;  Sun, Wen;  Liu, Kang;  Lu, Jin-Jian; et al.
Favorite | TC[WOS]:94 TC[Scopus]:95  IF:10.7/11.7 | Submit date：2018/10/30
Apoptosis  Necroptosis  Reactive Oxygen Species  Nox4  Mitochondria  Endothelial Cells  
2-Methoxy-6-acetyl-7-methyljuglone (MAM), a natural naphthoquinone, induces NO-dependent apoptosis and necroptosis by H2O2-dependent JNK activation in cancer cells. Journal article
Sun, W, Bao, JL, Lin, W, Gao, HW, Zhao, WW, Zhang, Q. W., Leung, C. H., Ma, DL, Lu, J., Chen, X. P.. 2-Methoxy-6-acetyl-7-methyljuglone (MAM), a natural naphthoquinone, induces NO-dependent apoptosis and necroptosis by H2O2-dependent JNK activation in cancer cells.[J]. Free Radical Biology & Medicine, 2016, 61-77.
Authors:  Sun, W;  Bao, JL;  Lin, W;  Gao, HW;  Zhao, WW; et al.
Favorite |   IF:7.1/7.9 | Submit date：2022/03/31
Apoptosis  Cancer  Mam  No  Necroptosis  Ros