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Ginsenoside Rh2 augmented anti-PD-L1 immunotherapy by reinvigorating CD8+ T cells via increasing intratumoral CXCL10 Journal article
Huang, Mu Yang, Chen, Yu Chi, Lyu, Wen Yu, He, Xin Yu, Ye, Zi Han, Huang, Can Yu, He, Xin Ling, Chen, Xiuping, Chen, Xiaobing, Zhang, Baoxian, Kai, Guoyin, Zhang, Xiaolei, Li, Ting, Huang, Mingqing, Lu, Jin Jian. Ginsenoside Rh2 augmented anti-PD-L1 immunotherapy by reinvigorating CD8+ T cells via increasing intratumoral CXCL10[J]. Pharmacological Research, 2023, 198, 106988.
Authors:  Huang, Mu Yang;  Chen, Yu Chi;  Lyu, Wen Yu;  He, Xin Yu;  Ye, Zi Han; et al.
Favorite | TC[WOS]:11 TC[Scopus]:14  IF:9.1/9.0 | Submit date：2024/01/02
Combination Treatment  Ginsenoside Rh2  Pd-1/pd-l1  t Cells  Tumor Microenvironment  
Aberrant frequency of TNFR2-expressing CD4+ FoxP3+ regulatory T cells in nasopharyngeal carcinoma patients Journal article
Engku Nur Syafirah Engku Abd Rahman, Ahmad Adebayo Irekeola, Rafidah Hanim Shueb, Norhafiza Mat Lazim, Rohimah Mohamud, Xin Chen, Liyana Ghazali, Nik Mohd Syahrul Hafizzi Awang, Ali Haron, Yean Yean Chan. Aberrant frequency of TNFR2-expressing CD4+ FoxP3+ regulatory T cells in nasopharyngeal carcinoma patients[J]. Cytokine, 2023, 170, 156341.
Authors:  Engku Nur Syafirah Engku Abd Rahman;  Ahmad Adebayo Irekeola;  Rafidah Hanim Shueb;  Norhafiza Mat Lazim;  Rohimah Mohamud; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:3.7/3.5 | Submit date：2023/09/22
Nasopharyngeal Carcinoma  Regulatory t Cells  Tnfr2  Tumour Microenvironment  
Editorial: The role of TNF-TNFR2 signal in immunosuppressive cells and its therapeutic implications, volume II Journal article
XIN CHEN, Magdalena Plebanski. Editorial: The role of TNF-TNFR2 signal in immunosuppressive cells and its therapeutic implications, volume II[J]. Frontiers in Immunology, 2023, 14, 1227003.
Authors:  XIN CHEN;  Magdalena Plebanski
Favorite | TC[WOS]:1 TC[Scopus]:0  IF:5.7/6.8 | Submit date：2023/08/31
Tnf  Tnfr2  Cd4++ Foxp3++ Regulatory t Cells  Inflammation  Cancer  Autoimmune Diseases  
Rubiginosin B selectively inhibits Treg cell differentiation and enhances anti-tumor immune responses by targeting calcineurin-NFAT signaling pathway Journal article
Geng,Chang An, Chen,Feng Yang, Zheng,Jing Bin, Liao,Ping, Li,Tian Ze, Zhang,Xue Mei, Chen,Xin*, Chen,Ji Jun. Rubiginosin B selectively inhibits Treg cell differentiation and enhances anti-tumor immune responses by targeting calcineurin-NFAT signaling pathway[J]. Phytomedicine, 2023, 116, 154898.
Authors:  Geng,Chang An;  Chen,Feng Yang;  Zheng,Jing Bin;  Liao,Ping;  Li,Tian Ze; et al.
Favorite | TC[WOS]:3 TC[Scopus]:3  IF:6.7/6.2 | Submit date：2023/08/03
Calcineurin  cd4+foxp3+ Regulatory t Cells (Tregs)  Nuclear Factor Of Activated t Cells (Nfat)  Rhododendron Brachypodum  Rubiginosin b (Rgb)  Tumor Microenvironment  
Anti-TNFR2 enhanced the antitumor activity of a new HMGN1/3M-052 stimulated dendritic cell vaccine in a mouse model of colon cancer Journal article
Zhu, Lan, Zhang, Xiangyan, Chen, Xin, Yang, De, Nie, Yujie, Pan, Runsang, Li, Linzhao, Wang, Chenglv, Gui, Huan, Chen, Shuanghui, Jing, Qianyu, Wang, Mengjiao, Nie, Yingjie. Anti-TNFR2 enhanced the antitumor activity of a new HMGN1/3M-052 stimulated dendritic cell vaccine in a mouse model of colon cancer[J]. Biochemical and Biophysical Research Communications, 2023, 653, 106-114.
Authors:  Zhu, Lan;  Zhang, Xiangyan;  Chen, Xin;  Yang, De;  Nie, Yujie; et al.
Favorite | TC[WOS]:6 TC[Scopus]:5  IF:2.5/2.7 | Submit date：2023/05/02
Anti-tnfr2  Antitumor  cd4+foxp3+regulatory t Cells (Tregs)  Dendritic Cells (Dcs)  Hmgn1 And 3m-052  Immunotherapy  
Exosome-Modified Liposomes Targeted Delivery of Thalidomide to Regulate Treg Cells for Antitumor Immunotherapy Journal article
Yang,Yang, Wang,Qingfu, Zou,Huimin, Chou Chon-Kit, Chen Xin*. Exosome-Modified Liposomes Targeted Delivery of Thalidomide to Regulate Treg Cells for Antitumor Immunotherapy[J]. Pharmaceutics, 2023, 15(4), 1074.
Authors:  Yang,Yang;  Wang,Qingfu;  Zou,Huimin;  Chou Chon-Kit;  Chen Xin*
Favorite | TC[WOS]:5 TC[Scopus]:5  IF:4.9/5.5 | Submit date：2023/08/03
Exosome  Regulatory t Cells (Tregs)  Thalidomide  Tnfr2  
TNFR2 expression predicts the responses to immune checkpoint inhibitor treatments Journal article
Ping Liao, Mengmeng Jiang, Md Sahidul Islam, Yiru Wang, XIN CHEN*. TNFR2 expression predicts the responses to immune checkpoint inhibitor treatments[J]. Frontiers in Immunology, 2023, 14, 1097090.
Authors:  Ping Liao;  Mengmeng Jiang;  Md Sahidul Islam;  Yiru Wang;  XIN CHEN*
Favorite | TC[WOS]:5 TC[Scopus]:5  IF:5.7/6.8 | Submit date：2023/08/31
Tnfr2  Immune Checkpoint Inhibitors  Tumor Microenvironment  Cd4 + Foxp3 + Regulatory t Cells  Exhausted Cd8 t Cells  Biomarker  
Self-Degradable Nanogels Reshape Immunosuppressive Tumor Microenvironment via Drug Repurposing Strategy to Reactivate Cytotoxic CD8+ T Cells Journal article
Tian,Hao, Li,Wenxi, Wang,Guohao, Tian,Ye, Yan,Jie, Zhou,Songtao, Yu,Xinying, Li,Bei, Dai,Yunlu. Self-Degradable Nanogels Reshape Immunosuppressive Tumor Microenvironment via Drug Repurposing Strategy to Reactivate Cytotoxic CD8+ T Cells[J]. Advanced Science, 2023, 10(21).
Authors:  Tian,Hao;  Li,Wenxi;  Wang,Guohao;  Tian,Ye;  Yan,Jie; et al.
Favorite | TC[WOS]:6 TC[Scopus]:11  IF:14.3/16.3 | Submit date：2023/08/03
Cd8++++ t Cells  Drug Repurposing  Immunosuppressive Tumor Microenvironment  Self-degradable Nanogels  
Scutellarin enhances anti-tumor immune responses by reducing TNFR2-expressing CD4+Foxp3+ regulatory T cells Journal article
Chen, Shaokui, Li, Ruixin, Chen, Yibo, Chou, Chon Kit, Zhang, Zhexuan, Yang, Yang, Liao, Ping, Wang, Qingqing, Chen, Xin*. Scutellarin enhances anti-tumor immune responses by reducing TNFR2-expressing CD4+Foxp3+ regulatory T cells[J]. Biomedicine and Pharmacotherapy, 2022, 151, 113187.
Authors:  Chen, Shaokui;  Li, Ruixin;  Chen, Yibo;  Chou, Chon Kit;  Zhang, Zhexuan; et al.
Favorite | TC[WOS]:10 TC[Scopus]:12  IF:6.9/6.8 | Submit date：2022/08/02
Cancer Immunotherapy  cd4+foxp3+ Regulatory t Cells  Cpg Oligodeoxynucleotide  Scutellarin  Tumor Necrosis Factor  Tumor Necrosis Factor Receptor Ii  
Topical Application of Tetrandrine Nanoemulsion Promotes the Expansion of CD4+Foxp3+ Regulatory T Cells and Alleviates Imiquimod-Induced Psoriasis in Mice Journal article
Chen, Shaokui, Lin, Zibei, He, Tianzhen, Islam, Md Sahidul, Xi, Long, Liao, Ping, Yang, Yang, Zheng, Ying, Chen, Xin*. Topical Application of Tetrandrine Nanoemulsion Promotes the Expansion of CD4+Foxp3+ Regulatory T Cells and Alleviates Imiquimod-Induced Psoriasis in Mice[J]. Frontiers in Immunology, 2022, 13, 800283.
Authors:  Chen, Shaokui;  Lin, Zibei;  He, Tianzhen;  Islam, Md Sahidul;  Xi, Long; et al.
Favorite | TC[WOS]:5 TC[Scopus]:7  IF:5.7/6.8 | Submit date：2022/05/04
cd4+foxp3+ Regulatory t Cells  Nanoemulsion  Psoriasis  Tetrandrine  Th17 cells  Tnfr2