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Development of small molecule inhibitors targeting RNA helicase DHX33 as anti-cancer agents Journal article
Wang, Yingcai, Nie, Guangli, Wang, Xingshun, Ge, Wei, Zhang, Yandong. Development of small molecule inhibitors targeting RNA helicase DHX33 as anti-cancer agents[J]. Bioorganic and Medicinal Chemistry Letters, 2023, 96, 129505.
Authors:  Wang, Yingcai;  Nie, Guangli;  Wang, Xingshun;  Ge, Wei;  Zhang, Yandong
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:2.5/2.4 | Submit date：2023/12/04
Cancer  Dhx33  Rna Helicase  Inhibitor High Throughput Screening (Hts)  
Discovery of honokiol thioethers containing 1,3,4-oxadiazole moieties as potential α-glucosidase and SARS-CoV-2 entry inhibitors Journal article
Xu, Ting, Meng, Jie Ru, Cheng, Wanqing, Liu, Jia Zheng, Chu, Junyan, Zhang, Qian, Ma, Nannan, Bai, Li Ping, Guo, Yong. Discovery of honokiol thioethers containing 1,3,4-oxadiazole moieties as potential α-glucosidase and SARS-CoV-2 entry inhibitors[J]. Bioorganic and Medicinal Chemistry, 2022, 67.
Authors:  Xu, Ting;  Meng, Jie Ru;  Cheng, Wanqing;  Liu, Jia Zheng;  Chu, Junyan; et al.
Favorite | TC[WOS]:10 TC[Scopus]:10  IF:3.3/3.1 | Submit date：2023/01/30
1,3,4-oxadiazole  Honokiol  Sars-cov-2 Entry Inhibitor  Thioethers  Α-glucosidase Inhibitor  
Andrographolide derivative as antagonist of vitamin D receptor to induce lipidation of microtubule associate protein 1 light chain 3 (LC3) Journal article
Ding, Mo Yu, Peng, Yuran, Li, Feng, Li, Zheng Qing, Wang, Decai, Zhou, Guo Chun, Wang, Ying. Andrographolide derivative as antagonist of vitamin D receptor to induce lipidation of microtubule associate protein 1 light chain 3 (LC3)[J]. Bioorganic and Medicinal Chemistry, 2021, 51, 116505.
Authors:  Ding, Mo Yu;  Peng, Yuran;  Li, Feng;  Li, Zheng Qing;  Wang, Decai; et al.
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:3.3/3.1 | Submit date：2021/12/08
Andrographolide Derivative  Lipidation  Microtubule Associated Protein 1 Light Chain 3  Parkinsonism  Vitamin d Receptor  
Andrographolide derivative as antagonist of vitamin D receptor to induce lipidation of microtubule associate protein 1 light chain 3 (LC3) Journal article
Moyu Ding, Yuran Peng, Feng Li, Zhengqing Li, Decai Wang, Guo-Chun Zhou, Wang Y(王穎). Andrographolide derivative as antagonist of vitamin D receptor to induce lipidation of microtubule associate protein 1 light chain 3 (LC3)[J]. Bioorganic & Medicinal Chemistry, 2021, 51, 116505.
Authors:  Moyu Ding;  Yuran Peng;  Feng Li;  Zhengqing Li;  Decai Wang; et al.
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:3.3/3.1 | Submit date：2023/07/07
Synthesis and biological effect of lysosome-targeting fluorescent anion transporters with enhanced anionophoric activity Journal article
Hong,Xiao Qiao, He,Xiang Yu, Tam,Kin Yip, Chen,Wen Hua. Synthesis and biological effect of lysosome-targeting fluorescent anion transporters with enhanced anionophoric activity[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 30(19), 127461.
Authors:  Hong,Xiao Qiao;  He,Xiang Yu;  Tam,Kin Yip;  Chen,Wen Hua
Favorite | TC[WOS]:7 TC[Scopus]:7  IF:2.5/2.4 | Submit date：2021/03/04
Fluorescent Anion Transporter  Lysosome Targeting  Lysosomal Alkalization  Cathepsin b Enzyme  
Discovery of fused bicyclic derivatives of 1H-pyrrolo[1,2-c]imidazol-1-one as VDR signaling regulators Journal article
Bin Xu, Mo-Yu Ding, Zhibing Weng, Zheng-Qing Li, Feng Li, Xia Sun, Qiu-Ling Chen, Yi-Tao Wang, Ying Wang, Guo-Chun Zhou. Discovery of fused bicyclic derivatives of 1H-pyrrolo[1,2-c]imidazol-1-one as VDR signaling regulators[J]. BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 27(17), 3879-3888.
Authors:  Bin Xu;  Mo-Yu Ding;  Zhibing Weng;  Zheng-Qing Li;  Feng Li; et al.
Adobe PDF | Favorite | TC[WOS]:8 TC[Scopus]:8  IF:3.3/3.1 | Submit date：2019/11/22
1h-pyrrolo[1,2-c]Imidazol-1-one  Vitamin d Receptor (Vdr)  Autophagy  Apoptosis  
Dichloroacetophenones targeting at pyruvate dehydrogenase kinase 1 with improved selectivity and antiproliferative activity: Synthesis and structure-activity relationships Journal article
Zhang,Shao Lin, Yang,Zheng, Hu,Xiaohui, Tam,Kin Yip. Dichloroacetophenones targeting at pyruvate dehydrogenase kinase 1 with improved selectivity and antiproliferative activity: Synthesis and structure-activity relationships[J]. Bioorganic and Medicinal Chemistry Letters, 2018, 28(21), 3441-3445.
Authors:  Zhang,Shao Lin;  Yang,Zheng;  Hu,Xiaohui;  Tam,Kin Yip
Favorite | TC[WOS]:16 TC[Scopus]:16  IF:2.5/2.4 | Submit date：2021/03/04
Antiproliferative Activity  Dichloroacetophenone  Kinase Inhibition  Pyruvate Dehydrogenase Complex  Pyruvate Dehydrogenase Kinase  
Dichloroacetophenones targeting at pyruvate dehydrogenase kinase 1 with improved selectivity and antiproliferative activity: Synthesis and structure-activity relationships Journal article
Zhang, Shao-Lin, Yang, Zheng, Hu, Xiaohui, Tam, Kin Yip. Dichloroacetophenones targeting at pyruvate dehydrogenase kinase 1 with improved selectivity and antiproliferative activity: Synthesis and structure-activity relationships[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 28(21), 3441-3445.
Authors:  Zhang, Shao-Lin;  Yang, Zheng;  Hu, Xiaohui;  Tam, Kin Yip
Favorite | TC[WOS]:16 TC[Scopus]:16  IF:2.5/2.4 | Submit date：2018/10/30
Pyruvate Dehydrogenase Kinase  Pyruvate Dehydrogenase Complex  Antiproliferative Activity  Dichloroacetophenone  Kinase Inhibition  
Andrographolide Derivative as STAT3 Inhibitor to Treat Acute Liver Damage in Mice Journal article
Chen, S.R., Li, F, Ding, M.Y., Wang, D, Zhao, Q., Wang, Y. T., Zhou, G.C., Wang, Y.. Andrographolide Derivative as STAT3 Inhibitor to Treat Acute Liver Damage in Mice[J]. Bioorganic & Medicinal Chemistry, 2018, 5053-5061.
Authors:  Chen, S.R.;  Li, F;  Ding, M.Y.;  Wang, D;  Zhao, Q.; et al.
Favorite |   IF:3.3/3.1 | Submit date：2023/08/30
andrographolide  STAT3  acute liver damage.  
Andrographolide derivative as STAT3 inhibitor that protects acute liver damage in mice Journal article
Chen, Shao-Ru, Li, Feng, Ding, Mo-Yu, Wang, Decai, Zhao, Qi, Wang, Yitao, Zhou, Guo-Chun, Wang, Ying. Andrographolide derivative as STAT3 inhibitor that protects acute liver damage in mice[J]. BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 26(18), 5053-5061.
Authors:  Chen, Shao-Ru;  Li, Feng;  Ding, Mo-Yu;  Wang, Decai;  Zhao, Qi; et al.
View | Adobe PDF | Favorite | TC[WOS]:15 TC[Scopus]:16  IF:3.3/3.1 | Submit date：2018/10/30
Andrographolide  Stat3 Inhibitor  Acute Liver Damage  Inflammation