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Mitochondrial complex I inhibition by homoharringtonine: A novel strategy for suppression of chronic myeloid leukemia Journal article
Han, Han, Zhao, Chen, Liu, Mengchen, Zhu, Hongxuan, Meng, Fancheng, Zhang, Ying, Wang, Guibin, Wang, Li, Di, Lijun, Mingyuen Lee, Simon, Zhang, Qingwen, Cui, Guozhen. Mitochondrial complex I inhibition by homoharringtonine: A novel strategy for suppression of chronic myeloid leukemia[J]. Biochemical Pharmacology, 2023, 218, 115875.
Authors:  Han, Han;  Zhao, Chen;  Liu, Mengchen;  Zhu, Hongxuan;  Meng, Fancheng; et al.
Favorite | TC[WOS]:3 TC[Scopus]:3  IF:5.3/5.2 | Submit date：2024/01/02
Chronic Myeloid Leukemia  Homoharringtonine  Mitochondrial Complex i  Oxidative Phosphorylation  Proteomics  T315i Mutation  
Nitrovin (difurazone), an antibacterial growth promoter, induces ROS-mediated paraptosis-like cell death by targeting thioredoxin reductase 1 (TrxR1) Journal article
Zhao, Lin, Zhong, Bingling, Zhu, Yanyan, Zheng, Haoyi, Wang, Xumei, Hou, Ying, Lu, Jin Jian, Ai, Nana, Guo, Xiuli, Ge, Wei, Ma, Yan Yan, Chen, Xiuping. Nitrovin (difurazone), an antibacterial growth promoter, induces ROS-mediated paraptosis-like cell death by targeting thioredoxin reductase 1 (TrxR1)[J]. Biochemical Pharmacology, 2023, 210, 115487.
Authors:  Zhao, Lin;  Zhong, Bingling;  Zhu, Yanyan;  Zheng, Haoyi;  Wang, Xumei; et al.
Favorite | TC[WOS]:10 TC[Scopus]:10  IF:5.3/5.2 | Submit date：2023/05/02
Nitrovin  Paraptosis  Trxr1  Ros  Glioblastoma  
Myricetin inhibits interferon-γ-induced PD-L1 and IDO1 expression in lung cancer cells Journal article
Chen, Yu Chi, He, Xin Ling, Qi, Lu, Shi, Wei, Yuan, Luo Wei, Huang, Mu Yang, Xu, Yu Lian, Chen, Xiuping, Gu, Lei, Zhang, Le Le, Lu, Jin Jian. Myricetin inhibits interferon-γ-induced PD-L1 and IDO1 expression in lung cancer cells[J]. Biochemical Pharmacology, 2022, 197, 114940.
Authors:  Chen, Yu Chi;  He, Xin Ling;  Qi, Lu;  Shi, Wei;  Yuan, Luo Wei; et al.
Favorite | TC[WOS]:20 TC[Scopus]:22  IF:5.3/5.2 | Submit date：2022/03/28
Indoleamine 2, 3-dioxygenase 1  Interferon-γ  Lung Cancer  Myricetin  Programmed Death Ligand-1  
Glytabastan B, a coumestan isolated from Glycine tabacina, alleviated synovial inflammation, osteoclastogenesis and collagen-induced arthritis through inhibiting MAPK and PI3K/AKT pathways Journal article
Tu, Yanbei, Tan, Lihua, Lu, Tao, Wang, Kai, Wang, Haiyong, Han, Bing, Zhao, Yuxin, Chen, Hanbin, Li, Yanfang, Chen, Haixia, Chen, Meiwan, He, Chengwei. Glytabastan B, a coumestan isolated from Glycine tabacina, alleviated synovial inflammation, osteoclastogenesis and collagen-induced arthritis through inhibiting MAPK and PI3K/AKT pathways[J]. Biochemical Pharmacology, 2022, 197, 114912.
Authors:  Tu, Yanbei;  Tan, Lihua;  Lu, Tao;  Wang, Kai;  Wang, Haiyong; et al.
Favorite | TC[WOS]:12 TC[Scopus]:15  IF:5.3/5.2 | Submit date：2022/03/28
Glycine Tabacina  Glytabastan b  Inflammation  Network Pharmacology  Osteoclast  Rheumatoid Arthritis  
Development and application of novel electrophilic warheads in target identification and drug discovery Review article
2021
Authors:  Liu, Yue;  Lv, Shumin;  Peng, Lijie;  Xie, Chengliang;  Gao, Liqian; et al.
Favorite | TC[WOS]:21 TC[Scopus]:22  IF:5.3/5.2 | Submit date：2021/12/08
Activity-based Protein Profiling  Amino Acid Residues  Covalent Inhibitors  Electrophilic Warhead  Protein Target  
Human gut bacterial β-glucuronidase inhibition: An emerging approach to manage medication therapy Journal article
Wang, Panpan, Jia, Yifei, Wu, Rongrong, Chen, Zhiqiang, Yan, Ru. Human gut bacterial β-glucuronidase inhibition: An emerging approach to manage medication therapy[J]. Biochemical Pharmacology, 2021, 190, 114566.
Authors:  Wang, Panpan;  Jia, Yifei;  Wu, Rongrong;  Chen, Zhiqiang;  Yan, Ru
Favorite | TC[WOS]:30 TC[Scopus]:41  IF:5.3/5.2 | Submit date：2021/12/08
Β-glucuronidases  Gut Microbial Metabolism  Drug Toxicity  Gus Inhibitor  Gut Microbiota  
Clonazepam attenuates neurobehavioral abnormalities in offspring exposed to maternal immune activation by enhancing GABAergic neurotransmission Journal article
Yang, Youjun, Wang, Baojia, Zhong, Zhanqion, Chen, Hanbin, Ding, Weijun, Hoi, Maggie Pui Man. Clonazepam attenuates neurobehavioral abnormalities in offspring exposed to maternal immune activation by enhancing GABAergic neurotransmission[J]. BIOCHEMICAL PHARMACOLOGY, 2021, 192, 114711.
Authors:  Yang, Youjun;  Wang, Baojia;  Zhong, Zhanqion;  Chen, Hanbin;  Ding, Weijun; et al.
Favorite | TC[WOS]:10 TC[Scopus]:11  IF:5.3/5.2 | Submit date：2021/12/08
Maternal Immune Activation  Gabaergic Neurotransmission  Clonazepam  Neurobehavioral Abnormalities  Prefrontal Cortex  
Human Gut Microbial β-Glucuronidase Inhibition: An Emerging Approach to Manage Medication Therapy Journal article
Wang, Panpan, Jia, Yifei, Wu, Rongrong, Chen, Zhiqiang, YAN RU. Human Gut Microbial β-Glucuronidase Inhibition: An Emerging Approach to Manage Medication Therapy[J]. Biochemical Pharmacology, 2021, 190, 114566.
Authors:  Wang, Panpan;  Jia, Yifei;  Wu, Rongrong;  Chen, Zhiqiang;  YAN RU
Favorite |   IF:5.3/5.2 | Submit date：2023/08/31
Gut Microbiota  Gut Microbial Β-glucuronidases  Inhibition  Medication Therapy  
β-patchoulene simultaneously ameliorated dextran sulfate sodium-induced colitis and secondary liver injury in mice via suppressing colonic leakage and flora imbalance Journal article
Liu, Yuhong, Wu, Jiazhen, Chen, Liping, Wu, Xue, Gan, Yuxuan, Xu, Nan, Li, Minyao, Luo, Huijuan, Guan, Fengkun, Su, Ziren, Chen, Jiannan, Li, Yucui. β-patchoulene simultaneously ameliorated dextran sulfate sodium-induced colitis and secondary liver injury in mice via suppressing colonic leakage and flora imbalance[J]. Biochemical Pharmacology, 2020, 182, 114260.
Authors:  Liu, Yuhong;  Wu, Jiazhen;  Chen, Liping;  Wu, Xue;  Gan, Yuxuan; et al.
Favorite | TC[WOS]:22 TC[Scopus]:23  IF:5.3/5.2 | Submit date：2021/12/06
Colitis  Colonic Leakage  Flora Imbalance  Secondary Liver Injury  Β-patchoulene  
Activation of notch 3/c-MYC/CHOP axis regulates apoptosis and promotes sensitivity of lung cancer cells to mTOR inhibitor everolimus Journal article
Li,Ting, Xu,Xiao Huang, Guo,Xia, Yuan,Tao, Tang,Zheng Hai, Jiang,Xiao Ming, Xu,Yu Lian, Zhang,Le Le, Chen,Xiuping, Zhu,Hong, Shi,Jia Jie, Lu,Jin Jian. Activation of notch 3/c-MYC/CHOP axis regulates apoptosis and promotes sensitivity of lung cancer cells to mTOR inhibitor everolimus[J]. Biochemical Pharmacology, 2020, 175.
Authors:  Li,Ting;  Xu,Xiao Huang;  Guo,Xia;  Yuan,Tao;  Tang,Zheng Hai; et al.
Favorite | TC[WOS]:17 TC[Scopus]:19  IF:5.3/5.2 | Submit date：2021/03/01
Lung Cancer  Notch 3  C-myc  Chop  Apoptosis