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Ubiquitin-Specific Proteases: Key Regulators in TLR/IL-1R Signaling and Inflammatory Disease Progression (Major revision) Journal article
Chon-kit Chou*, Yiru Wang, Brenda Kischkel, Xin Chen and Leo A.B. Joosten*. Ubiquitin-Specific Proteases: Key Regulators in TLR/IL-1R Signaling and Inflammatory Disease Progression (Major revision)[J]. Cell Communication and Signaling, 2025.
Authors:  Chon-kit Chou*, Yiru Wang, Brenda Kischkel, Xin Chen and Leo A.B. Joosten*
Favorite |   IF:8.2/8.0 | Submit date：2025/01/17
Anti-TNF therapy in the treatment of systemic autoinflammatory diseases: the responses of innate immune cells Journal article
Shuyi Wang, Rufei Xiao, Yibo Chen, Yishan Ye, Tianzhen He, Yang Yang, Xin Chen, Chon-Kit Chou. Anti-TNF therapy in the treatment of systemic autoinflammatory diseases: the responses of innate immune cells[J]. Journal of Leukocyte Biology, 2025.
Authors:  Shuyi Wang;  Rufei Xiao;  Yibo Chen;  Yishan Ye;  Tianzhen He; et al.
Favorite |   IF:3.6/5.2 | Submit date：2025/01/17
Keywords: Systemic Autoinflammatory Diseases  Anti-tnf Therapy  Innate Immune Cells  Autoinflammation  Tnf Inhibitors: Tnfr1  Tnfr2  
Pre-Ligand Assembly Domain-Derived Recombinant Proteins of TNFR2 Inhibits the Expansion of CD4+Foxp3+ Regulatory T Cells Journal article
WEN-WEI LI, CHUANGEN LI, YANG YANG, YIBO CHEN; Yexuan Zhang; Hong Cai; Chon Kit CHOU; Xin Chen; Yuanjia Hu*, ZHONGHAO CHEN, YANG GAO, YIRU WANG, XIN CHEN, Chon-Kit Chou. Pre-Ligand Assembly Domain-Derived Recombinant Proteins of TNFR2 Inhibits the Expansion of CD4+Foxp3+ Regulatory T Cells[J]. Journal of Leukocyte Biology, 2025.
Authors:  WEN-WEI LI;  CHUANGEN LI;  YANG YANG;  YIBO CHEN;   Yexuan Zhang;   Hong Cai;   Chon Kit CHOU;   Xin Chen;   Yuanjia Hu*;  ZHONGHAO CHEN; et al.
Favorite |   IF:3.6/5.2 | Submit date：2025/01/17
Anti-TNFR2 Antibody-Conjugated PLGA Nanoparticles for Targeted Delivery of Adriamycin in Mouse Colon Cancer Journal article
Li, Ping, Yang, Yang, Wang, Yifei, Zheng, Jingbin, Chen, Fengyang, Jiang, Mengmeng, Chou, Chon Kit, Cong, Weihong, Li, Zongjin, Chen, Xin. Anti-TNFR2 Antibody-Conjugated PLGA Nanoparticles for Targeted Delivery of Adriamycin in Mouse Colon Cancer[J]. Research, 2024, 7, 0444.
Authors:  Li, Ping;  Yang, Yang;  Wang, Yifei;  Zheng, Jingbin;  Chen, Fengyang; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:8.5/8.7 | Submit date：2024/10/10
Deubiquitinating enzymes: potential regulators of the tumor microenvironment and implications for immune evasion Review article
2024
Authors:  Hsu, Sheng Kai;  Chon-Kit Chou;  Lin, I. Ling;  Chang, Wen Tsan;  Kuo, I. Ying; et al.
Favorite | TC[WOS]:1 TC[Scopus]:2  IF:8.2/8.0 | Submit date：2024/05/16
Cytotoxic t Cell (Ctl)  Deubiquitinating Enzymes (Dubs)  Immune Evasion  Posttranslational Modification (Ptm)  Regulatory t Cell (Treg)  Tumor Microenvironment (Tme)  Tumor-associated Macrophage (Tam)  
Exosome-Modified Liposomes Targeted Delivery of Thalidomide to Regulate Treg Cells for Antitumor Immunotherapy Journal article
Yang,Yang, Wang,Qingfu, Zou,Huimin, Chou Chon-Kit, Chen Xin*. Exosome-Modified Liposomes Targeted Delivery of Thalidomide to Regulate Treg Cells for Antitumor Immunotherapy[J]. Pharmaceutics, 2023, 15(4), 1074.
Authors:  Yang,Yang;  Wang,Qingfu;  Zou,Huimin;  Chou Chon-Kit;  Chen Xin*
Favorite | TC[WOS]:5 TC[Scopus]:6  IF:4.9/5.5 | Submit date：2023/08/03
Exosome  Regulatory t Cells (Tregs)  Thalidomide  Tnfr2  
TNFR2 deficiency impairs the growth of mouse colon cancer Journal article
Li,Ping, Yang,Yang, Yang,Xinyu, Wang,Yifei, Chou,Chon Kit, Jiang,Mengmeng, Zheng,Jingbin, Chen,Fengyang, Chen,Xin*. TNFR2 deficiency impairs the growth of mouse colon cancer[J]. International Journal of Biological Sciences, 2023, 19(4), 1024-1035.
Authors:  Li,Ping;  Yang,Yang;  Yang,Xinyu;  Wang,Yifei;  Chou,Chon Kit; et al.
Favorite | TC[WOS]:9 TC[Scopus]:9  IF:8.2/8.3 | Submit date：2023/08/03
Tumor Necrosis Factor (Tnf)  Tumor Necrosis Factor Receptor Type Ii (Tnfr2)  Colon Cancer  Cancer Immunotherapy  
Phthalate derivative DEHP disturbs the antiproliferative effect of camptothecin in human lung cancer cells by attenuating DNA damage and activating Akt/NF-κB signaling pathway Journal article
Ritesh Urade, Chon-Kit Chou, Han-Lin Chou, Bing-Hung Chen, Tsu-Nai Wang, Eing-Mei Tsai, Chun-Tzu Hung, Shyh-Jong Wu, Chien-Chih Chiu. Phthalate derivative DEHP disturbs the antiproliferative effect of camptothecin in human lung cancer cells by attenuating DNA damage and activating Akt/NF-κB signaling pathway[J]. ENVIRONMENTAL TOXICOLOGY, 2022, 38(2), 332-342.
Authors:  Ritesh Urade;  Chon-Kit Chou;  Han-Lin Chou;  Bing-Hung Chen;  Tsu-Nai Wang; et al.
Favorite | TC[WOS]:10 TC[Scopus]:11  IF:4.4/4.2 | Submit date：2023/01/30
Autophagy  Chemoresistance  Nf-κb  Non-small Cell Lung Cancer  Phthalate  
Phenotypic changes in monocyte subsets are associated with excessive inflammation during hyperuricemia and modification with TCM in patient with hyperuricemia-related proinflammatory diseases Project
项目类型: SRG, 项目编号: SRG2022-00042-ICMS, 资助机构: UM, 2022-2025
Authors:  CHOU CHON KIT
Favorite |  | Submit date：2023/03/29
Distepharinamide, a novel dimeric proaporphine alkaloid from Diploclisia glaucescens, inhibits the differentiation and proliferative expansion of CD4+Foxp3+ regulatory T cells Journal article
Feng-Yang Chen, Chang-An Geng, Chon-Kit Chou, Jing-Bin Zheng, Yang Yang, Yi-Fei Wang, Tian-Ze Li, Ping Li, Ji-Jun Chen, Xin Chen*. Distepharinamide, a novel dimeric proaporphine alkaloid from Diploclisia glaucescens, inhibits the differentiation and proliferative expansion of CD4+Foxp3+ regulatory T cells[J]. Phytomedicine, 2022, 107, 154482.
Authors:  Feng-Yang Chen;  Chang-An Geng;  Chon-Kit Chou;  Jing-Bin Zheng;  Yang Yang; et al.
Favorite | TC[WOS]:1 TC[Scopus]:2  IF:6.7/6.2 | Submit date：2023/01/30
Cancer Immunotherapy  Dimeric Proaporphine Alkaloid  Diploclisia Glaucescens  Foxp3  Treg