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Recent advances in bioactivity-guided drug screening strategies for pre-clinical and clinical drug discovery Journal article
Chen, Simin, Shen, Chenxiao, Li, Wanyu, Fan, Yu, Yang, Dong Hua, Wang, Yitao, Feng, Ruibing, Li, Guodong, Zhong, Zhangfeng. Recent advances in bioactivity-guided drug screening strategies for pre-clinical and clinical drug discovery[J]. TrAC-Trends in Analytical Chemistry, 2024, 181, 118042.
Authors:  Chen, Simin;  Shen, Chenxiao;  Li, Wanyu;  Fan, Yu;  Yang, Dong Hua; et al.
Favorite | TC[WOS]:1 TC[Scopus]:0  IF:11.8/12.7 | Submit date：2024/12/05
Bioactivity-guided Drug Screening  Clinical Drugs  High-throughput Screening  Natural Products  
OGG1: An emerging multifunctional therapeutic target for the treatment of diseases caused by oxidative DNA damage Journal article
Zhong, Yunxiao, Zhang, Xinya, Feng, Ruibing, Fan, Yu, Zhang, Zhang, Zhang, Qing Wen, Wan, Jian Bo, Wang, Yitao, Yu, Hua, Li, Guodong. OGG1: An emerging multifunctional therapeutic target for the treatment of diseases caused by oxidative DNA damage[J]. Medicinal Research Reviews, 2024, 44(6), 2825-2848.
Authors:  Zhong, Yunxiao;  Zhang, Xinya;  Feng, Ruibing;  Fan, Yu;  Zhang, Zhang; et al.
Favorite | TC[WOS]:3 TC[Scopus]:3  IF:10.9/12.9 | Submit date：2024/11/05
8-oxoguanine DNA glycosylase 1  age-related disorders  inflammation  oxidative DNA damage-related diseases  tumors  
OGG1: An emerging multifunctional therapeutic target for the treatment of diseases caused by oxidative DNA damage Review article
2024
Authors:  Zhong, Yunxiao;  Zhang, Xinya;  Feng, Ruibing;  Fan, Yu;  Zhang, Zhang; et al.
Favorite | TC[WOS]:3 TC[Scopus]:3  IF:10.9/12.9 | Submit date：2024/09/03
8-oxoguanine Dna Glycosylase 1  Age-related Disorders  Inflammation  Oxidative Dna Damage-related Diseases  Tumors  
Encoding and display technologies for combinatorial libraries in drug discovery: The coming of age from biology to therapy Review article
2024
Authors:  Fan, Yu;  Feng, Ruibing;  Zhang, Xinya;  Wang, Zhen Liang;  Xiong, Feng; et al.
Favorite | TC[WOS]:9 TC[Scopus]:8  IF:14.7/14.1 | Submit date：2024/05/16
Drug Screening  Dna-encoded Chemical Libraries  Phage Display  Peptide-encoded Chemical Libraries  Clinical Drugs  
A Biomimetic Multifunctional Nanoframework for Symptom Relief and Restorative Treatment of Acute Liver Failure Journal article
Feng, Ruibing, Fan, Yu, Zhang, Xinya, Chen, Lanmei, Zhong, Zhang Feng, Wang, Yitao, Yu, Hua, Zhang, Qing Wen, Li, Guodong. A Biomimetic Multifunctional Nanoframework for Symptom Relief and Restorative Treatment of Acute Liver Failure[J]. ACS Nano, 2024, 18(7), 5951-5964.
Authors:  Feng, Ruibing;  Fan, Yu;  Zhang, Xinya;  Chen, Lanmei;  Zhong, Zhang Feng; et al.
Favorite | TC[WOS]:5 TC[Scopus]:6  IF:15.8/16.2 | Submit date：2024/05/16
Acute Liver Failure  Biomimetic Nanoparticle  Mesenchymal Stem Cell  N-acetylcysteine  Rhein  
Ginsenoside Rk2, a dehydroprotopanaxadiol saponin, alleviates alcoholic liver disease via regulating NLRP3 and NLRP6 inflammasome signaling pathways in mice Journal article
Jian Zou, Rujie Yang, Ruibing Feng, Jiayue Liu, Jian Bo Wan. Ginsenoside Rk2, a dehydroprotopanaxadiol saponin, alleviates alcoholic liver disease via regulating NLRP3 and NLRP6 inflammasome signaling pathways in mice[J]. Journal of Pharmaceutical Analysis, 2023, 13(9), 999-1012.
Authors:  Jian Zou;  Rujie Yang;  Ruibing Feng;  Jiayue Liu;  Jian Bo Wan
Favorite | TC[WOS]:11 TC[Scopus]:12  IF:6.1/6.8 | Submit date：2023/10/10
Alcoholic Liver Disease  Ginsenoside Rk2  Intestinal Barrier Dysfunction  Nlrp3 Inflammasome  Nlrp6 Inflammasome  
Total saponins from Panax japonicus attenuate acute alcoholic liver oxidative stress and hepatosteatosis by p62-related Nrf2 pathway and AMPK-ACC/PPARα axis in vivo and in vitro Journal article
Qiu,Ling, Feng,Ruibing, Wu,Qiu shuang, Wan,Jian bo, Zhang,Qing wen. Total saponins from Panax japonicus attenuate acute alcoholic liver oxidative stress and hepatosteatosis by p62-related Nrf2 pathway and AMPK-ACC/PPARα axis in vivo and in vitro[J]. Journal of Ethnopharmacology, 2023, 317.
Authors:  Qiu,Ling;  Feng,Ruibing;  Wu,Qiu shuang;  Wan,Jian bo;  Zhang,Qing wen
Favorite | TC[WOS]:10 TC[Scopus]:12  IF:4.8/4.8 | Submit date：2023/08/03
Anti-inebriation  Antioxidation  Hepatosteatosis  Panax Japonicus (T. Nees) C.a. Mey.  Saponin  
Long-Lived Second Near-Infrared Luminescent Probes: An Emerging Role in Time-Resolved Luminescence Bioimaging and Biosensing Journal article
Ruibing Feng, Guodong Li, Chung-Nga Ko, Zhang Zhang, Jian-Bo Wan, Qing-Wen Zhang. Long-Lived Second Near-Infrared Luminescent Probes: An Emerging Role in Time-Resolved Luminescence Bioimaging and Biosensing[J]. Small Structures, 2022, 4(2), 2200131.
Authors:  Ruibing Feng;  Guodong Li;  Chung-Nga Ko;  Zhang Zhang;  Jian-Bo Wan; et al.
Favorite | TC[WOS]:27 TC[Scopus]:27 | Submit date：2023/01/10
Bioimaging  Probes  Second Near-infrared Regions  Time-resolved Luminescence  Biosensing  
A bioactive ligand-conjugated iridium(III) metal-based complex as a Keap1–Nrf2 protein-protein interaction inhibitor against acetaminophen-induced acute liver injury Journal article
Li, Guodong, Liu, Hao, Feng, Ruibing, Kang, Tian Shu, Wang, Wanhe, Ko, Chung Nga, Wong, Chun Yuen, Ye, Min, Ma, Dik Lung, Wan, Jian Bo, Leung, Chung Hang. A bioactive ligand-conjugated iridium(III) metal-based complex as a Keap1–Nrf2 protein-protein interaction inhibitor against acetaminophen-induced acute liver injury[J]. Redox Biology, 2021, 48, 102129.
Authors:  Li, Guodong;  Liu, Hao;  Feng, Ruibing;  Kang, Tian Shu;  Wang, Wanhe; et al.
Favorite | TC[WOS]:28 TC[Scopus]:32  IF:10.7/11.7 | Submit date：2022/05/13
Inhibitor  Iridium(Iii) Complex  Kelch-like Ech-associated Protein 1  Liver Injury  Nuclear Factor E2-related Factor 2  
Oxidation of fish oil exacerbates alcoholic liver disease by enhancing intestinal dysbiosis in mice Journal article
Feng,Ruibing, Ma,Li Juan, Wang,Meng, Liu,Conghui, Yang,Rujie, Su,Huanxing, Yang,Yan, Wan,Jian Bo. Oxidation of fish oil exacerbates alcoholic liver disease by enhancing intestinal dysbiosis in mice[J]. Communications Biology, 2020, 3(1).
Authors:  Feng,Ruibing;  Ma,Li Juan;  Wang,Meng;  Liu,Conghui;  Yang,Rujie; et al.
Favorite | TC[WOS]:31 TC[Scopus]:34  IF:5.2/5.6 | Submit date：2021/03/01