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BET inhibition induces synthetic lethality in PTEN deficient colorectal cancers via dual action on p21CIP1/WAF1
Journal article
Ren, Guowen, Chen, Jinghong, Pu, Yue, Yang, Eun Ju, Tao, Shishi, Mou, Pui Kei, Chen, Li Jie, Zhu, Wenli, Chan, Kin Long, Luo, Guanghui, Deng, Chuxia, Shim, Joong Sup. BET inhibition induces synthetic lethality in PTEN deficient colorectal cancers via dual action on p21CIP1/WAF1[J]. International Journal of Biological Sciences, 2024, 20(6), 1978-1991.
Authors:
Ren, Guowen
;
Chen, Jinghong
;
Pu, Yue
;
Yang, Eun Ju
;
Tao, Shishi
; et al.
Favorite
|
TC[WOS]:
1
TC[Scopus]:
1
IF:
8.2
/
8.3
|
Submit date:2024/05/16
Akt
Bet
Colorectal Cancer
Myc
P21
PhosphorylAted P21 At Thr145
Pten
Synthetic Lethality
ER translocon inhibitor ipomoeassin F inhibits triple-negative breast cancer growth via blocking ER molecular chaperones
Journal article
Shishi Tao, Eun Ju Yang, Guanghui Zong, Pui Kei Mou, Guowen Ren, Yue Pu, Liang Chen, Ho Jeong Kwon, Jianhong Zhou, Zhijian Hu, Arman Khosravi, Qingyang Zhang, Yuchun Du, Wei Q. Shi, Joong Sup Shim. ER translocon inhibitor ipomoeassin F inhibits triple-negative breast cancer growth via blocking ER molecular chaperones[J]. Int J Biol Sci, 2023, 19(13), 4020-4035.
Authors:
Shishi Tao
;
Eun Ju Yang
;
Guanghui Zong
;
Pui Kei Mou
;
Guowen Ren
; et al.
Favorite
|
TC[WOS]:
0
TC[Scopus]:
0
IF:
8.2
/
8.3
|
Submit date:2023/08/30
Ipomoeassin f
Er Stress
Er Translocon
Tnbc
Pdia6
Pdia4
MDM2 inhibition is synthetic lethal with PTEN loss in colorectal cancer cells via the p53-dependent mechanism
Journal article
Guowen Ren, Eun Ju Yang, Shishi Tao, Pui Kei Mou, Yue Pu, Li-Jie Chen, Joong Sup Shim. MDM2 inhibition is synthetic lethal with PTEN loss in colorectal cancer cells via the p53-dependent mechanism[J]. Int J Biol Sci, 2023, 19(11), 3544-3557.
Authors:
Guowen Ren
;
Eun Ju Yang
;
Shishi Tao
;
Pui Kei Mou
;
Yue Pu
; et al.
Favorite
|
IF:
8.2
/
8.3
|
Submit date:2023/08/30
New Concept of Multi-State Diplexers Implemented on Planar and Cavity Circuits
Conference paper
Rui-Sen Chen, Sai-Wai Wong, Guowen Chen, Xiongmin Hu, Jing-Yu Lin, Lei Zhu, Yejun He. New Concept of Multi-State Diplexers Implemented on Planar and Cavity Circuits[C]:IEEE, 2019.
Authors:
Rui-Sen Chen
;
Sai-Wai Wong
;
Guowen Chen
;
Xiongmin Hu
;
Jing-Yu Lin
; et al.
Favorite
|
TC[WOS]:
0
TC[Scopus]:
0
|
Submit date:2021/03/09
Psoralidin induced reactive oxygen species (ROS)-dependent DNA damage and protective autophagy mediated by NOX4 in breast cancer cells
Journal article
Ren Guowen, Luo Weiwei, Sun Wen, Niu Yanan, Dik-Lung Ma, Leung Chung-Hang, Wang Yitao, Lu Jin-Jian, Chen Xiuping. Psoralidin induced reactive oxygen species (ROS)-dependent DNA damage and protective autophagy mediated by NOX4 in breast cancer cells[J]. Phytomedicine, 2016, 23(9), 939.
Authors:
Ren Guowen
;
Luo Weiwei
;
Sun Wen
;
Niu Yanan
;
Dik-Lung Ma
; et al.
Favorite
|
TC[WOS]:
45
TC[Scopus]:
47
IF:
6.7
/
6.2
|
Submit date:2018/10/31
Cell Death
Dna Damage
Nox4
Psoralidin
Ros
Chinese Medicine
Cucurbitacin B induces DNA damage and autophagy mediated by reactive oxygen species (ROS) in MCF-7 breast cancer cells
Journal article
Guowen Ren, Tongye Sha, Jiajie Guo, Wenxue Li, Jinjian Lu, Xiuping Chen. Cucurbitacin B induces DNA damage and autophagy mediated by reactive oxygen species (ROS) in MCF-7 breast cancer cells[J]. Journal of Natural Medicines, 2015, 69(4), 522-530.
Authors:
Guowen Ren
;
Tongye Sha
;
Jiajie Guo
;
Wenxue Li
;
Jinjian Lu
; et al.
Favorite
|
TC[WOS]:
50
TC[Scopus]:
56
|
Submit date:2018/12/28
Autophagy
Chinese Medicine
Cucurbitacin b
Dna Damage
Ros
Cell Death
Cucurbitacin B induces DNA damage, G2/M phase arrest, and apoptosis mediated by reactive oxygen species (ROS) in leukemia K562 cells
Journal article
Jiajie Guo, Wenwen Zhao, Wenhui Hao, Guowen Ren, Jinjian Lu, Xiuping Chen. Cucurbitacin B induces DNA damage, G2/M phase arrest, and apoptosis mediated by reactive oxygen species (ROS) in leukemia K562 cells[J]. Anti-Cancer Agents in Medicinal Chemistry, 2014, 14(8), 1146-1153.
Authors:
Jiajie Guo
;
Wenwen Zhao
;
Wenhui Hao
;
Guowen Ren
;
Jinjian Lu
; et al.
Favorite
|
TC[WOS]:
33
TC[Scopus]:
34
|
Submit date:2018/12/28
Cell Death
Cancer
Cucurbitacin b
Dna Damage
Ros
Chinese Medicine