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GSK3β 抑制剂和/或 HRR 抑制剂在制备治疗 FHIT 缺失型肺癌的药物中的应用 Patent
专利类型: 发明专利 Invention, 专利号: UMPT0737-2024, 申请日期: 2024-08,
Authors:  JOONG SUP SHIM;  SHISHI TAO
Adobe PDF | Favorite |  | Submit date：2024/08/29
BET inhibition induces synthetic lethality in PTEN deficient colorectal cancers via dual action on p21CIP1/WAF1 Journal article
Ren, Guowen, Chen, Jinghong, Pu, Yue, Yang, Eun Ju, Tao, Shishi, Mou, Pui Kei, Chen, Li Jie, Zhu, Wenli, Chan, Kin Long, Luo, Guanghui, Deng, Chuxia, Shim, Joong Sup. BET inhibition induces synthetic lethality in PTEN deficient colorectal cancers via dual action on p21CIP1/WAF1[J]. International Journal of Biological Sciences, 2024, 20(6), 1978-1991.
Authors:  Ren, Guowen;  Chen, Jinghong;  Pu, Yue;  Yang, Eun Ju;  Tao, Shishi; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:8.2/8.3 | Submit date：2024/05/16
Akt  Bet  Colorectal Cancer  Myc  P21  PhosphorylAted P21 At Thr145  Pten  Synthetic Lethality  
ER translocon inhibitor ipomoeassin F inhibits triple-negative breast cancer growth via blocking ER molecular chaperones Journal article
Shishi Tao, Eun Ju Yang, Guanghui Zong, Pui Kei Mou, Guowen Ren, Yue Pu, Liang Chen, Ho Jeong Kwon, Jianhong Zhou, Zhijian Hu, Arman Khosravi, Qingyang Zhang, Yuchun Du, Wei Q. Shi, Joong Sup Shim. ER translocon inhibitor ipomoeassin F inhibits triple-negative breast cancer growth via blocking ER molecular chaperones[J]. Int J Biol Sci, 2023, 19(13), 4020-4035.
Authors:  Shishi Tao;  Eun Ju Yang;  Guanghui Zong;  Pui Kei Mou;  Guowen Ren; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:8.2/8.3 | Submit date：2023/08/30
Ipomoeassin f  Er Stress  Er Translocon  Tnbc  Pdia6  Pdia4  
MDM2 inhibition is synthetic lethal with PTEN loss in colorectal cancer cells via the p53-dependent mechanism Journal article
Guowen Ren, Eun Ju Yang, Shishi Tao, Pui Kei Mou, Yue Pu, Li-Jie Chen, Joong Sup Shim. MDM2 inhibition is synthetic lethal with PTEN loss in colorectal cancer cells via the p53-dependent mechanism[J]. Int J Biol Sci, 2023, 19(11), 3544-3557.
Authors:  Guowen Ren;  Eun Ju Yang;  Shishi Tao;  Pui Kei Mou;  Yue Pu; et al.
Favorite |   IF:8.2/8.3 | Submit date：2023/08/30
TRIM59 guards ER proteostasis and prevents Bortezomib-mediated colorectal cancer (CRC) cells’ killing Journal article
Xuejia Feng, Gui Yang, Litian Zhang, Shishi Tao, Joong Sup SHIM, Liang Chen, Qingxia Wu. TRIM59 guards ER proteostasis and prevents Bortezomib-mediated colorectal cancer (CRC) cells’ killing[J]. INVESTIGATIONAL NEW DRUGS, 2022, 40(6), 1244-1253.
Authors:  Xuejia Feng;  Gui Yang;  Litian Zhang;  Shishi Tao;  Joong Sup SHIM; et al.
Favorite | TC[WOS]:3 TC[Scopus]:3  IF:3.0/2.9 | Submit date：2023/01/30
Trim59  Er-stress  Unfolded Protein Response  Er-associated Degradation  Bortezomib  Colorectal Cancer  
Aurora kinase A inhibition induces synthetic lethality in SMAD4-deficient colorectal cancer cells via spindle assembly checkpoint activation Journal article
Changxiang Shi, Shishi Tao, Guowen Ren, Eun Ju Yang, Xiaodong Shu, Pui Kei Mou, Yifan Liu, Yongjun Dang, Xiaoling Xu, Joong Sup Shim. Aurora kinase A inhibition induces synthetic lethality in SMAD4-deficient colorectal cancer cells via spindle assembly checkpoint activation[J]. Oncogene, 2022, 41(19), 2734-2748.
Authors:  Changxiang Shi;  Shishi Tao;  Guowen Ren;  Eun Ju Yang;  Xiaodong Shu; et al.
Favorite | TC[WOS]:6 TC[Scopus]:6  IF:6.9/7.5 | Submit date：2022/05/31
Natural products targeting cancer cell dependency Review article
2021
Authors:  Changxiang Shi;  Eun Ju Yang;  Shishi Tao;  Guowen Ren;  Pui Kei Mou; et al.
Favorite | TC[WOS]:8 TC[Scopus]:9  IF:2.1/2.5 | Submit date：2021/12/08
Aurora kinase A, a synthetic lethal target for precision cancer medicine Review article
2021
Authors:  Mou, Pui Kei;  Yang, Eun Ju;  Shi, Changxiang;  Ren, Guowen;  Tao, Shishi; et al.
Favorite | TC[WOS]:65 TC[Scopus]:64  IF:9.5/11.7 | Submit date：2021/12/07