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Activation of notch 3/c-MYC/CHOP axis regulates apoptosis and promotes sensitivity of lung cancer cells to mTOR inhibitor everolimus Journal article
Li,Ting, Xu,Xiao Huang, Guo,Xia, Yuan,Tao, Tang,Zheng Hai, Jiang,Xiao Ming, Xu,Yu Lian, Zhang,Le Le, Chen,Xiuping, Zhu,Hong, Shi,Jia Jie, Lu,Jin Jian. Activation of notch 3/c-MYC/CHOP axis regulates apoptosis and promotes sensitivity of lung cancer cells to mTOR inhibitor everolimus[J]. Biochemical Pharmacology, 2020, 175.
Authors:  Li,Ting;  Xu,Xiao Huang;  Guo,Xia;  Yuan,Tao;  Tang,Zheng Hai; et al.
Favorite | TC[WOS]:17 TC[Scopus]:19  IF:5.3/5.2 | Submit date：2021/03/01
Lung Cancer  Notch 3  C-myc  Chop  Apoptosis  
MLKL mediates apoptosis via a mutual regulation with PERK/eIF2α pathway in response to reactive oxygen species generation Journal article
Wen-Xiang Cao, Ting Li, Zheng-Hai Tang, Le-Le Zhang, Zhao-Yu Wang, Xia Guo, Min-Xia Su, Xiuping Chen, Jin-Jian Lu. MLKL mediates apoptosis via a mutual regulation with PERK/eIF2α pathway in response to reactive oxygen species generation[J]. Apoptosis, 2018, 23(9-10), 521-531.
Authors:  Wen-Xiang Cao;  Ting Li;  Zheng-Hai Tang;  Le-Le Zhang;  Zhao-Yu Wang; et al.
Favorite | TC[WOS]:13 TC[Scopus]:14 | Submit date：2018/12/28
Apoptosis  Chelerythrine  Eif2α  Mlkl  Ros  
MLKL mediates apoptosis via a mutual regulation with PERK/eIF2 alpha pathway in response to reactive oxygen species generation Journal article
Wen‑Xiang Cao, Ting Li, Zheng‑Hai Tang, Le‑Le Zhang, Zhao‑Yu Wang, Xia Guo, Min‑Xia Su, Xiuping Chen, Jin‑Jian Lu. MLKL mediates apoptosis via a mutual regulation with PERK/eIF2 alpha pathway in response to reactive oxygen species generation[J]. APOPTOSIS, 2018, 23(9-10), 521-531.
Authors:  Wen‑Xiang Cao;  Ting Li;  Zheng‑Hai Tang;  Le‑Le Zhang;  Zhao‑Yu Wang; et al.
Favorite | TC[WOS]:13 TC[Scopus]:14  IF:6.1/5.6 | Submit date：2020/01/09
Mlkl  Eif2α  Ros  Apoptosis  Chelerythrine  
Osimertinib resistance in non-small cell lung cancer: Mechanisms and therapeutic strategies Journal article
Tang, Zheng-Hai, Lu, Jin-Jian. Osimertinib resistance in non-small cell lung cancer: Mechanisms and therapeutic strategies[J]. CANCER LETTERS, 2018, 420, 242-246.
Authors:  Tang, Zheng-Hai;  Lu, Jin-Jian
Favorite | TC[WOS]:100 TC[Scopus]:109  IF:9.1/8.3 | Submit date：2018/10/30
Osimertinib  Azd9291  Egfr Tki  Resistant Mechanisms  Therapeutic Strategies  
Increased expression of IRE1α associates with the resistant mechanism of osimertinib (AZD9291)-resistant non-small cell lung cancer HCC827/OSIR cells Journal article
Zheng-hai Tang, Min-Xia Su, Xia Guo, Xiao-Ming Jiang, Lin Jia, Xiuping Chen, Jin-Jian Lu. Increased expression of IRE1α associates with the resistant mechanism of osimertinib (AZD9291)-resistant non-small cell lung cancer HCC827/OSIR cells[J]. Anti-Cancer Agents in Medicinal Chemistry, 2018, 18(4), 550-555.
Authors:  Zheng-hai Tang;  Min-Xia Su;  Xia Guo;  Xiao-Ming Jiang;  Lin Jia; et al.
Favorite | TC[WOS]:0 TC[Scopus]:18 | Submit date：2018/12/28
Azd9291  Egfr  Ire1α  Lune Cancer  Nsclc  Osimertinib  
Identification of a novel autophagic inhibitor cepharanthine to enhance the anti-cancer property of dacomitinib in non-small cell lung cancer Journal article
Tang, Zheng-Hai, Cao, Wen-Xiang, Guo, Xia, Dai, Xiao-Yang, Lu, Jia-Hong, Chen, Xiuping, Zhu, Hong, Lu, Jin-Jian. Identification of a novel autophagic inhibitor cepharanthine to enhance the anti-cancer property of dacomitinib in non-small cell lung cancer[J]. CANCER LETTERS, 2018, 412, 1-9.
Authors:  Tang, Zheng-Hai;  Cao, Wen-Xiang;  Guo, Xia;  Dai, Xiao-Yang;  Lu, Jia-Hong; et al.
Favorite | TC[WOS]:36 TC[Scopus]:38  IF:9.1/8.3 | Submit date：2018/10/30
Cepharanthine  Autophagy  Lysosome  Dacomitinib  Nsclc  
Baicalein protects tert-butyl hydroperoxide-induced hepatotoxicity dependent of reactive oxygen species removal Journal article
Wang, Ya-Fang, Tang, Zheng-Hai, Li, Ting, Xu, Xiao-Huang, Chen, Xiuping, Wang, Ying, Wang, Yi-Tao, Lu, Jin-Jian. Baicalein protects tert-butyl hydroperoxide-induced hepatotoxicity dependent of reactive oxygen species removal[J]. MOLECULAR MEDICINE REPORTS, 2017, 16(6), 8392-8398.
Authors:  Wang, Ya-Fang;  Tang, Zheng-Hai;  Li, Ting;  Xu, Xiao-Huang;  Chen, Xiuping; et al.
Favorite | TC[WOS]:4 TC[Scopus]:5  IF:3.4/3.0 | Submit date：2018/10/30
Baicalein  Liver Protection  Reactive Oxygen Species  Apoptosis  
The effects and mechanisms of two main constituents from Glycyrrhiza uralensis Fisch-induced autophagy in non-small cell lung cancer Conference paper
Tang, Zheng-Hai, Zhang, Le-Le, Chen, Xin, Chen, Xiuping, Wang, Yitao, Lu, Jin-Jian. The effects and mechanisms of two main constituents from Glycyrrhiza uralensis Fisch-induced autophagy in non-small cell lung cancer[C], THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND:PERGAMON-ELSEVIER SCIENCE LTD, 2017, 123-123.
Authors:  Tang, Zheng-Hai;  Zhang, Le-Le;  Chen, Xin;  Chen, Xiuping;  Wang, Yitao; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0 | Submit date：2018/10/30
Induction of reactive oxygen species-stimulated distinctive autophagy by chelerythrine in non-small cell lung cancer cells Journal article
Tang, Zheng-Hai, Cao, Wen-Xiang, Wang, Zhao-Yu, Lu, Jia-Hong, Liu, Bo, Chen, Xiuping, Lu, Jin-Jian. Induction of reactive oxygen species-stimulated distinctive autophagy by chelerythrine in non-small cell lung cancer cells[J]. REDOX BIOLOGY, 2017, 12, 367-376.
Authors:  Tang, Zheng-Hai;  Cao, Wen-Xiang;  Wang, Zhao-Yu;  Lu, Jia-Hong;  Liu, Bo; et al.
Favorite | TC[WOS]:56 TC[Scopus]:59  IF:10.7/11.7 | Submit date：2018/10/30
Chelerythrine  Autophagy  Apoptosis  Ros  Nsclc  
Chikusetsusaponin IVa methyl ester induces G1 cell cycle arrest, triggers apoptosis and inhibits migration and invasion in ovarian cancer cells Journal article
Chen, Xin, Wu, Qiu-Shuang, Meng, Fan-Cheng, Tang, Zheng-Hai, Chen, Xiuping, Lin, Li-Gen, Chen, Ping, Qiang, Wen-An, Wang, Yi-Tao, Zhang, Qing-Wen, Lu, Jin-Jian. Chikusetsusaponin IVa methyl ester induces G1 cell cycle arrest, triggers apoptosis and inhibits migration and invasion in ovarian cancer cells[J]. PHYTOMEDICINE, 2017, 29(13), 1555-1565.
Authors:  Chen, Xin;  Wu, Qiu-Shuang;  Meng, Fan-Cheng;  Tang, Zheng-Hai;  Chen, Xiuping; et al.
Favorite | TC[WOS]:36 TC[Scopus]:33  IF:6.7/6.2 | Submit date：2018/10/30
Panacis Japonici Rhizoma  Chikusetsusaponin Iva Methyl Ester  Ovarian Cancer  Cell Cycle Arrest  Apoptosis  Metastasis