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Artemisinin inhibits neuronal ferroptosis in Alzheimer's disease models by targeting KEAP1 Journal article
Peng-xi Deng, Marta Silva, Na Yang, Qing Wang, Xin Meng, Ke-qiang Ye, Hong-chang Gao, ZHENG WENHUA. Artemisinin inhibits neuronal ferroptosis in Alzheimer's disease models by targeting KEAP1[J]. Acta Pharmacologica Sinica, 2024.
Authors:  Peng-xi Deng;  Marta Silva;  Na Yang;  Qing Wang;  Xin Meng; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:6.9/7.6 | Submit date:2024/08/31
Alzheimer's Disease  Artemisinin  Ferroptosis  Keap1  Nrf2  Hippocampus  
Artemisinin protected human retinal pigment epithelial cells from Amiodarone-induced oxidative damage via CaMKK2/AMPK/Nrf2 signaling pathway Conference paper
Chao Yang, ZHENG WENHUA. Artemisinin protected human retinal pigment epithelial cells from Amiodarone-induced oxidative damage via CaMKK2/AMPK/Nrf2 signaling pathway[C], 2024.
Authors:  Chao Yang;  ZHENG WENHUA
Favorite |  | Submit date:2024/08/31
Artemisinin  Amiodarone  Human Retinal Pigment Epithelium Cells  Oxidative Damage  Ampk  
Artemisinin conferred cytoprotection to human retinal pigment epithelial cells exposed to amiodarone-induced oxidative insult by activating the CaMKK2/AMPK/Nrf2 pathway Journal article
Chao YANG, Xia ZHAO, Wenshu ZHOU, Qin LI, Philip LAZAROVICI, ZHENG WENHUA. Artemisinin conferred cytoprotection to human retinal pigment epithelial cells exposed to amiodarone-induced oxidative insult by activating the CaMKK2/AMPK/Nrf2 pathway[J]. Journal of Translational Medicine, 2024, 22(1), 844.
Authors:  Chao YANG;  Xia ZHAO;  Wenshu ZHOU;  Qin LI;  Philip LAZAROVICI; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:6.1/6.2 | Submit date:2024/08/22
Amiodarone  Ampk  Artemisinin  Human Retinal Pigment Epithelial Cells  Ocular Toxicity  Oxidative Damage  
Artemisinins suppress melanoma recurrence and metastasis after radical surgery by inhibiting the c-KIT/PI3K/AKT signaling pathway Conference paper
Zhiwei Zhou, ZHENG WENHUA. Artemisinins suppress melanoma recurrence and metastasis after radical surgery by inhibiting the c-KIT/PI3K/AKT signaling pathway[C], 2024.
Authors:  Zhiwei Zhou;  ZHENG WENHUA
Favorite |  | Submit date:2024/08/31
Artemisinin  Melanoma  Post-surgery Model  C-kit  Akt  
Artemisinin protects against neural injury by targeting KEAP1 to inhibit ferroptosis in Alzheimer’s disease models Conference paper
Pengxi DENG, ZHENG WENHUA. Artemisinin protects against neural injury by targeting KEAP1 to inhibit ferroptosis in Alzheimer’s disease models[C], 2024.
Authors:  Pengxi DENG;  ZHENG WENHUA
Favorite |  | Submit date:2024/08/31
Artemisinin, Ferroptosis, Keap1, Nrf2, Alzheimer's Disease (Ad).  
Artemisinin Alleviates Astrocyte Over-Activation and Neuroinflammation by modulating the IRE1/NF-κB Signaling Pathway in in vitro and in vivo Alzheimer's Disease Models Conference paper
Lei Chen, ZHENG WENHUA. Artemisinin Alleviates Astrocyte Over-Activation and Neuroinflammation by modulating the IRE1/NF-κB Signaling Pathway in in vitro and in vivo Alzheimer's Disease Models[C], 2024.
Authors:  Lei Chen;  ZHENG WENHUA
Favorite |  | Submit date:2024/08/31
Alzheimer’s Disease  Endoplasmic Reticulum Stress  Artemisinin  Astrocyte  3xtg Ad Mice  Neuroinflammation  Ire1  Nf-κb.  
Artemisinin diminished the hyperphosphorylation of Tau induced by Aβ1-42 via the AKT/GSK-3β pathway in vitro and in vivo Alzheimer's disease modle Conference paper
Yitian Chen, Wenhua Zheng. Artemisinin diminished the hyperphosphorylation of Tau induced by Aβ1-42 via the AKT/GSK-3β pathway in vitro and in vivo Alzheimer's disease modle[C], 2024.
Authors:  Yitian Chen;  Wenhua Zheng
Favorite |  | Submit date:2024/08/31
Alzheimer’s Disease, Aβ, Tau Hyperphosphorylation, Artemisinin, Gsk-3β, P13k/akt  
Artemisinin Confers Cytoprotection toward Hydrogen Peroxide-Induced Cell Apoptosis in Retinal Pigment Epithelial Cells in Correlation with the Increased Acetylation of Histone H4 at Lysine 8 Journal article
Yang, Chao, Ge, Lijun, Yu, Xiyong, Lazarovici, Philip, Zheng, Wenhua. Artemisinin Confers Cytoprotection toward Hydrogen Peroxide-Induced Cell Apoptosis in Retinal Pigment Epithelial Cells in Correlation with the Increased Acetylation of Histone H4 at Lysine 8[J]. Molecules, 2024, 29(8), 1789.
Authors:  Yang, Chao;  Ge, Lijun;  Yu, Xiyong;  Lazarovici, Philip;  Zheng, Wenhua
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:4.2/4.6 | Submit date:2024/05/16
Acetyl-h4 (Lys 8)  Apoptosis  Artemisinin  Cytoprotection  H2o2  Retinal Pigment Epithelial Cells  
Artemisinin protected human retinal pigment epithelial cells from Amiodarone-induced oxidative damage via CaMKK2/AMPK/Nrf2 signaling pathway Conference paper
Chao Yang, Wenhua Zheng. Artemisinin protected human retinal pigment epithelial cells from Amiodarone-induced oxidative damage via CaMKK2/AMPK/Nrf2 signaling pathway[C], 2024.
Authors:  Chao Yang;  Wenhua Zheng
Favorite |  | Submit date:2024/08/31
Artemisinin  Amiodarone  Human Retinal Pigment Epithelium Cells  Oxidative Damage  Ampk  
Artemisinin Confers Neuroprotection against 6-OHDA-Induced Neuronal Injury In Vitro and In Vivo through Activation of the ERK1/2 Pathway Journal article
Qin Li, Shuai Li, Jiankang Fang, Chao Yang, Xia Zhao, Qing Wang, Wenshu Zhou, Zheng WH(鄭文華). Artemisinin Confers Neuroprotection against 6-OHDA-Induced Neuronal Injury In Vitro and In Vivo through Activation of the ERK1/2 Pathway[J]. Molecules, 2023, 28(14).
Authors:  Qin Li;  Shuai Li;  Jiankang Fang;  Chao Yang;  Xia Zhao; et al.
Favorite | TC[WOS]:5 TC[Scopus]:5  IF:4.2/4.6 | Submit date:2023/08/14
Artemisinin  6-ohda  Mptp/mpp++  Apoptosis  Parkinson’s Disease