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Recent advances in bioactivity-guided drug screening strategies for pre-clinical and clinical drug discovery Journal article
Chen, Simin, Shen, Chenxiao, Li, Wanyu, Fan, Yu, Yang, Dong Hua, Wang, Yitao, Feng, Ruibing, Li, Guodong, Zhong, Zhangfeng. Recent advances in bioactivity-guided drug screening strategies for pre-clinical and clinical drug discovery[J]. TrAC-Trends in Analytical Chemistry, 2024, 181, 118042.
Authors:  Chen, Simin;  Shen, Chenxiao;  Li, Wanyu;  Fan, Yu;  Yang, Dong Hua; et al.
Favorite | TC[WOS]:1 TC[Scopus]:0  IF:11.8/12.7 | Submit date：2024/12/05
Bioactivity-guided Drug Screening  Clinical Drugs  High-throughput Screening  Natural Products  
Exploration of natural flavones’ bioactivity and bioavailability in chronic inflammation induced-type-2 diabetes mellitus Journal article
Miao, Lingchao, Liu, Conghui, Cheong, Meang Sam, Zhong, Ruting, Tan, Yi, Rengasamy, Kannan R.R., Leung, Susan Wai Sum, Cheang, Wai San, Xiao, Jianbo. Exploration of natural flavones’ bioactivity and bioavailability in chronic inflammation induced-type-2 diabetes mellitus[J]. Critical Reviews in Food Science and Nutrition, 2023, 63(33), 11640-11667.
Authors:  Miao, Lingchao;  Liu, Conghui;  Cheong, Meang Sam;  Zhong, Ruting;  Tan, Yi; et al.
Favorite | TC[WOS]:14 TC[Scopus]:14  IF:7.3/10.3 | Submit date：2022/08/05
Bioactivity  Bioavailability  Flavones  Inflammation  Type 2 Diabetes Mellitus  
Bioactivity-based molecular networking-guided identification of guttiferone J from Garcinia cambogia as an anti-obesity candidate Journal article
Feng, Zheling, Chen, Jiali, Chen, Cheng, Feng, Lu, Wang, Rui, Zhu, Jianzhong, Lou, Ruohan, Liu, Jia, Ye, Yang, Lin, Ligen. Bioactivity-based molecular networking-guided identification of guttiferone J from Garcinia cambogia as an anti-obesity candidate[J]. British Journal of Pharmacology, 2022, 180(5), 589-608.
Authors:  Feng, Zheling;  Chen, Jiali;  Chen, Cheng;  Feng, Lu;  Wang, Rui; et al.
Favorite | TC[WOS]:9 TC[Scopus]:11  IF:6.8/7.4 | Submit date：2023/04/03
Anti-obesity  Bioactivity-based Molecular Networking  Garcinia Cambogia  Guttiferone j  Sirtuin 3  White Adipose Tissue Browning  
Effects of steam on polysaccharides from Polygonatum cyrtonema based on saccharide mapping analysis and pharmacological activity assays Journal article
Chen, Zherui, Zhu, Baojie, Chen, Zhixin, Cao, Wen, Wang, Junqiao, Li, Shaoping, Zhao, Jing. Effects of steam on polysaccharides from Polygonatum cyrtonema based on saccharide mapping analysis and pharmacological activity assays[J]. Chinese Medicine (United Kingdom), 2022, 17(1), 97.
Authors:  Chen, Zherui;  Zhu, Baojie;  Chen, Zhixin;  Cao, Wen;  Wang, Junqiao; et al.
Favorite | TC[WOS]:15 TC[Scopus]:18  IF:5.3/5.5 | Submit date：2022/10/21
Polygonatum Cyrtonema  Polysaccharides  Steam  Chemical Composition  Bioactivity  Saccharide Mapping  
Design, synthesis and antitumor evaluation of novel 1H-indole-2-carboxylic acid derivatives targeting 14-3-3η protein Journal article
Gao, Zhenxiong, Fan, Tingting, Chen, Linbo, Yang, Mengchu, Wai Wong, Vincent Kam, Chen, Dawei, Liu, Zijian, Zhou, Yaoyao, Wu, Weibin, Qiu, Zixuan, Zhang, Cunlong, Li, Yuan, Jiang, Yuyang. Design, synthesis and antitumor evaluation of novel 1H-indole-2-carboxylic acid derivatives targeting 14-3-3η protein[J]. European Journal of Medicinal Chemistry, 2022, 238.
Authors:  Gao, Zhenxiong;  Fan, Tingting;  Chen, Linbo;  Yang, Mengchu;  Wai Wong, Vincent Kam; et al.
Favorite | TC[WOS]:4 TC[Scopus]:4  IF:6.0/6.1 | Submit date：2023/01/30
14-3-3η Protein  Antitumor Bioactivity  Drug Design  Hepatocellular Carcinoma  Novel Target  
Jiedu Huoxue Decoction for Cytokine Storm and Thrombosis in Severe COVID-19: A Combined Bioinformatics and Computational Chemistry Approach Journal article
Liu, Ying, Yan, Han, Jia, Hui Bin, Pan, Li, Liu, Jia Zheng, Zhang, Ya Wen, Wang, Jing, Qin, Dao Gang, Ma, Lei, Wang, Ting. Jiedu Huoxue Decoction for Cytokine Storm and Thrombosis in Severe COVID-19: A Combined Bioinformatics and Computational Chemistry Approach[J]. Natural Product Communications, 2022, 17(4).
Authors:  Liu, Ying;  Yan, Han;  Jia, Hui Bin;  Pan, Li;  Liu, Jia Zheng; et al.
Favorite | TC[WOS]:0 TC[Scopus]:1  IF:1.5/1.5 | Submit date：2023/01/30
Bioactivity  Bioinformatics  Computational Chemistry  Covid-19  Cytokine Storm  Jiedu Huoxue Decoction  Molecular Dynamics Simulation  Thrombosis  
Bioactivity guided isolation and identification of phenolic compounds from Citrus aurantium L. with anti-colorectal cancer cells activity by UHPLC-Q-TOF/MS Journal article
Gao, Li, Gou, Na, Amakye, William Kwame, Wu, Jianlin, Ren, Jiaoyan. Bioactivity guided isolation and identification of phenolic compounds from Citrus aurantium L. with anti-colorectal cancer cells activity by UHPLC-Q-TOF/MS[J]. Current Research in Food Science, 2022, 5, 2251-2260.
Authors:  Gao, Li;  Gou, Na;  Amakye, William Kwame;  Wu, Jianlin;  Ren, Jiaoyan
Favorite | TC[WOS]:6 TC[Scopus]:8 | Submit date：2023/01/30
Bioactivity Guided Isolation  Citrus Aurantium L.  Colorectal Cancer  Phenolic Compounds  Wnt Signalling  
A four-component combination derived from Huang-Qin Decoction significantly enhances anticancer activity of irinotecan Journal article
XU, Dou Dou, HOU, Xiao Ying, WANG, Ou, WANG, Di, LI, Dan Ting, QIN, Si Yuan, LV, Bo, DAI, Xiao Min, ZHANG, Zun Jian, WAN, Jian Bo, XU, Feng Guo. A four-component combination derived from Huang-Qin Decoction significantly enhances anticancer activity of irinotecan[J]. Chinese Journal of Natural Medicines, 2021, 19(5), 364-375.
Authors:  ; et al.
Favorite | TC[WOS]:21 TC[Scopus]:22  IF:4.0/3.7 | Submit date：2021/12/07
Active Components  Bioactivity Contribution  Huang-qin Decoction  Irinotecan  Toxicity Attenuating And Efficacy Enhancing  
A pharmacological review of dicoumarol: An old natural anticoagulant agent Journal article
Chong Sun, Wenwen Zhao, Xumei Wang, Yinxiang Sun, Xiuping Chen. A pharmacological review of dicoumarol: An old natural anticoagulant agent[J]. PHARMACOLOGICAL RESEARCH, 2020, 160, 105193.
Authors:  Chong Sun;  Wenwen Zhao;  Xumei Wang;  Yinxiang Sun;  Xiuping Chen
Favorite | TC[WOS]:38 TC[Scopus]:52  IF:9.1/9.0 | Submit date：2021/03/01
Bioactivity  Dicoumarol  Pharmacokinetic  Side Effects  
Advances on application of fenugreek seeds as functional foods: Pharmacology, clinical application, products, patents and market Journal article
Dongning Yao, Bingyu Zhang, Jianfan Zhu, Qianru Zhang, Yuanjia Hu, Shengpeng Wang, Yitao Wang, Hui Cao, Jianbo Xiao. Advances on application of fenugreek seeds as functional foods: Pharmacology, clinical application, products, patents and market[J]. Critical Reviews in Food Science and Nutrition, 2020, 60(14), 2342-2352.
Authors:  Dongning Yao;  Bingyu Zhang;  Jianfan Zhu;  Qianru Zhang;  Yuanjia Hu; et al.
Favorite | TC[WOS]:39 TC[Scopus]:52  IF:7.3/10.3 | Submit date：2020/03/27
Fenugreek Seeds  Foods  Bioactivity  Clinical Application  Products  Markets And Patents