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Development of small molecule inhibitors targeting RNA helicase DHX33 as anti-cancer agents Journal article
Wang, Yingcai, Nie, Guangli, Wang, Xingshun, Ge, Wei, Zhang, Yandong. Development of small molecule inhibitors targeting RNA helicase DHX33 as anti-cancer agents[J]. Bioorganic and Medicinal Chemistry Letters, 2023, 96, 129505.
Authors:  Wang, Yingcai;  Nie, Guangli;  Wang, Xingshun;  Ge, Wei;  Zhang, Yandong
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:2.5/2.4 | Submit date：2023/12/04
Cancer  Dhx33  Rna Helicase  Inhibitor High Throughput Screening (Hts)  
Development of a sensitive luminescent probe to uncover new BRD4 inhibitors in living cells Journal article
Song, Ying Qi, Wu, Ke Jia, Zhang, Zhiming, Liu, Tzu-Ming, Ko, Chung Nga, Zhu, Wei Guo, Ma, Dik Lung, Wang, Wanhe, Leung, Chung Hang. Development of a sensitive luminescent probe to uncover new BRD4 inhibitors in living cells[J]. Chemical Engineering Journal, 2023, 463, 142356.
Authors:  Song, Ying Qi;  Wu, Ke Jia;  Zhang, Zhiming;  Liu, Tzu-Ming;  Ko, Chung Nga; et al.
Favorite | TC[WOS]:7 TC[Scopus]:7  IF:13.3/13.2 | Submit date：2023/06/05
Azelastine  Brd4  Drug Screening  Inhibitor  Luminescent  Probe  
Discovery of novel anti-tumor compounds targeting PARP-1 with induction of autophagy through in silico and in vitro screening Journal article
Shi, Danfeng, Pang, Qianqian, Qin, Qianyu, Yao, Xinsheng, Yao, Xiaojun, Yu, Yang. Discovery of novel anti-tumor compounds targeting PARP-1 with induction of autophagy through in silico and in vitro screening[J]. Frontiers in Pharmacology, 2022, 13.
Authors:  Shi, Danfeng;  Pang, Qianqian;  Qin, Qianyu;  Yao, Xinsheng;  Yao, Xiaojun; et al.
Favorite | TC[WOS]:3 TC[Scopus]:4  IF:4.4/5.0 | Submit date：2023/01/31
allosteric  anti-tumor  autophagy  in silico screening  PARP-1 inhibitor  
Adsorbed hollow fiber immobilized tyrosinase for the screening of enzyme inhibitors from Pueraria lobata extract Journal article
Zhao,Cong Peng, Yin,Shi Jun, Chen,Guo Ying, Wang,Yuan, Chen,Hua, Zhao,Jing, Yang,Feng Qing. Adsorbed hollow fiber immobilized tyrosinase for the screening of enzyme inhibitors from Pueraria lobata extract[J]. Journal of Pharmaceutical and Biomedical Analysis, 2020, 193, 113743.
Authors:  Zhao,Cong Peng;  Yin,Shi Jun;  Chen,Guo Ying;  Wang,Yuan;  Chen,Hua; et al.
Favorite | TC[WOS]:18 TC[Scopus]:24  IF:3.1/3.1 | Submit date：2021/03/02
Adsorbed Hollow Fibers  Enzyme Immobilization  Inhibitor Screening  Pueraria Lobata  Tyrosinase  
LC-MS-based multivariate statistical analysis for the screening of potential thrombin/factor Xa inhibitors from Radix Salvia Miltiorrhiza Journal article
Yang,Yi Yao, Wu,Zhao Yu, Zhang,Hao, Yin,Shi Jun, Xia,Fang Bo, Zhang,Qian, Wan,Jian Bo, Gao,Jian Li, Yang,Feng Qing. LC-MS-based multivariate statistical analysis for the screening of potential thrombin/factor Xa inhibitors from Radix Salvia Miltiorrhiza[J]. Chinese Medicine, 2020, 15(1).
Authors:  Yang,Yi Yao;  Wu,Zhao Yu;  Zhang,Hao;  Yin,Shi Jun;  Xia,Fang Bo; et al.
Favorite | TC[WOS]:12 TC[Scopus]:18  IF:5.3/5.5 | Submit date：2021/03/02
Radix Salvia Miltiorrhiza  Thrombin  Factor Xa  Inhibitor Screening  Multivariate Statistical Analysis  Molecular Docking  
Identification of novel natural compound inhibitors for human complement component 5a receptor by homology modeling and virtual screening Journal article
Shaikh F., Siu S.W.I.. Identification of novel natural compound inhibitors for human complement component 5a receptor by homology modeling and virtual screening[J]. Medicinal Chemistry Research, 2016, 25(8), 1564-1573.
Authors:  Shaikh F.;  Siu S.W.I.
Favorite | TC[WOS]:15 TC[Scopus]:17 | Submit date：2019/04/04
C5ar  Homology Modeling  Mm-gbsa  Molecular Docking  Natural Compound Inhibitor  Virtual Screening  
Pharmacophore modeling for the identification of small-molecule inhibitors of TACE Journal article
Liu L.-J., Leung K.-H., Lin S., Chan D.S.-H., Susanti D., Rao W., Chan P.W.H., Ma D.-L., Leung C.-H.. Pharmacophore modeling for the identification of small-molecule inhibitors of TACE[J]. Methods, 2015, 71(C), 92-97.
Authors:  Liu L.-J.;  Leung K.-H.;  Lin S.;  Chan D.S.-H.;  Susanti D.; et al.
Favorite | TC[WOS]:3 TC[Scopus]:2 | Submit date：2018/11/06
Inhibitor  Pharmacophore  Tace  Tumor Necrosis Factor  Virtual Screening  
Structure-based repurposing of FDA-approved drugs as inhibitors of NEDD8-activating enzyme Journal article
Zhong H.-J., Liu L.-J., Chan D.S.-H., Wang H.-M., Chan P.W.H., Ma D.-L., Leung C.-H.. Structure-based repurposing of FDA-approved drugs as inhibitors of NEDD8-activating enzyme[J]. Biochimie, 2014, 102(1), 211-215.
Authors:  Zhong H.-J.;  Liu L.-J.;  Chan D.S.-H.;  Wang H.-M.;  Chan P.W.H.; et al.
Favorite | TC[WOS]:26 TC[Scopus]:27 | Submit date：2018/11/06
Inhibitor  Nedd8-activating Enzyme  Repurposing  Structure-based  Virtual Screening