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Skin-Resident γδ T Cells Mediate Potent and Selective Antitumor Cytotoxicity through Directed Chemotactic Migration and Mobilization of Cytotoxic Granules Journal article
Yang, Jiacai, Liu, Zhihui, Hu, Xiaohong, Zhang, Xiaorong, Huang, Yong, Chen, Yunxia, Chen, Cheng, Shang, Ruoyu, Tang, Yuanyang, Hu, Wengang, Wang, Jue, Shen, Han Ming, Hu, Jun, He, Weifeng. Skin-Resident γδ T Cells Mediate Potent and Selective Antitumor Cytotoxicity through Directed Chemotactic Migration and Mobilization of Cytotoxic Granules[J]. Journal of Investigative Dermatology, 2024.
Authors:  Yang, Jiacai;  Liu, Zhihui;  Hu, Xiaohong;  Zhang, Xiaorong;  Huang, Yong; et al.
Favorite | TC[Scopus]:0  IF:5.7/6.6 | Submit date：2025/01/13
Antitumor  Dendritic Epidermal t Cells  Granzyme b  Mtor  Perforin  
Tetramethylpyrazine Analogue T-006 Protects Neuronal and Endothelial Cells Against Oxidative Stress via PI3K/AKT/mTOR and Nrf2 Signaling Journal article
Zhang, Guiliang, Liang, Zirong, Wang, Yuqiang, Zhang, Zaijun, Hoi, Pui Man. Tetramethylpyrazine Analogue T-006 Protects Neuronal and Endothelial Cells Against Oxidative Stress via PI3K/AKT/mTOR and Nrf2 Signaling[J]. Antioxidants, 2024, 13(10), 1272.
Authors:  Zhang, Guiliang;  Liang, Zirong;  Wang, Yuqiang;  Zhang, Zaijun;  Hoi, Pui Man
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:6.0/6.7 | Submit date：2024/12/05
Tetramethylpyrazine Analogue T-006  Oxidative Cytotoxicity  Excessive Glutamate  Ogd/r  Pi3k/akt  Nrf2/ho-1  Mtor  
Exploiting new strategies in combating head and neck carcinoma: A comprehensive review on phytochemical approaches passing through PI3K/Akt/mTOR signaling pathway Journal article
Iranpanah, Amin, Majnooni, Mohammad Bagher, Biganeh, Hossein, Amirian, Roshanak, Rastegari-Pouyani, Mohsen, Filosa, Rosanna, Cheang, Wai San, Fakhri, Sajad, Khan, Haroon. Exploiting new strategies in combating head and neck carcinoma: A comprehensive review on phytochemical approaches passing through PI3K/Akt/mTOR signaling pathway[J]. Phytotherapy Research, 2024, 38(7), 3736-3762.
Authors:  Iranpanah, Amin;  Majnooni, Mohammad Bagher;  Biganeh, Hossein;  Amirian, Roshanak;  Rastegari-Pouyani, Mohsen; et al.
Favorite | TC[WOS]:0 TC[Scopus]:1  IF:6.1/7.0 | Submit date：2024/09/03
Cancer  Head And Neck  Phytochemical  Pi3k/akt/mtor Pathway  
ACE2 mediates tryptophan alleviation on diarrhea by repairing intestine barrier involved mTOR pathway Journal article
Li, Jinze, Yan, Yingli, Fu, Yang, Chen, Zhe, Yang, Yongjie, Li, Yu, Pan, Jie, Li, Feiwu, Zha, Cuifang, Miao, Kai, Ben, Lukuyu, Saleemi, Muhammad Kashif, Zhu, Yongwen, Ye, Hui, Yang, Lin, Wang, Wence. ACE2 mediates tryptophan alleviation on diarrhea by repairing intestine barrier involved mTOR pathway[J]. CELLULAR & MOLECULAR BIOLOGY LETTERS, 2024, 29(1), 90.
Authors:  Li, Jinze;  Yan, Yingli;  Fu, Yang;  Chen, Zhe;  Yang, Yongjie; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:9.2/8.1 | Submit date：2024/07/04
Ace2  Tryptophan  B0at1  Mtor  Aryl Hydrocarbon Receptor  
Tongguan capsule for treating myocardial ischemia-reperfusion injury: integrating network pharmacology and mechanism study Journal article
Liu,Jiantao, Liu,Chunping, Chen,Huiqi, Cen,Huan, Yang,Hailong, Liu,Peijian, Liu,Fang, Ma,Liuling, Chen,Quanfu, Wang,Lei. Tongguan capsule for treating myocardial ischemia-reperfusion injury: integrating network pharmacology and mechanism study[J]. PHARMACEUTICAL BIOLOGY, 2023, 61(1), 437-448.
Authors:  Liu,Jiantao;  Liu,Chunping;  Chen,Huiqi;  Cen,Huan;  Yang,Hailong; et al.
Favorite | TC[WOS]:6 TC[Scopus]:7  IF:3.9/4.0 | Submit date：2023/08/03
Hypoxia/reoxygenation  Apoptosis  Mtor Pathways  Autophagy  
Proteotoxic stress disrupts epithelial integrity by inducing MTOR sequestration and autophagy overactivation Journal article
Xiaoxiang Cheng, Pei Zhang, Hongyu Zhao, Hui Zheng, Kai Zheng, Hong Zhang, Hongjie Zhang. Proteotoxic stress disrupts epithelial integrity by inducing MTOR sequestration and autophagy overactivation[J]. Autophagy, 2023, 19(1), 241 - 255.
Authors:  Xiaoxiang Cheng;  Pei Zhang;  Hongyu Zhao;  Hui Zheng;  Kai Zheng; et al.
Favorite | TC[WOS]:3 TC[Scopus]:3  IF:14.6/16.8 | Submit date：2022/08/04
Autophagy  C. Elegans  Endosomal Degradation  Epithelial Morphogenesis  Let-363/mtor  Proteostasis  
Morusin and mulberrin extend the lifespans of yeast and C. elegans via suppressing nutrient-sensing pathways Journal article
Xu, Pingkang, Chen, Qimin, Chen, Xiaoman, Qi, Hao, Yang, Yuyan, Li, Weiqi, Yang, Xin, Gunawan, Amelia, Chen, Shuoyu, Zhang, Huimin, Shen, Han Ming, Huang, Dejian, Kennedy, Brian, Xu, Li, Wu, Ziyun. Morusin and mulberrin extend the lifespans of yeast and C. elegans via suppressing nutrient-sensing pathways[J]. GeroScience, 2022, 45(2), 949-964.
Authors:  Xu, Pingkang;  Chen, Qimin;  Chen, Xiaoman;  Qi, Hao;  Yang, Yuyan; et al.
Favorite | TC[WOS]:5 TC[Scopus]:7  IF:5.3/6.2 | Submit date：2023/01/30
Antiaging  Mtor/s6k1  Mulberry  Prenylated Flavonoids  Structure–activity Relationship  
Chelerythrine ameliorates rheumatoid arthritis by modulating the AMPK/mTOR/ULK-1 signaling pathway Journal article
Cai, Jun, Zhang, Lu Chen, Zhao, Ren Jie, Pu, Li Min, Chen, Ke Yuan, Nasim, Ali Adnan, Elaine Lai-Han Leung, Fan, Xing Xing. Chelerythrine ameliorates rheumatoid arthritis by modulating the AMPK/mTOR/ULK-1 signaling pathway[J]. Phytomedicine, 2022, 104.
Authors:  Cai, Jun;  Zhang, Lu Chen;  Zhao, Ren Jie;  Pu, Li Min;  Chen, Ke Yuan; et al.
Favorite | TC[WOS]:17 TC[Scopus]:19  IF:6.7/6.2 | Submit date：2023/01/30
Ampk/mtor/ulk-1  Apoptosis  Autophagy  Chelerythrine  Rheumatoid Arthritis  
Presenilin-1 F105C mutation leads to tau accumulation in human neurons via the Akt/mTORC1 signaling pathway Journal article
Chong, Cheong Meng, Tan, Yuan, Tong, Jiaqi, Ke, Minjing, Zhang, Ke, Yan, Lingli, Cen, Xiaotong, Lu, Jia Hong, Chen, Guobing, Su, Huanxing, Qin, Dajiang. Presenilin-1 F105C mutation leads to tau accumulation in human neurons via the Akt/mTORC1 signaling pathway[J]. Cell and Bioscience, 2022, 12(1), 131.
Authors:  Chong, Cheong Meng;  Tan, Yuan;  Tong, Jiaqi;  Ke, Minjing;  Zhang, Ke; et al.
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:6.1/7.0 | Submit date：2023/01/30
Mtor  Presenilin-1  Ipsc  Crispr/cas9  
Synthesis and anticancer evaluations of novel 1H-imidazole [4,5-f][1,10] phenanthroline derivative for the treatment of colorectal cancer Journal article
Hu, Shujian, Ma, Wantong, Wang, Junyi, Ma, Yunhao, Zhou, Zhongkun, Zhang, Rentao, Du, Kangjia, Zhang, Hao, Sun, Mengze, Jiang, Xinrong, Tu, Hongyuan, Tang, Xiaoliang, Yao, Xiaojun, Chen, Peng. Synthesis and anticancer evaluations of novel 1H-imidazole [4,5-f][1,10] phenanthroline derivative for the treatment of colorectal cancer[J]. European Journal of Pharmacology, 2022, 928.
Authors:  Hu, Shujian;  Ma, Wantong;  Wang, Junyi;  Ma, Yunhao;  Zhou, Zhongkun; et al.
Favorite | TC[WOS]:7 TC[Scopus]:9  IF:4.2/4.3 | Submit date：2023/01/30
1h-imidazole [4,5-f][1,10] Phenanthroline  Apoptosis  Cell Cycle  Colorectal Cancer  Mtor