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A NIR iridium(III) complex-based luminescence probe for imaging mitochondria pyruvate dehydrogenase kinase 1 in triple-negative breast cancer cells Journal article
Jing, Shaozhen, Song, Ying Qi, Liu, Jingqi, Zhao, Chen, Wang, Ling, Chan, Daniel Shiu Hin, Wong, Chun Yuen, Lee, Simon Ming Yuen, Wang, Jing, Leung, Chung Hang, Wang, Wanhe. A NIR iridium(III) complex-based luminescence probe for imaging mitochondria pyruvate dehydrogenase kinase 1 in triple-negative breast cancer cells[J]. Sensors and Actuators B: Chemical, 2024, 418, 136265.
Authors:  Jing, Shaozhen;  Song, Ying Qi;  Liu, Jingqi;  Zhao, Chen;  Wang, Ling; et al.
Favorite | TC[WOS]:0 TC[Scopus]:1  IF:8.0/7.0 | Submit date：2024/08/05
Breast Cancer  Dichloroacetic Acid (Dca)  Iridium(Iii) Complex  Mitochondrial Targeting  Nir Imaging  Pyruvate Dehydrogenase Kinase 1 (Pdk1)  
Combined inhibition of pyruvate dehydrogenase kinase 1 and hexokinase 2 induces apoptsis in non-small cell lung cancer cell models Journal article
Guo, Yizhen, Lu, Xianchen, Zhou, Yan, Chen, Wen Hua, Tam, Kin Yip. Combined inhibition of pyruvate dehydrogenase kinase 1 and hexokinase 2 induces apoptsis in non-small cell lung cancer cell models[J]. Experimental Cell Research, 2023, 433(2), 113830.
Authors:  Guo, Yizhen;  Lu, Xianchen;  Zhou, Yan;  Chen, Wen Hua;  Tam, Kin Yip
Favorite | TC[WOS]:0 TC[Scopus]:1  IF:3.3/3.3 | Submit date：2024/01/02
Cancer Metabolism  Combination Therapy  Hk2  Nsclc  Pdk1  
Dichloroacetophenone biphenylsulfone ethers as anticancer pyruvate dehydrogenase kinase inhibitors in non-small cell lung cancer models Journal article
Guo, Yizhen, Zhou, Yan, Wu, Puhua, Ran, Maoxin, Xu, Ngai, Shan, Wenying, Sha, Ou, Tam, Kin Yip. Dichloroacetophenone biphenylsulfone ethers as anticancer pyruvate dehydrogenase kinase inhibitors in non-small cell lung cancer models[J]. Chemico-Biological Interactions, 2023, 378, 110467.
Authors:  Guo, Yizhen;  Zhou, Yan;  Wu, Puhua;  Ran, Maoxin;  Xu, Ngai; et al.
Favorite | TC[WOS]:6 TC[Scopus]:6  IF:4.7/4.6 | Submit date：2023/07/19
Anticancer Effect  Dichloroacetophenone  Metabolic Alteration  Nsclc  Pdk  
Targeting glucose metabolism to develop anticancer treatments and therapeutic patents Review article
2022
Authors:  Zhou, Yan;  Guo, Yizhen;  Tam, Kin Yip
Favorite | TC[WOS]:23 TC[Scopus]:23  IF:5.4/6.4 | Submit date：2022/05/17
Cancer Glucose Metabolism  Cancer Treatment Patent  Glycolytic Inhibitor  Hexokinase 2 (Hk2)  Lactate Dehydrogenase a (Ldha)  Pyruvate Dehydrogenase Kinase (Pdk)  Warburg Effect  
Targeting glucose metabolism to develop anticancer treatments and therapeutic patents Journal article
Zhou Yan, Guo Yizhen, TAM KIN YIP. Targeting glucose metabolism to develop anticancer treatments and therapeutic patents[J]. EXPERT OPINION ON THERAPEUTIC PATENTS, 2022, 32(4), 441-453.
Authors:  Zhou Yan;  Guo Yizhen;  TAM KIN YIP
Adobe PDF | Favorite | TC[WOS]:23 TC[Scopus]:23  IF:5.4/6.4 | Submit date：2024/08/29
Cancer Treatment Patent  Cancer Glucose Metabolism  Warburg Effect  Hexokinase 2 (Hk2)  Pyruvate Dehydrogenase Kinase (Pdk)  Lactate Dehydrogenase a (Ldha)  Glycolytic Inhibitor  
Transforming Growth Factor b Mediates Drug Resistance by Regulating the Expression of Pyruvate Dehydrogenase Kinase 4 in Colorectal Cancer Journal article
Wang, S. M.. Transforming Growth Factor b Mediates Drug Resistance by Regulating the Expression of Pyruvate Dehydrogenase Kinase 4 in Colorectal Cancer[J]. JBC, 2016, 17405-17416.
Authors:  Wang, S. M.
Favorite | TC[WOS]:32 TC[Scopus]:32 | Submit date：2022/07/27
5-fu  Parp  Pdh  Pdk  Colon Cancer