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α-mangostin derivative 4e as a PDE4 inhibitor promote proteasomal degradation of alpha-synuclein in Parkinson's disease models through PKA activation Journal article
Chen, Jia Yue, Zhu, Qi, Cai, Cui Zan, Luo, Hai Bin, Lu, Jia Hong. α-mangostin derivative 4e as a PDE4 inhibitor promote proteasomal degradation of alpha-synuclein in Parkinson's disease models through PKA activation[J]. Phytomedicine, 2022, 101, 154125.
Authors:  Chen, Jia Yue;  Zhu, Qi;  Cai, Cui Zan;  Luo, Hai Bin;  Lu, Jia Hong
Favorite | TC[WOS]:8 TC[Scopus]:8  IF:6.7/6.2 | Submit date：2022/05/31
Alpha-synuclein (Α-syn)  Parkinson's Disease  Phosphodiesterase 4 Inhibitor  Protein Kinase a (Pka)  Ubiquitin-proteasome System (Ups)  
Natural alkaloid harmine promotes degradation of alpha-synuclein via PKA-mediated ubiquitin-proteasome system activation Journal article
Cai,Cui Zan, Zhou,He Feng, Yuan,Ning Ning, Wu,Ming Yue, Lee,Simon Ming Yuen, Ren,Jiao Yan, Su,Huan Xing, Lu,Jin Jian, Chen,Xiu Ping, Li,Min, Tan,Jie Qiong, Lu,Jia Hong. Natural alkaloid harmine promotes degradation of alpha-synuclein via PKA-mediated ubiquitin-proteasome system activation[J]. Phytomedicine, 2019, 61.
Authors:  Cai,Cui Zan;  Zhou,He Feng;  Yuan,Ning Ning;  Wu,Ming Yue;  Lee,Simon Ming Yuen; et al.
Favorite | TC[WOS]:33 TC[Scopus]:38  IF:6.7/6.2 | Submit date：2021/03/01
-synuclein  Harmine  Parkinson's Disease  Protein Kinase a  Ubiquitin-proteasome System  
GLUT12 promotes prostate cancer cell growth and is regulated by androgens and CaMKK2 signaling Journal article
White, Mark A., Tsouko, Efrosini, Lin, Chenchu, Rajapakshe, Kimal, Spencer, Jeffrey M., Wilkenfeld, Sandi R., Vakili, Sheiva S., Pulliam, Thomas L., Awad, Dominik, Nikolos, Fotis, Katreddy, Rajasekhara Reddy, Kaipparettu, Benny Abraham, Sreekumar, Arun, Zhang, Xiaoliu, Cheung, Edwin, Coarfa, Cristian, Frigo, Daniel E.. GLUT12 promotes prostate cancer cell growth and is regulated by androgens and CaMKK2 signaling[J]. ENDOCRINE-RELATED CANCER, 2018, 25(4), 453-469.
Authors:  White, Mark A.;  Tsouko, Efrosini;  Lin, Chenchu;  Rajapakshe, Kimal;  Spencer, Jeffrey M.; et al.
Favorite | TC[WOS]:46 TC[Scopus]:47  IF:4.1/4.4 | Submit date：2018/10/30
Glut12  Slc2a12  Glucose Metabolism  Androgen Receptor (Ar)  Calcium/calmodulin-dependent Protein Kinase Kinase 2 (Camkk2)  5 '-amp-activated Protein Kinase (Ampk)  Prostate Cancer  
PKCδ-dependent deubiquitination and stabilization of Gadd45 in A431 cells overexposed to EGF Journal article
Leung C.-H., Lam W., Zhuang W.-J., Wang N.-S., Fong W.F.. PKCδ-dependent deubiquitination and stabilization of Gadd45 in A431 cells overexposed to EGF[J]. Biochemical and Biophysical Research Communications, 2001, 285(2), 283-288.
Authors:  Leung C.-H.;  Lam W.;  Zhuang W.-J.;  Wang N.-S.;  Fong W.F.
Favorite | TC[WOS]:16 TC[Scopus]:15 | Submit date：2018/11/06
A431 Cell  Epidermal Growth Factor  Gadd45  Protein Kinase c  Ubiquitination