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Combined inhibition of pyruvate dehydrogenase kinase 1 and lactate dehydrogenase a induces metabolic and signaling reprogramming and enhances lung adenocarcinoma cell killing Journal article
Zhou, Yan, Guo, Yizhen, Ran, Maoxin, Shan, Wenying, Granchi, Carlotta, Giovannetti, Elisa, Minutolo, Filippo, Peters, Godefridus J., Tam, Kin Yip. Combined inhibition of pyruvate dehydrogenase kinase 1 and lactate dehydrogenase a induces metabolic and signaling reprogramming and enhances lung adenocarcinoma cell killing[J]. Cancer Letters, 2023, 577, 216425.
Authors:  Zhou, Yan;  Guo, Yizhen;  Ran, Maoxin;  Shan, Wenying;  Granchi, Carlotta; et al.
Favorite | TC[WOS]:9 TC[Scopus]:7  IF:9.1/8.3 | Submit date：2023/12/04
Anticancer  Combination Treatment  Non-small Cell Lung Cancer  Warburg Effect  
Targeting lactate-related cell cycle activities for cancer therapy Journal article
Lin, Jia, Liu, Geng, Chen, Lidian, Kwok, Hang Fai, Lin, Yao. Targeting lactate-related cell cycle activities for cancer therapy[J]. Seminars in Cancer Biology, 2022, 86, 1231-1243.
Authors:  Lin, Jia;  Liu, Geng;  Chen, Lidian;  Kwok, Hang Fai;  Lin, Yao
Favorite | TC[WOS]:26 TC[Scopus]:25  IF:12.1/13.2 | Submit date：2022/12/01
Cancer  Cell Cycle  Lactate  Lactylation  Warburg Effect  
Targeting glucose metabolism to develop anticancer treatments and therapeutic patents Review article
2022
Authors:  Zhou, Yan;  Guo, Yizhen;  Tam, Kin Yip
Favorite | TC[WOS]:22 TC[Scopus]:21  IF:5.4/6.4 | Submit date：2022/05/17
Cancer Glucose Metabolism  Cancer Treatment Patent  Glycolytic Inhibitor  Hexokinase 2 (Hk2)  Lactate Dehydrogenase a (Ldha)  Pyruvate Dehydrogenase Kinase (Pdk)  Warburg Effect  
Targeting glucose metabolism to develop anticancer treatments and therapeutic patents Journal article
Zhou Yan, Guo Yizhen, TAM KIN YIP. Targeting glucose metabolism to develop anticancer treatments and therapeutic patents[J]. EXPERT OPINION ON THERAPEUTIC PATENTS, 2022, 32(4), 441-453.
Authors:  Zhou Yan;  Guo Yizhen;  TAM KIN YIP
Adobe PDF | Favorite | TC[WOS]:22 TC[Scopus]:21  IF:5.4/6.4 | Submit date：2024/08/29
Cancer Treatment Patent  Cancer Glucose Metabolism  Warburg Effect  Hexokinase 2 (Hk2)  Pyruvate Dehydrogenase Kinase (Pdk)  Lactate Dehydrogenase a (Ldha)  Glycolytic Inhibitor  
Function of DHX33 in promoting Warburg effect via regulation of glycolytic genes Journal article
Peng,Cheng, Hou,Sheng Tao, Deng,Chu Xia, Zhang,Yandong. Function of DHX33 in promoting Warburg effect via regulation of glycolytic genes[J]. JOURNAL OF CELLULAR PHYSIOLOGY, 2021, 236(2), 981-996.
Authors:  Peng,Cheng;  Hou,Sheng Tao;  Deng,Chu Xia;  Zhang,Yandong
Favorite | TC[WOS]:11 TC[Scopus]:9  IF:4.5/5.3 | Submit date：2021/03/02
Demethylation  Dhx33  Gadd45a  Glycolysis  Rna Helicase  Warburg Effect  
Lysyl oxidase promotes liver metastasis of gastric cancer via facilitating the reciprocal interactions between tumor cells and cancer associated fibroblasts Journal article
Li, Q, Zhu, CC, Ni, B, Zhang, ZZ, Jiang, SH, Hu, LP, Wang, X, Zhang,XX, Huang, PQ, Yang, Q, Li, J, Gu, JR, Xu, J, Luo, KQ, Zhao, G, Zhang, ZG. Lysyl oxidase promotes liver metastasis of gastric cancer via facilitating the reciprocal interactions between tumor cells and cancer associated fibroblasts[J]. EBioMedicine, 2019, 49, 157-171.
Authors:  Li, Q;  Zhu, CC;  Ni, B;  Zhang, ZZ;  Jiang, SH; et al.
Favorite | TC[WOS]:65 TC[Scopus]:65  IF:9.7/9.2 | Submit date：2022/08/26
Gastric Cancer  Liver Metastasis  Lox  Cafs  Warburg Effect  
Lysyl oxidase promotes liver metastasis of gastric cancer via facilitating the reciprocal interactions between tumor cells and cancer associated fibroblasts Journal article
Li, Qing, Zhu, Chun Chao, Ni, Bo, Zhang, Zi Zhen, Jiang, Shu Heng, Hu, Li Peng, Wang, Xu, Zhang, Xiao Xin, Huang, Pei Qi, Yang, Qin, Li, Jun, Gu, Jian Ren, Xu, Jia, Luo, Kathy Qian, Zhao, Gang, Zhang, Zhi Gang. Lysyl oxidase promotes liver metastasis of gastric cancer via facilitating the reciprocal interactions between tumor cells and cancer associated fibroblasts[J]. EBioMedicine, 2019, 49, 157-171.
Authors:  Li, Qing;  Zhu, Chun Chao;  Ni, Bo;  Zhang, Zi Zhen;  Jiang, Shu Heng; et al.
Favorite | TC[WOS]:65 TC[Scopus]:65  IF:9.7/9.2 | Submit date：2021/03/02
Cafs  Gastric Cancer  Liver Metastasis  Lox  Warburg Effect  
Warburg Effects in Cancer and Normal Proliferating Cells: Two Tales of the Same Name Journal article
Sun, Huiyan, Chen, Liang, Cao, Sha, Liang, Yanchun, Xu, Ying. Warburg Effects in Cancer and Normal Proliferating Cells: Two Tales of the Same Name[J]. Genomics, Proteomics and Bioinformatics, 2019, 17(3), 273-286.
Authors:  Sun, Huiyan;  Chen, Liang;  Cao, Sha;  Liang, Yanchun;  Xu, Ying
Favorite | TC[WOS]:36 TC[Scopus]:41  IF:11.5/10.3 | Submit date：2022/05/17
Cancer  Cell Proliferation  Fenton Reaction  Ph Homeostasis  Warburg Effect  
OTUB2 stabilizes U2AF2 to promote the Warburg effect and tumorigenesis via the AKT/mTOR signaling pathway in non-small cell lung cancer Journal article
Jing Li, Dongdong Cheng, Miaoxin Zhu, Huajian Yu, Zhen Pan, Lei Liu, Qin Geng, Hongyu Pan, Mingxia Yan, Ming Yao. OTUB2 stabilizes U2AF2 to promote the Warburg effect and tumorigenesis via the AKT/mTOR signaling pathway in non-small cell lung cancer[J]. Theranostics, 2019, 9(1), 179-195.
Authors:  Jing Li;  Dongdong Cheng;  Miaoxin Zhu;  Huajian Yu;  Zhen Pan; et al.
Favorite | TC[WOS]:104 TC[Scopus]:100  IF:12.4/12.0 | Submit date：2020/03/11
Deubiquitinating Enzyme  Otub2  Nsclc  Warburg Effect  U2af2  
Identification of Novel Pyruvate Dehydrogenase Kinase 1 (PDK1) Inhibitors by Kinase Activity-Based High-Throughput Screening for Anticancer Therapeutics Journal article
Zhang W., Hu X., Chakravarty H., Yang Z., Tam K.Y.. Identification of Novel Pyruvate Dehydrogenase Kinase 1 (PDK1) Inhibitors by Kinase Activity-Based High-Throughput Screening for Anticancer Therapeutics[J]. ACS Combinatorial Science, 2018, 20(11), 660-671.
Authors:  Zhang W.;  Hu X.;  Chakravarty H.;  Yang Z.;  Tam K.Y.
Favorite | TC[WOS]:12 TC[Scopus]:12 | Submit date：2018/12/18
Cancer  High-throughput Screening  Pyruvate Dehydrogenase Kinase 1  Small Molecule Inhibitors  Warburg Effect