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Anti-diabetic potential of apigenin, luteolin, and baicalein via partially activating PI3K/Akt/Glut-4 signaling pathways in insulin-resistant HepG2 cells Journal article
Miao, Lingchao, Zhang, Haolin, Cheong, Meng Sam, Zhong Ruting, Garcia-Oliveira, Paula, Prieto, Miguel A, Cheng, Ka-Wing, Wang, Mingfu, Cao, Hui, Nie, Shaoping, Simal-Gandara, Jesus, Cheang, Wai San, Xiao, Jianbo. Anti-diabetic potential of apigenin, luteolin, and baicalein via partially activating PI3K/Akt/Glut-4 signaling pathways in insulin-resistant HepG2 cells[J]. Food Science and Human Wellness, 2023, 12(6), 1991-2000.
Authors:  Miao, Lingchao;  Zhang, Haolin;  Cheong, Meng Sam;  Zhong Ruting;  Garcia-Oliveira, Paula; et al.
Favorite | TC[WOS]:23 TC[Scopus]:21  IF:5.6/6.8 | Submit date：2022/08/11
Apigenin  Luteolin  Baicalein  Insulin-resistant Hepg2 Cells  Signaling Pathway  Reactive Oxygen Species (Ros)  Advanced Glycation End-products (Ages)  Glycogen Synthase Kinase (Gsk-3β)  Glucose Transporter Protein 4 (Glut4)  
Mitochondrial toxicity evaluation of traditional Chinese medicine injections with a dual in vitro approach Journal article
Shen, Yunfu, Guo, Kaiqiang, Ma, Aijun, Huang, Zhe, Du, Jingjing, Chen, Junhe, Lin, Qianyu, Wei, Chengming, Wang, Zi, Zhang, Fuming, Zhang, Juan, Lin, Wanjun, Feng, Na, Ma, Wenzhe. Mitochondrial toxicity evaluation of traditional Chinese medicine injections with a dual in vitro approach[J]. Frontiers in Pharmacology, 2022, 13.
Authors:  Shen, Yunfu;  Guo, Kaiqiang;  Ma, Aijun;  Huang, Zhe;  Du, Jingjing; et al.
Favorite | TC[WOS]:1 TC[Scopus]:3  IF:4.4/5.0 | Submit date：2023/01/31
Adverse Drug Reactions  Glucose/galactose Assay  Hepg2 Cells  Mitochondrial Toxicity  Tcm Injections  
3,3′,4,5′-Tetramethoxy-trans-stilbene Improves Insulin Resistance by Activating the IRS/PI3K/Akt Pathway and Inhibiting Oxidative Stress Journal article
Tan, Yi, Miao, Lingchao, Xiao, Jianbo, Cheang, Wai San. 3,3′,4,5′-Tetramethoxy-trans-stilbene Improves Insulin Resistance by Activating the IRS/PI3K/Akt Pathway and Inhibiting Oxidative Stress[J]. Current Issues in Molecular Biology, 2022, 44(5), 2175-2185.
Authors:  Tan, Yi;  Miao, Lingchao;  Xiao, Jianbo;  Cheang, Wai San
Favorite | TC[WOS]:12 TC[Scopus]:13  IF:2.8/2.9 | Submit date：2022/05/31
3,3′,4,5′-tetramethoxy-trans-stilbene  Glucose Consumption  Glycogen Synthesis  Hepg2 Cells  Insulin Resistance  Oxidative Stress  
Sodium Butyrate Modulated Mitochondria Function in High-Insulin induced HepG2 Cells Dysfunction. Journal article
Zhao, T, Gu, J, Zhang, H, Wang, Z, Zhang, W, Zhao, Y., Zheng, Y, Zhang, W, Zhou, H, Zhang, G, Sun, Q, Zhou, E, Liu, Z, Xu, Y. Sodium Butyrate Modulated Mitochondria Function in High-Insulin induced HepG2 Cells Dysfunction.[J]. Oxidative Medicine and Cellular Longevity, 2020, 2020, 1904609.
Authors:  Zhao, T;  Gu, J;  Zhang, H;  Wang, Z;  Zhang, W; et al.
Adobe PDF | Favorite | TC[WOS]:26 TC[Scopus]:28  IF:7.310/8.427 | Submit date：2022/07/27
Sodium Butyrate  Mitochondrial Function  High-insulin Induced Hepg2 Cell  
Agrimonolide and Desmethylagrimonolide Induced HO-1 Expression in HepG2 Cells through Nrf2-Transduction and p38 Inactivation Journal article
Chen, Lei, Teng, Hui, Zhang, Kalin Yanbo, Skalicka-Wozniak, Krystyna, Georgiev, Milen I., Xiao, Jianbo. Agrimonolide and Desmethylagrimonolide Induced HO-1 Expression in HepG2 Cells through Nrf2-Transduction and p38 Inactivation[J]. FRONTIERS IN PHARMACOLOGY, 2017, 7.
Authors:  Chen, Lei;  Teng, Hui;  Zhang, Kalin Yanbo;  Skalicka-Wozniak, Krystyna;  Georgiev, Milen I.; et al.
Favorite | TC[WOS]:25 TC[Scopus]:32  IF:4.4/5.0 | Submit date：2018/10/30
Agrimonolide  Desmethylagrimonolide  Hepg2 Cells  Nrf2  Heme Oxygenase-1  P38 Mapk Signaling Pathway  
Agrimonolide and desmethylagrimonolide induced HO-1 expression in HepG2 cells through Nrf2-transduction and p38 inactivation Journal article
Chen L., Teng H., Zhang K.Y., Skalicka-Wozniak K., Georgiev M.I., Xiao J.. Agrimonolide and desmethylagrimonolide induced HO-1 expression in HepG2 cells through Nrf2-transduction and p38 inactivation[J]. Frontiers in Pharmacology, 2017, 7(JAN).
Authors:  Chen L.;  Teng H.;  Zhang K.Y.;  Skalicka-Wozniak K.;  Georgiev M.I.; et al.
Favorite | TC[WOS]:25 TC[Scopus]:32 | Submit date：2019/01/15
Agrimonolide  Desmethylagrimonolide  Heme Oxygenase-1  Hepg2 Cells  Nrf2  P38 Mapk Signaling Pathway  
Polyphyllin VII induces apoptosis in HepG2 cells through ROS-mediated mitochondrial dysfunction and MAPK pathways Journal article
Zhang C., Jia X., Bao J., Chen S., Wang K., Zhang Y., Li P., Wan J.-B., Su H., Wang Y., Mei Z., He C.. Polyphyllin VII induces apoptosis in HepG2 cells through ROS-mediated mitochondrial dysfunction and MAPK pathways[J]. BMC complementary and alternative medicine, 2016, 16, 58.
Authors:  Zhang C.;  Jia X.;  Bao J.;  Chen S.;  Wang K.; et al.
Favorite | TC[WOS]:74 TC[Scopus]:85  IF:4.782/4.479 | Submit date：2018/10/31
Polyphyllin Vii  Apoptosis  Mapk Pathways  Anticancer  Hepg2 Cells  
Proteomic Analysis of HepG2 Hepatocellular Carcinoma cells Treated with Platycodin D Journal article
Lu, J., Lu, DZ, Chen, YF, Dong, YT, Zhang, JR, Li, T, Tang, ZH, Yang, Z. Proteomic Analysis of HepG2 Hepatocellular Carcinoma cells Treated with Platycodin D[J]. Chinese Journal of Natural Medicines, 2015, 673-679.
Authors:  Lu, J.;  Lu, DZ;  Chen, YF;  Dong, YT;  Zhang, JR; et al.
Favorite |   IF:4.0/3.7 | Submit date：2022/03/31
Platycodin d  Hepg2  Proteome  2-d Dige  
Proteomic analysis of hepatocellular carcinoma HepG2 cells treated with platycodin D Journal article
Jin-Jian LU, De-Zhao LU, Yu-Fei CHEN, Ya-Ting DONG, Jun-Ren ZHANG, Ting LI, Zheng-Hai TANG, Zhen YANG. Proteomic analysis of hepatocellular carcinoma HepG2 cells treated with platycodin D[J]. Chinese Journal of Natural Medicines, 2015, 13(9), 673-679.
Authors:  Jin-Jian LU;  De-Zhao LU;  Yu-Fei CHEN;  Ya-Ting DONG;  Jun-Ren ZHANG; et al.
Favorite | TC[Scopus]:23 | Submit date：2018/12/28
2-d Dige  Hepg2  Platycodin d  Proteome  
Platycodin D triggers autophagy through activation of extracellular signal-regulated kinase in hepatocellular carcinoma HepG2 cells Journal article
Ting Li, Zheng-Hai Tang, Wen-Shan Xu, Guo-Sheng Wu, Ya-Fang Wang, Lin-Lin Chang, Hong Zhu, Xiu-Ping Chen, Yi-Tao Wang, Yi Chen, Jin-Jian Lu. Platycodin D triggers autophagy through activation of extracellular signal-regulated kinase in hepatocellular carcinoma HepG2 cells[J]. European Journal of Pharmacology, 2015, 749, 81.
Authors:  Ting Li;  Zheng-Hai Tang;  Wen-Shan Xu;  Guo-Sheng Wu;  Ya-Fang Wang; et al.
Favorite | TC[WOS]:48 TC[Scopus]:48  IF:4.2/4.3 | Submit date：2018/10/31
Autophagy  Chloroquine  Erk  Hepg2  Platycodin d  Protective