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Shear Stress Drives the Cleavage Activation of Protease-Activated Receptor 2 by PRSS3/Mesotrypsin to Promote Invasion and Metastasis of Circulating Lung Cancer Cells Journal article
Zhou, Muya, Li, Koukou, Luo, Kathy Qian. Shear Stress Drives the Cleavage Activation of Protease-Activated Receptor 2 by PRSS3/Mesotrypsin to Promote Invasion and Metastasis of Circulating Lung Cancer Cells[J]. Advanced Science, 2023, 10(25), 2301059 (1-21).
Authors:  Zhou, Muya;  Li, Koukou;  Luo, Kathy Qian
Favorite | TC[WOS]:1 TC[Scopus]:2  IF:14.3/16.3 | Submit date：2023/08/03
Cancer Metastasis  Circulating Tumor Cells  Protease-activated Receptor 2  Prss3/mesotrypsin  Shear Stress  
Combining computational and experimental evidence on the activity of antimalarial drugs on papain-like protease of SARS-CoV-2: A repurposing study Journal article
Ribaudo, Giovanni, Yun, Xiaoyun, Ongaro, Alberto, Oselladore, Erika, Ng, Jerome P L., Haynes, Richard K., Law, Betty Yuen Kwan, Memo, Maurizio, Wong, Vincent Kam Wai, Coghi, Paolo, Gianoncelli, Alessandra. Combining computational and experimental evidence on the activity of antimalarial drugs on papain-like protease of SARS-CoV-2: A repurposing study[J]. Chemical Biology and Drug Design, 2022.
Authors:  Ribaudo, Giovanni;  Yun, Xiaoyun;  Ongaro, Alberto;  Oselladore, Erika;  Ng, Jerome P L.; et al.
Favorite | TC[WOS]:3 TC[Scopus]:3  IF:3.2/2.9 | Submit date：2023/01/30
Antimalarial Drugs  Drug Repurposing  Papain-like Protease  Pl-pro  Sars-cov-2  
USP13: Multiple functions and target Inhibition Journal article
Xiaolong Li, Ge Yang, Wenyao Zhang, Biying Qin, Zifan Ye, Huijing Shi, Xinmeng Zhao, Yihang Chen, Bowei Song, Ziqing Mei. USP13: Multiple functions and target Inhibition[J]. Frontiers in cell and developmental biology, 2022, 10, 875124.
Authors:  Xiaolong Li;  Ge Yang;  Wenyao Zhang;  Biying Qin;  Zifan Ye; et al.
Favorite | TC[WOS]:14 TC[Scopus]:13  IF:4.6/5.2 | Submit date：2023/08/28
Deubiquitination  Disease  Inhibitor  Structure  Ubiquitin-specific Protease 13  
USP13: Multiple Functions and Target Inhibition Journal article
Li, Xiaolong, Yang, Ge, Zhang, Wenyao, Qin, Biying, Ye, Zifan, Shi, Huijing, Zhao, Xinmeng, Chen, Yihang, Song, Bowei, Mei, Ziqing, Zhao, Qi, Wang, Feng. USP13: Multiple Functions and Target Inhibition[J]. Frontiers in Cell and Developmental Biology, 2022, 10, 875124.
Authors:  Li, Xiaolong;  Yang, Ge;  Zhang, Wenyao;  Qin, Biying;  Ye, Zifan; et al.
Favorite | TC[WOS]:14 TC[Scopus]:13  IF:4.6/5.2 | Submit date：2022/05/04
Deubiquitination  Disease  Inhibitor  Structure  Ubiquitin-specific Protease 13  
Proteases -- From Basic Structure to Function to Drug Design as Targeted Therapy Book
Kwok, H. F., Shaw, C., Walker, B.. Proteases -- From Basic Structure to Function to Drug Design as Targeted Therapy[M]. Switzerland:MDPI, 2021.
Authors:  Kwok, H. F.;  Shaw, C.;  Walker, B.
Favorite |  | Submit date：2022/06/14
Protease inhibitor  Drug discovery  Mode of actions  
Proteases—From Basic Structure to Function to Drug Design as Targeted Therapy Book
Kwok, Hang Fai, Shaw, Chris, Walker, Brian. Proteases—From Basic Structure to Function to Drug Design as Targeted Therapy[M]. Switzerland:MDPI, 2021.
Authors:  Kwok, Hang Fai;  Shaw, Chris;  Walker, Brian
Favorite | TC[WOS]:1 TC[Scopus]:1 | Submit date：2022/06/02
Protease Inhibitor  Targeted Therapy  Drug Design And Development  Oncology  Precision Medicine  
Fungi co-option of an insect protease gene for extracellular nutrient degradation and transcriptional control Conference paper
Li, A., Wong, K. H.. Fungi co-option of an insect protease gene for extracellular nutrient degradation and transcriptional control[C], 2019.
Authors:  Li, A.;  Wong, K. H.
Favorite |  | Submit date：2022/07/27
Fungi  insect protease  extracellular nutrient degradation  transcriptional control  
A protease gain from insect via Horizontal Gene Transfer plays regulatory roles in Aspergillus nidulans nitrogen metabolism. Conference paper
Li, A., Wong, K. H.. A protease gain from insect via Horizontal Gene Transfer plays regulatory roles in Aspergillus nidulans nitrogen metabolism.[C], 2017.
Authors:  Li, A.;  Wong, K. H.
Favorite |  | Submit date：2022/07/27
Nitrogen  protease  
The natural product cyclomarin kills mycobacterium tuberculosis by targeting the ClpC1 subunit of the caseinolytic protease Journal article
Schmitt E.K., Riwanto M., Sambandamurthy V., Roggo S., Miault C., Zwingelstein C., Krastel P., Noble C., Beer D., Rao S.P.S., Au M., Niyomrattanakit P., Lim V., Zheng J., Jeffery D., Pethe K., Camacho L.R.. The natural product cyclomarin kills mycobacterium tuberculosis by targeting the ClpC1 subunit of the caseinolytic protease[J]. Angewandte Chemie - International Edition, 2011, 50(26), 5889-5891.
Authors:  Schmitt E.K.;  Riwanto M.;  Sambandamurthy V.;  Roggo S.;  Miault C.; et al.
Favorite | TC[WOS]:142 TC[Scopus]:156 | Submit date：2019/01/16
Antibiotics  Chemical Proteomics  Clp Protease Complex  Cyclic Peptides  Natural Products  
NtCP56, a new cysteine protease in Nicotiana tabacum L., involved in pollen grain development Journal article
Zhang X.-M., Wang Y., Lv X.-M., Li H., Sun P., Lu H., Li F.-L.. NtCP56, a new cysteine protease in Nicotiana tabacum L., involved in pollen grain development[J]. Journal of Experimental Botany, 2009, 60(6), 1569-1577.
Authors:  Zhang X.-M.;  Wang Y.;  Lv X.-M.;  Li H.;  Sun P.; et al.
Favorite | TC[WOS]:32 TC[Scopus]:33 | Submit date：2019/01/16
Cysteine Protease  Ntcp56  Pollen  Tobacco