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Inhibition of USP7 upregulates USP22 and activates its downstream cancer-related signaling pathways in human cancer cells Journal article
Zhang, Keqiang, Sun, Ting, Li, Wendong, Guo, Yuming, Li, Aimin, Hsieh, Marcus, Wang, Jinghan, Wu, Jun, Arvanitis, Leonidas, Raz, Dan J.. Inhibition of USP7 upregulates USP22 and activates its downstream cancer-related signaling pathways in human cancer cells[J]. Cell Communication and Signaling, 2023, 21, 319.
Authors:  Zhang, Keqiang;  Sun, Ting;  Li, Wendong;  Guo, Yuming;  Li, Aimin; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:8.2/8.0 | Submit date：2024/01/02
C-myc  Deubiquitinase  P53  Sp1  Targeted Anticancer Therapy  Usp22  Usp7  
Identification of a novel therapeutic target for lung cancer: Mitochondrial ribosome protein L9 Journal article
Li,Xin Yuan, He,Xin Yu, Zhao,Hong, Qi,Lu, Lu,Jin Jian. Identification of a novel therapeutic target for lung cancer: Mitochondrial ribosome protein L9[J]. Pathology Research and Practice, 2023, 248, 154625.
Authors:  Li,Xin Yuan;  He,Xin Yu;  Zhao,Hong;  Qi,Lu;  Lu,Jin Jian
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:2.9/2.6 | Submit date：2023/08/03
Bioinformatics  C-myc  Lung Cancer  Mrpl9  Zeb1  
c-Myc-PD-L1 Axis Sustained Gemcitabine-Resistance in Pancreatic Cancer Journal article
Yao, Jingjing, Huang, Min, Shen, Qinghong, Ding, Ming, Yu, Shaofang, Guo, Yajuan, Lin, Yuefang, Zheng, Yaqiu, Chen, Wenbo, Yan, Wenxin, Liu, Zhongqiu, Wang, Dawei, Hu, Ming, Lu, Linlin. c-Myc-PD-L1 Axis Sustained Gemcitabine-Resistance in Pancreatic Cancer[J]. Frontiers in Pharmacology, 2022, 13.
Authors:  Yao, Jingjing;  Huang, Min;  Shen, Qinghong;  Ding, Ming;  Yu, Shaofang; et al.
Favorite | TC[WOS]:6 TC[Scopus]:6  IF:4.4/5.0 | Submit date：2023/01/30
Artesunate  C-myc  Gemcitabine Resistance  Pancreatic Cancer  Pd-l1  
c-MYC-mediated TRIB3/P62+ aggresomes accumulation triggers paraptosis upon the combination of everolimus and ginsenoside Rh2 Journal article
Su, Min Xia, Xu, Yu Lian, Jiang, Xiao Ming, Huang, Mu Yang, Zhang, Le Le, Yuan, Luo Wei, Xu, Xiao Huang, Zhu, Qi, Gao, Jian Li, Lu, Jia Hong, Chen, Xiuping, Huang, Ming Qing, Wang, Yitao, Lu, Jin Jian. c-MYC-mediated TRIB3/P62+ aggresomes accumulation triggers paraptosis upon the combination of everolimus and ginsenoside Rh2[J]. Acta Pharmaceutica Sinica B, 2022, 12(3), 1240-1253.
Authors:  Su, Min Xia;  Xu, Yu Lian;  Jiang, Xiao Ming;  Huang, Mu Yang;  Zhang, Le Le; et al.
Favorite | TC[WOS]:10 TC[Scopus]:11  IF:14.7/14.1 | Submit date：2022/04/06
Aggresomes  C-myc  Everolimus  Ginsenoside Rh2  Lung Cancer  P62  Paraptosis  Trib3  
Activation of notch 3/c-MYC/CHOP axis regulates apoptosis and promotes sensitivity of lung cancer cells to mTOR inhibitor everolimus Journal article
Li,Ting, Xu,Xiao Huang, Guo,Xia, Yuan,Tao, Tang,Zheng Hai, Jiang,Xiao Ming, Xu,Yu Lian, Zhang,Le Le, Chen,Xiuping, Zhu,Hong, Shi,Jia Jie, Lu,Jin Jian. Activation of notch 3/c-MYC/CHOP axis regulates apoptosis and promotes sensitivity of lung cancer cells to mTOR inhibitor everolimus[J]. Biochemical Pharmacology, 2020, 175.
Authors:  Li,Ting;  Xu,Xiao Huang;  Guo,Xia;  Yuan,Tao;  Tang,Zheng Hai; et al.
Favorite | TC[WOS]:17 TC[Scopus]:19  IF:5.3/5.2 | Submit date：2021/03/01
Lung Cancer  Notch 3  C-myc  Chop  Apoptosis  
Structure-based design of flavone derivatives as c-myc oncogene down-regulators Journal article
Yang H., Zhong H.-J., Leung K.-H., Chan D.S.-H., Ma V.P.-Y., Fu W.-C., Nanjunda R., Wilson W.D., Ma D.-L., Leung C.-H.. Structure-based design of flavone derivatives as c-myc oncogene down-regulators[J]. European Journal of Pharmaceutical Sciences, 2013, 48(1-2), 130-141.
Authors:  Yang H.;  Zhong H.-J.;  Leung K.-H.;  Chan D.S.-H.;  Ma V.P.-Y.; et al.
Favorite | TC[WOS]:19 TC[Scopus]:22  IF:4.3/4.2 | Submit date：2018/11/06
C-myc  Flavone Derivatives  G-quadruplex Dna  Structure-based Design  
A cyclometallated iridium(III) complex as a c-myc G-Quadruplex stabilizer and down-regulator of c-myc oncogene expression Journal article
Yang H., Ma V.P.-Y., Chan D.S.-H., He H.-Z., Leung C.-H., Ma D.-L.. A cyclometallated iridium(III) complex as a c-myc G-Quadruplex stabilizer and down-regulator of c-myc oncogene expression[J]. Current Medicinal Chemistry, 2013, 20(4), 576-582.
Authors:  ; et al.
Favorite | TC[WOS]:17 TC[Scopus]:0  IF:3.5/4.0 | Submit date：2018/10/30
C-myc  Dna  G-quadruplex  Iridium(Iii)  Metal Complex  Oncogene  Promoter  Cyclometallated Iridium(Iii) Complex  2  2'-biquinoline N-donor  
Structure-based optimization of FDA-approved drug methylene blue as a c-myc G-quadruplex DNA stabilizer Journal article
Chan D.S.-H., Yang H., Kwan M.H.-T., Cheng Z., Lee P., Bai L.-P., Jiang Z.-H., Wong C.-Y., Fong W.-F., Leung C.-H., Ma D.-L.. Structure-based optimization of FDA-approved drug methylene blue as a c-myc G-quadruplex DNA stabilizer[J]. Biochimie, 2011, 93(6), 1055-1064.
Authors:  Chan D.S.-H.;  Yang H.;  Kwan M.H.-T.;  Cheng Z.;  Lee P.; et al.
Favorite | TC[WOS]:84 TC[Scopus]:91 | Submit date：2018/11/06
C-myc G-quadruplex  Fda-approved Drug  Methylene Blue  Repurposing  Structure-based Optimization  
Effect of active compounds isolated from Pteris semipinnata L on DNA topoisomerases and tyrosine protein kinase and expression of c-myc in lung adenocarcinoma cells Journal article
Li J.-H., Liang N.-C., Mo L.-E., Zhang X., He C.-W.. Effect of active compounds isolated from Pteris semipinnata L on DNA topoisomerases and tyrosine protein kinase and expression of c-myc in lung adenocarcinoma cells[J]. Chinese Journal of Cancer Research, 2001, 13(2), 105-109.
Authors:  Li J.-H.;  Liang N.-C.;  Mo L.-E.;  Zhang X.;  He C.-W.
Favorite | TC[Scopus]:4 | Submit date：2018/12/28
C-myc  Dna Topoisomerase  Pteris Semipinnata L.  Tyrosine Protein Kinase